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Rhizoma dioscoreae formula granules and preparation method thereof

A technology for formula granules and diospyross sativa, which is applied in the field of formula granules of diospyross sativa and its preparation, and achieves the effects of convenient administration, uniform particle size, and easy industrialization.

Inactive Publication Date: 2019-04-05
JIANGXI GROUNDIONG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the formula granules and preparation technology of yam yam

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0021] The preparation method of the yam yam formula granule of the present invention comprises the following steps:

[0022] (1) pulverizing yam yam into particles with a particle size of 40-100 mesh;

[0023] (2) mixing the yam granules obtained in step (1) with the ethanol aqueous solution, wherein the volume ratio of the yam granules to the ethanol solution is 1:7-12;

[0024] (3) Heat and decoct for 1-3 hours, filter;

[0025] (4) the filtrate is concentrated under reduced pressure to a concentrated solution whose relative density is 1.1-1.2;

[0026] (5) Mix the concentrated solution with pharmaceutically acceptable adjuvants, dry, and collect dry cream powder;

[0027] (6) Pulverize the dry cream powder, cross 80 mesh sieves, and mix in a mixing tank;

[0028] (7) The yam powder obtained in the step (6) is granulated, and the granules are sequentially sized with a 20-mesh sieve and a 50-mesh sieve to obtain the yam powder formula granules.

[0029] In step (1), the ...

Embodiment 1

[0044] (1) Get 1kg of yam, grind it to a particle size of 80 mesh, add 10 times the amount of ethanol aqueous solution (concentration is 45% by weight), heat to 85°C and decoct for 2 hours, filter with a 200 mesh stainless steel screen, and the filtrate Concentrated under pressure to a concentrated solution with a relative density of 1.15;

[0045] (2) Add 100g of a mixture of starch, lactose and dextrin (the weight ratio of the three is 1:0.25:1) to the concentrated solution for mixing, freeze-dry, collect the dry cream powder, crush it through an 80-mesh sieve, and mix it in a mixing tank ;

[0046] (3) Take yam yam cream powder, sieve and granulate, and granulate the granules with a 20-mesh sieve and a 50-mesh sieve in turn to obtain yam yam formula granule sample A1.

Embodiment 2

[0048] (1) Get 1kg of yam, crush it to a particle size of 40 mesh, add 12 times the amount of ethanol aqueous solution (concentration is 30% by weight), heat to 90 ° C for 1 hour, filter with 200 mesh stainless steel wire mesh, and the filtrate Concentrated under pressure to a concentrated solution with a relative density of 1.1;

[0049] (2) Add 80g of a mixture of starch, lactose and dextrin (the weight ratio of the three is 1:0.25:1) to the concentrated solution for mixing, freeze-dry, collect the dry cream powder, crush it through an 80-mesh sieve, and mix it in a mixing tank ;

[0050] (3) Take yam yam cream powder, sieve and granulate, and granulate the granules with a 20-mesh sieve and a 50-mesh sieve in turn to obtain yam yam formula granule sample A2.

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Abstract

The invention relates to the technical field of traditional Chinese medicine formula granules and discloses rhizoma dioscoreae formula granules and a preparation method thereof. The method comprises the following steps: (1) crushing rhizoma dioscoreae into granules with the granularity of 40 to 100 meshes; (2) mixing the rhizoma dioscoreae granules obtained by step (1) and an ethanol water solution, wherein the volume ratio of the rhizoma dioscoreae granules to the ethanol water solution is 1 to (7 to 12); (3) heating and decocting for 1 to 3 h, and filtering; (4) performing vacuum concentration on the filtrate to obtain a concentrated solution with the relative density of 1.1 to 1.2; (5) mixing the concentrated solution and pharmaceutically acceptable auxiliary materials; drying and collecting dry paste powder; (6) crushing the dry paste powder and sieving through a sieve with the size of 80 meshes; mixing in a mixing groove; (7) granulating prepared rhizoma dioscoreae powder and sieving the granules through a sieve with the size of 20 meshes and a sieve with the size of 50 meshes sequentially. The rhizoma dioscoreae formula granules prepared by the method provided by the invention have relatively high active component content and the size of the granules is uniform.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine formula granules, in particular to a yam yam formula granule and a preparation method thereof. Background technique [0002] Traditional Chinese medicine formula granules are obtained by extracting, separating, concentrating, drying, granulating and packaging the whole ingredients of the medicinal materials through modern processing technology and pharmaceutical technology. They can be directly formulated and packaged without decoction. Granules for ingestion. Traditional Chinese medicine formula granules not only retain the active ingredients, indications and efficacy of traditional Chinese medicine decoction pieces, but also have the advantages that decoction pieces do not have, such as unified standard, stable curative effect, convenient carrying and easy adjustment. Over-the-counter supplements. [0003] Dioscorea cirrhosa Lour. is a vine belonging to the family Dioscore...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/16
CPCA61K9/1652A61K36/8945A61K2236/333A61K2236/51
Inventor 廖年生邹明明眭荣春陈小燕
Owner JIANGXI GROUNDIONG PHARM CO LTD
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