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Heparinoid composition-containing plaster

A composition and plaster technology, applied in the field of plaster containing heparin-like composition, can solve problems such as imperfect application of heparin-like composition, achieve the effect of inhibiting the reproduction of smooth muscle cells, curing edema and edema, and improving local microcirculation. Effect

Inactive Publication Date: 2019-03-15
沈阳亿欣源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the prior art, the application of the heparinoid composition on the skin, mucous membrane and other action sites is not perfect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1; A patch containing a heparin composition, comprising 40 parts of heparin, 1 part of sodium carboxymethyl cellulose, 0.1 part of dimethyl sulfoxide, 0.1 part of vitamin C, 0.18 part of preservative, and collagen 0.5 part of protein, 0.1 part of xanthan gum, 0.1 part of potassium sorbate, 3 parts of glycerin, 0.1 part of fatty alcohol sodium sulfate.

Embodiment 2

[0030] Example 2; A patch containing a heparin composition, comprising 20 parts of heparin, 1.25 parts of sodium carboxymethyl cellulose, 1 part of dimethyl sulfoxide, 0.125 parts of vitamin C, 2 parts of preservatives, collagen 5 parts of protein, 10 parts of xanthan gum, 0.125 parts of potassium sorbate, 10 parts of glycerin, 2.5 parts of fatty alcohol sodium sulfate.

Embodiment 3

[0031] Example 3; A patch containing a heparin composition, comprising 0.5 parts of heparin, 1.5 parts of sodium carboxymethyl cellulose, 2 parts of dimethyl sulfoxide, 0.2 parts of vitamin C, 5 parts of preservatives, and collagen 5 parts of protein, 20 parts of xanthan gum, 0.2 parts of potassium sorbate, 15 parts of glycerin, 5 parts of fatty alcohol sodium sulfate.

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PUM

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Abstract

The invention discloses a heparinoid composition-containing plaster and belongs to the technical field of biology. The heparinoid composition-containing plaster is characterized by comprising 0.01-80parts of mucopolysaccharide, 1-90 parts of a host material, 0.01-5 parts of a transdermal absorbent, 0.01-5 parts of an antioxidant, 0.01-5 parts of a preservative, 0.01-5 parts of a humectant, 0.1-20parts of a thickener, 0.01-5 parts of a bacteriostatic agent, 0.01-15 parts of a surfactant, and 0.01-5 parts of an emulsifier. Under the synergistic effects of a cutin softener and the natural humectant, the excessive growth of a collagenous fiber is inhibited, the formation of a scar is alleviated; the moisture on the surface of the skin is retained, the collagenous fiber is softened, the elasticity is strengthened, and the heparinoid composition-containing plaster has a softening effect on the hypertrophic scar.

Description

Technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a patch containing heparin-like composition used in medicines, medical equipment, cosmetics, disinfection products and the like. Background technique [0002] Heparinoid is a kind of mucopolysaccharide. In 1948, when Jorpes and Gardell prepared heparin from liver and lung, they obtained a polysaccharide composed of D-glucuronic acid and D-glucosamine. These substances are similar in structure to heparin. , But the degree of sulfation is low and the anticoagulant activity is low, but after polysulfation, its properties have changed greatly. By binding to the surface of the vascular endothelium, it promotes the release of endogenous amino polysaccharides with antithrombotic activity, which can improve local microcirculation, increase blood flow and blood flow speed, thereby improving intermediate metabolism, promoting skin nutrient supply and waste excretion It has the effects ...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K31/727A61K31/737A61P7/10A61P9/14A61P17/02A61P29/00A61P31/02A61P31/04A61P31/10A61P31/14
CPCA61K31/727A61K9/703A61K31/737A61P7/10A61P9/14A61P17/02A61P29/00A61P31/02A61P31/04A61P31/10A61P31/14
Inventor 唐财坤李丹关云成满国荣朱凯月肖秀梅马立强
Owner 沈阳亿欣源生物科技有限公司
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