Optical tomography reconstruction method based on iterative measurement

A technology of optical tomography and iterative measurement, which is applied in diagnostic recording/measurement, diagnosis using tomography, diagnosis, etc. It can solve the problems of increased matrix size, large imaging error, and inapplicable diffusion equation, etc., to improve modeling accuracy , reduced computational cost, and high reconstruction speed

Pending Publication Date: 2018-12-25
SUZHOU UNIV
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Problems solved by technology

But the diffusion approximation has inherent limitations: first, for regions where the medium is low scattering or non-scattering, the diffusion equation does not apply
However, this leads to an increase in the size of the matrix, which increases the computational cost of the reconstruction
Using the method of simplifying the model, the dimen

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  • Optical tomography reconstruction method based on iterative measurement
  • Optical tomography reconstruction method based on iterative measurement
  • Optical tomography reconstruction method based on iterative measurement

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[0030] Examples:

[0031] Such as figure 1 As shown, the optical tomographic reconstruction method based on iterative measurement includes:

[0032] The integration of forward model errors is used to compensate for the forward model errors caused by diffusion approximation, thereby improving the modeling accuracy of the optical transmission process;

[0033] The grouping iteration of measurement data is used to reduce the amount of reconstruction calculation and improve the reconstruction speed.

[0034] Step 1. The integration of forward model errors includes:

[0035] 1) Use Gaussian model to represent the forward model error ε, Among them, N represents Gaussian distribution, Γ ε with Represent the covariance and mean of the forward model error ε, respectively. Use Gaussian model to represent the absorption coefficient x to be reconstructed, Among them, Γ x with Denote the covariance and mean of x, respectively.

[0036] 2) Generate a set of samples x according to the Gaussian mo...

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Abstract

The invention discloses an optical tomography reconstruction method based on iterative measurement, which divides the boundary measurement data into two groups. In the iterative reconstruction process, the two groups of boundary measurement data are alternately used for iterative reconstruction until the value of the objective function is smaller than a preset threshold value, and the final absorption coefficient to be reconstructed is obtained. The forward model error between radiative transfer equation and diffusion approximation is incorporated into the imaging process, so that the forwardmodel error caused by diffusion approximation can be compensated, and the modeling accuracy and imaging speed of the optical transmission process can be improved.

Description

technical field [0001] The invention belongs to the technical field of biological optical imaging, in particular to an optical tomography reconstruction method based on iterative measurement. Background technique [0002] Optical tomography is a very important imaging method in biomedical research, and it is a highly sensitive non-destructive detection technology. This technology can be used to image the optical parameters such as absorption coefficient and scattering coefficient of various parts of biological tissues, so as to provide important functional information of biological tissues, which has broad development prospects and research value. Its notable features include: non-invasive, portability, continuity, functional measurement. At present, this technology has been successfully applied in blood oxygen detection, early diagnosis and location of cerebral hemorrhage, detection of breast cancer and other fields. [0003] Optical tomographic image reconstruction inclu...

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Application Information

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IPC IPC(8): G06T11/00G06F17/50A61B5/00
CPCA61B5/0073G06T11/005G06F30/23
Inventor 邹玮
Owner SUZHOU UNIV
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