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Myocarditis treatment tablet and preparation method

A myocarditis and tablet technology, applied in the field of medicine, can solve problems such as harming the health of patients, and achieve the effects of good therapeutic effect, broad market prospect and reasonable composition ratio.

Inactive Publication Date: 2018-12-25
何凤姣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is no targeted drug to treat myocarditis. Usually, a combination of drugs is used, which inevitably produces unpredictable side effects and endangers the health of patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A tablet for treating myocarditis, comprising the following raw materials in parts by weight: 14 parts of otilonium bromide, 1.5 parts of perindopril, 3 parts of angelica, 2.4 parts of Radix Ophiopogon japonicus, 4 parts of polygala, 2.4 parts of licorice, 16 parts of hemp fresh leaves.

[0025] The preparation method of the tablet that is used for the treatment of myocarditis described in the present embodiment, comprises the following steps:

[0026] 1) Mince the fresh sisal leaves, drain the residue to obtain the sisal slurry, add 3 times the mass of dehydrated ethanol to the sisal slurry to obtain the extract, then concentrate the extract to the original half of the volume to obtain sisal concentrate;

[0027] 2) melt otilonium bromide for subsequent use;

[0028] 3) Dried Angelica, Ophiopogon japonicus, Polygala and Glycyrrhizae, crushed, passed through a 100-mesh sieve, mixed evenly, and fried at 103°C for 5 minutes to obtain a mixed powder;

[0029] 4) Add the...

Embodiment 2

[0034] A tablet for treating myocarditis, comprising the following raw materials in parts by weight: 16 parts of otilonium bromide, 1.9 parts of perindopril, 4 parts of angelica, 3.6 parts of Radix Ophiopogon japonicus, 5 parts of polygala, 2.8 parts of licorice, 18 parts of hemp fresh leaves.

[0035] The preparation method of the tablet that is used for the treatment of myocarditis described in the present embodiment, comprises the following steps:

[0036] 1) Mince the fresh sisal leaves, drain the residue to obtain the sisal slurry, add 5 times the mass of dehydrated ethanol to the sisal slurry to obtain the extract, then concentrate the extract to the original half of the volume to obtain sisal concentrate;

[0037] 2) melt otilonium bromide for subsequent use;

[0038] 3) Dried Angelica, Ophiopogon japonicus, Polygala and licorice, crushed, passed through a 100-mesh sieve, mixed evenly, and fried at 110°C for 7 minutes to obtain a mixed powder;

[0039] 4) Add the mix...

Embodiment 3

[0044] A tablet for treating myocarditis, comprising the following raw materials in parts by weight: 18 parts of otilonium bromide, 2.1 parts of perindopril, 6 parts of angelica, 3.9 parts of Radix Ophiopogon japonicus, 5.5 parts of polygala, 3.1 parts of licorice, sword 20 parts of hemp fresh leaves.

[0045] The preparation method of the tablet that is used for the treatment of myocarditis described in the present embodiment, comprises the following steps:

[0046] 1) Mince the fresh sisal leaves, drain the residue to obtain the sisal slurry, add 5 times the mass of dehydrated ethanol to the sisal slurry to obtain the extract, then concentrate the extract to the original half of the volume to obtain sisal concentrate;

[0047] 2) melt otilonium bromide for subsequent use;

[0048] 3) Dried Angelica, Ophiopogon japonicus, Polygala and Glycyrrhizae, crushed, passed through a 100-mesh sieve, mixed evenly, and fried at a temperature of 115°C for 7 minutes to obtain a mixed pow...

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Abstract

The invention discloses a myocarditis treatment tablet and relates to the field of medicine science, for patients with myocarditis. The tablet is prepared from, by weight, 14-21 parts of otilonium bromide, 1.5-2.7 parts of perindopril, 3-8 parts of radix angelicae sinensis, 2.4-5.3 parts of radix ophiopogonis, 4-7 parts of radix polygalae, 2.4-3.7 parts of radix glycyrrhizae, and 16-23 parts of fresh folium agaves sisalanae. The tablet is prepared from components in reasonable proportion, has good treatment effect on heart diseases such as viral myocarditis under the synergistic effect of synergistic components, namely Otilonium Bromide and Perindopril, can effectively relieve symptoms and fill the gap of the like medicines, and has wide marketing prospect.

Description

technical field [0001] The invention relates to the field of medical science and technology, in particular to a tablet for treating myocarditis and a preparation method thereof. Background technique [0002] Myocarditis refers to a disease characterized by localized or diffuse inflammatory lesions of the myocardium. According to the established Dallas criteria, the histological evidence of intramyocardial infiltration is the infiltration of myocardium inflammatory cells, accompanied by degeneration and necrosis of adjacent myocardial cells. . In 1991, Lieberman divided myocarditis into fulminant myocarditis, acute myocarditis, chronic active myocarditis and chronic persistent myocarditis according to the histological changes and clinical manifestations of myocardial biopsy. The clinical manifestations of myocarditis are diverse, ranging from asymptomatic to severe arrhythmia, acute cardiac insufficiency, cardiogenic shock and even death. Endomyocardial tissue biopsy is the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/05A61K9/20A61P9/00A61K31/245A61K36/8968
CPCA61K31/245A61K9/20A61K36/232A61K36/484A61K36/69A61K36/88A61K36/8968A61K38/05A61K2236/33A61K2236/39A61K2236/51A61P9/00A61K2300/00
Inventor 何凤姣
Owner 何凤姣
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