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Hypoglycemic composition and preparation method thereof

A composition and hypoglycemic technology, which is applied in the field of biomedicine, can solve the problems such as difficult control of the content of active ingredients, and achieve the effect of protecting the efficacy of pancreatic islet β cells, overcoming the difficulty of controlling the content, and reversing the development process

Inactive Publication Date: 2019-02-15
湘潭市中心医院
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

The active ingredients in the hypoglycemic composition are extracted from traditional Chinese medicines, aiming to inherit the advantages of multi-components, multi-targets, and multi-action pathways of the compatibility of traditional Chinese medicine decoction pieces, and overcome the disadvantage that the content of active ingredients in the compatibility of traditional Chinese medicine decoction pieces is not easy to control

Method used

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  • Hypoglycemic composition and preparation method thereof
  • Hypoglycemic composition and preparation method thereof
  • Hypoglycemic composition and preparation method thereof

Examples

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Embodiment 1

[0039] This embodiment provides a hypoglycemic composition, which includes the following ingredients in parts by weight: 5-20 parts of total alkaloids of mulberry leaves, 40-60 parts of total flavonoids of kudzu root, 45-70 parts of bitter melon glycosides and 45-70 parts of Yam polysaccharides.

[0040] Wherein, the total alkaloids of mulberry leaves specifically refers to a mixture of some or all of the various alkaloids contained in mulberry leaves. 1-deoxynojirimycin (1-DNJ) is one of the multiple alkaloids of mulberry leaves, and the quality of 1-deoxynojirimycin is preferably not less than 10% of the total mass of the total alkaloids of mulberry leaves. At this time, the hypoglycemic effect of the hypoglycemic composition is even better.

[0041] Wherein, the total flavonoids of Pueraria lobata specifically refers to a mixture of some or all of the various flavonoids contained in Pueraria lobata. Puerarin is one of the various flavonoids of Pueraria radiata, and the qu...

Embodiment 2

[0082] This embodiment provides a method for preparing a hypoglycemic composition, which mainly includes the following steps:

[0083] S101. extracting the total alkaloids of mulberry leaves from mulberry leaves, and making the obtained total alkaloids of mulberry leaves into powder;

[0084] S102. Extracting the total flavonoids of Pueraria lobata from Pueraria lobata, and making the total flavonoids of Pueraria lobata into powder;

[0085] S103. Extracting Momordica glycosides from Momordica charantia, and making the obtained Momordica glycosides into powder;

[0086] S104. extracting yam polysaccharide from yam, and making the obtained yam polysaccharide into powder;

[0087]S105. Combine 5-20 parts by weight of powdered total alkaloids of mulberry leaves, 40-60 parts by weight of powdered total flavonoids of kudzu root, 45-70 parts by weight of The powdered yam polysaccharide is mixed to obtain the hypoglycemic composition.

[0088] It should be understood that the orde...

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Abstract

The invention relates to the technical field of biological medicines, provides a hypoglycemic composition and a preparation method thereof, aims to inherit the advantages of multiple components, multiple targets, multiple action pathways and the like in the compatibility of traditional Chinese Medicine decoction pieces and also overcomes the defect that active ingredients in the compatibility of the traditional Chinese Medicine decoction pieces are hard to control. The hypoglycemic composition comprises the following components in part by weight: 5-20 parts of folium mori total alkaloids, 40-60 parts of radix puerariae total flavonoids, 45-70 parts of charantin and 45-70 parts of Chinese yam polysaccharide. The preparation method of the hypoglycemic composition comprises the following steps: respectively extracting from folium mori, radix puerariae, bitter gourd and Chinese yam to prepare the powdery folium mori total alkaloids, the powdery radix puerariae total flavonoids, the powderycharantin and the powdery Chinese yam polysaccharide; then mixing according to a certain weight ratio to obtain the hypoglycemic composition. All the components of the hypoglycemic composition are definite and specific in content and obtained by extracting the traditional Chinese medicines, and a hypoglycemic effect of the hypoglycemic composition is better than that of a water extract or an alcohol extract compatible with a raw decoction piece.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a hypoglycemic composition and a preparation method thereof. Background technique [0002] Type 2 diabetes mellitus (type 2diabetes mellitus, T2DM) has attracted widespread attention worldwide due to its high incidence and refractory nature. Although the T2DM chemical drugs currently used clinically have significant hypoglycemic effects, they cannot reverse the course of the disease, and their targets are single. Long-term use will lead to drug resistance and even side effects. Traditional Chinese medicine has obvious advantages in the treatment of complex diseases (such as diabetes, senile dementia, etc.) due to its characteristics of multi-component, multi-target and multi-action pathway. [0003] However, the compatibility of traditional Chinese medicine decoction pieces also has insurmountable shortcomings, which are mainly reflected in the fact that the active ingredien...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/605A61P3/10A61K31/704A61K31/715
CPCA61K31/704A61K31/715A61K36/488A61K36/605A61P3/10A61K2300/00
Inventor 邢琪昌
Owner 湘潭市中心医院
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