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Pectin hydrogel dressing for wound ulcer repair and preparation method of dressing

A hydrogel and pectin technology, applied in medical science, bandages, etc., can solve the problems of poor medicinal efficacy and slow healing effect, and achieve the effects of accelerating growth, good repairing effect, and regulating wound ulcers

Inactive Publication Date: 2019-03-19
上海兰明食品科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When it is necessary to heal seriously damaged wounds such as ulcers, the current hydrogel dressings are difficult to achieve rapid healing and repair effects, and their healing effects are slow and their medicinal efficacy is poor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A pectin hydrogel dressing for wound and ulcer repair, the pectin hydrogel dressing is made of the following raw materials in parts by weight: pectin: 35 parts, chitosan: 5 parts, vitamin E: 4 parts, repair Essence: 4 parts, collagen: 2 parts, amino acid: 2 parts, hyaluronic acid: 1 part, sulfur: 2 parts, vitamin B3: 2 parts, cross-linking agent: 1 part.

[0027] The preparation method of described pectin hydrogel dressing comprises the following steps:

[0028] (1) After mixing pectin and chitosan, add 2-4 times the volume of deionized water in an ultrasonic oscillator, and after heating up, ultrasonically vibrate for a period of time to obtain a pectin hydrogel base liquid for subsequent use;

[0029] (2) Pour the pectin hydrogel base solution in the above step (1) into a blender, then add a crosslinking agent, heat up and heat for a period of time while stirring to obtain the pectin hydrogel stock solution for subsequent use;

[0030] (3) Mix vitamin E, repairing es...

Embodiment 2

[0035] A pectin hydrogel dressing for wound and ulcer repair, the pectin hydrogel dressing is made of the following raw materials in parts by weight: pectin: 40 parts, chitosan: 10 parts, vitamin E: 5 parts, repair Essence: 5 parts, collagen: 3 parts, amino acid: 3 parts, hyaluronic acid: 1.5 parts, sulfur: 3 parts, vitamin B3: 3 parts, cross-linking agent: 1.5 parts.

[0036] The preparation method of described pectin hydrogel dressing comprises the following steps:

[0037] (1) After mixing pectin and chitosan, add 2-4 times the volume of deionized water in an ultrasonic oscillator, and after heating up, ultrasonically vibrate for a period of time to obtain a pectin hydrogel base liquid for subsequent use;

[0038] (2) Pour the pectin hydrogel base solution in the above step (1) into a blender, then add a crosslinking agent, heat up and heat for a period of time while stirring to obtain the pectin hydrogel stock solution for subsequent use;

[0039] (3) Mix vitamin E, repai...

Embodiment 3

[0044] A pectin hydrogel dressing for wound and ulcer repair, the pectin hydrogel dressing is made of the following raw materials in parts by weight: pectin: 45 parts, chitosan: 15 parts, vitamin E: 6 parts, repair Essence: 6 parts, collagen: 4 parts, amino acid: 4 parts, hyaluronic acid: 2 parts, sulfur: 4 parts, vitamin B3: 4 parts, cross-linking agent: 2 parts.

[0045] The preparation method of described pectin hydrogel dressing comprises the following steps:

[0046] (1) After mixing pectin and chitosan, add 2-4 times the volume of deionized water in an ultrasonic oscillator, and after heating up, ultrasonically vibrate for a period of time to obtain a pectin hydrogel base liquid for subsequent use;

[0047] (2) Pour the pectin hydrogel base solution in the above step (1) into a blender, then add a crosslinking agent, heat up and heat for a period of time while stirring to obtain the pectin hydrogel stock solution for subsequent use;

[0048] (3) Mix vitamin E, repairing...

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Abstract

The invention provides a pectin hydrogel dressing for wound ulcer repair and a preparation method of the dressing, and relates to the technical field of pharmaceutical production. The pectin hydrogeldressing is prepared from the following raw materials in parts by weight: 35-45 parts of pectin, 5-15 parts of chitosan, 4-6 parts of vitamin E, 4-6 parts of repair essence, 2-4 parts of collagen, 2-4parts of amino acid, 1-2 parts of hyaluronic acid, 2-4 parts of sulfur, 2-4 parts of vitamin B3 and 1-2 parts of cross-linking agents. The dressing overcomes the defects in the prior art, and thus the healing speed and healing effect of the hydrogel dressing can be effectively improved, the inflammation and swelling can be rapidly diminished, the wound ulcer is adjusted and the healing is promoted, the growth of newborn epithelium and granulation tissue is accelerated, the healing effect is good, and bacteria can be effectively resisted, so that the dressing is suitable for popularization.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical production, in particular to a pectin hydrogel dressing for wound ulcer repair and a preparation method thereof. Background technique [0002] Hydrogel dressing is a new type of wound dressing developed in recent years. Compared with traditional dressings, hydrogel can promote wound healing and reduce pain for patients. It can improve the microenvironment of the wound and inhibit the growth of bacteria. Hydrogel is especially suitable for common body surface trauma, such as abrasions, scratches, bedsores and other skin injuries. [0003] Pectin is a natural polymer compound with good gelation and emulsification stability, and has been widely used in food, medicine, daily chemical and textile industries. In the medical field, pectin has the effect of protecting the skin and accelerating wound healing. [0004] The current hydrogel dressing is usually prepared with sodium alginate as the m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0004A61L26/0023A61L26/0033A61L26/0057A61L26/0066A61L26/008A61L2300/30A61L2300/404A61L2300/41A61L2300/412C08L5/06C08L5/08
Inventor 谢保明刘革兰
Owner 上海兰明食品科技有限公司
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