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Tyrosinase inhibitor, and whitening blemish balm and preparation method thereof

A tyrosinase and inhibitor technology, applied in the fields of tyrosinase inhibitors, whitening creams and their preparation, can solve the problems of poor tyrosinase inhibitory effect and the like, and achieve excellent inhibitory effect, inhibitory activity, Formulated for mild effect

Active Publication Date: 2019-03-29
GUANGZHOU KENENG COSMETICS RES CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of the poor effect of the Chinese herbal medicine whitening and freckle-removing preparations in the prior art, and the problems such as poor tyrosinase inhibitory effect, the present invention firstly provides a tyrosinase inhibitor

Method used

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  • Tyrosinase inhibitor, and whitening blemish balm and preparation method thereof
  • Tyrosinase inhibitor, and whitening blemish balm and preparation method thereof
  • Tyrosinase inhibitor, and whitening blemish balm and preparation method thereof

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Effect test

no. 1 approach

[0035] The first embodiment of the present invention provides a tyrosinase inhibitor, comprising: kudzu root extract and peppermint extract. Based on the total mass of the tyrosinase inhibitor, the added amount of the kudzu root extract is 0.1-55%, and the added amount of the peppermint extract is 45-99.9%. The tyrosinase inhibitor of the present invention can well inhibit the activity of tyrosinase, and has excellent whitening effect when used in cosmetics, especially in whitening and repairing creams.

[0036] Pueraria lobata (wild) Ohwi is the dry root of Pueraria lobata (wild) Ohwi or Puerariathomsonil Benth, which is also known as Pueraria lobata (wild) Ohwi. There are 11 species of Pueraria in my country, and except for Pueraria kudzu which is mainly cultivated artificially, the rest are mainly wild. The Chinese Pharmacopoeia (1990 edition) recorded two original plants of the genus Pueraria mirifica and Pueraria pueraria.

[0037] The main components of kudzu root are:...

no. 2 approach

[0044] The second embodiment of the present invention provides a whitening and repairing cream, including the tyrosinase inhibitor of the first embodiment of the present invention, based on the total mass of the whitening and repairing cream, the tyrosinase inhibitor The addition amount of agent is 0.01-10%. In the present invention, by adding the tyrosinase inhibitor of the present invention, the activity of tyrosinase can be inhibited, thereby achieving an excellent whitening effect.

[0045] The whitening and repairing cream of the present invention also includes: moisturizing agent, grease, thickener, emulsifier, pH regulator, skin conditioner, sensitizer and antioxidant; The formula composition of whitening and repairing cream of the present invention is gentle, can The effect of the tyrosinase inhibitor of the present invention can be brought into full play. in particular:

[0046] Wherein, based on the total mass of the whitening and repairing cream, the added amount ...

no. 3 approach

[0072] The third embodiment of the present invention provides a preparation method of the whitening and repairing cream according to the second embodiment, including the step of mixing the components of the whitening and repairing cream.

[0073] Specifically, the preparation method of described whitening and repairing cream comprises the following steps:

[0074] 1. Add oil, emulsifier, part of thickener, stimulant, antioxidant, part of preservative, and fragrance into the emulsification pot, stir and heat to 80-85°C to fully dissolve;

[0075] 2. Add water, moisturizer, part of the skin conditioning agent, the remaining thickener, pH regulator, and optional chelating agent into the water phase pot, stir and heat to 80-85°C to fully dissolve;

[0076] 3. Slowly pump the water phase material in the water phase pot to the emulsification pot, stir, homogenize, and vacuum emulsify, and keep the temperature of the emulsification pot at 80-85°C;

[0077] 4. Cool down to 40-50°C, a...

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Abstract

The invention provides a tyrosinase inhibitor, and whitening blemish balm and a preparation method thereof. The tyrosinase inhibitor comprises an extract of dried roots of pueraria lobata (wild) ohwior pueraria thomsonil Benth, and a mentha haplocalyx Briq extract, based on the total mass of the tyrosinase inhibitor, the addition quantity of the extract of dried roots of pueraria lobata (wild) ohwi or pueraria thomsonil Benth is 0.1-55%, and the addition quantity of the mentha haplocalyx Briq extract is 45-99.9%. The tyrosinase inhibitor disclosed by the invention is excellent in the effect of restraining the activity of tyrosinase, and does not have any side effects on human bodies. Further, the formula of the whitening blemish balm disclosed by the invention is mild, the activity of thetyrosinase can be effectively restrained, and the whitening effect can be achieved.

Description

technical field [0001] The invention relates to a tyrosinase inhibitor, a whitening and repairing cream and a preparation method thereof, belonging to the field of cosmetics. Background technique [0002] Melanin is mainly produced by melanocytes in the basal layer of human skin epidermis, which can reduce the damage of ultraviolet rays to the skin. The content and distribution of melanin determine the color of the skin. However, the abnormal accumulation of melanin in the basal layer will cause hyperpigmentation and cause melasma, freckles, age spots, etc., affecting people's quality of life. With the deepening of research on melanin biosynthesis, researchers found that tyrosinase (tyrosinase) plays an important role in melanin biosynthesis, and it is the main rate-limiting enzyme in the process of converting tyrosine and dopa to melanin. The overexpression of is the main cause of hyperpigmentation. Therefore, inhibiting the activity of tyrosinase can block the biosynthe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/81A61K8/31A61K8/49A61K8/73A61K8/65A61K8/9711A61K8/64A61K8/34A61K8/9794A61Q19/02A61Q19/00
CPCA61Q19/00A61Q19/02A61K8/31A61K8/34A61K8/4946A61K8/4993A61K8/64A61K8/65A61K8/73A61K8/8158A61K8/9711A61K8/9789A61K8/9794A61K2800/48A61K2800/782A61K2800/5922
Inventor 杨登亮刘德海戴嘉彬江兰兰李华真林盛杰张伟杰张楚标
Owner GUANGZHOU KENENG COSMETICS RES CO LTD
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