Application of polygonum sinense polysaccharide to preparation of drugs for preventing and treating viral pneumonia

A technology of viral pneumonia and fotanmu, which is applied in the direction of antiviral agents, drug combinations, and pharmaceutical formulas, can solve the problems of drug efficacy and drug research on acute pneumonia of fotanmu polysaccharides that have not been reported
CN109589352AActive Publication Date: 2019-04-09FUDAN UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
FUDAN UNIV
Publication Date
2019-04-09

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Abstract

The invention belongs to the field of traditional Chinese medicine, and particularly relates to application of polygonum sinense polysaccharide to preparation of drugs for preventing and treating viral pneumonia. Total polysaccharide extractive is obtained in traditional Chinese medicine polygonum sinense through separation and extraction, the average yield is greater than 2 percent, and the polysaccharide content is greater than 60 percent. Experiment results show that polygonum sinense polysaccharide extractive can inhibit the release of proinflammatory factors, promote the release of anti-inflammatory factors, reduce pulmonary capillary permeability, reduce pneumorrhagia and pulmonary edema, and inhibit systemic or pulmonary local inflammation reaction, thereby reducing acute lung injury; and a whole experiment show that the polygonum sinense polysaccharide extractive has an obvious inhibiting effect on mice acute pneumonia induced by influenza virus a H1N1. The polygonum sinense polysaccharide can be further applied to preparation of drugs for preventing and treating viral pneumonia.
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Description

Technical field:

[0001] The invention belongs to the field of traditional Chinese medicine and relates to a new medicinal application of the traditional Chinese medicine Futanmu polysaccharide. It specifically relates to the use of Fotanmu polysaccharide in the preparation of medicines for preventing and treating viral pneumonia. Background technique:

[0002] Studies have reported that viral pneumonia (vital pneumonia) is lung inflammation caused by a variety of viral infections, usually caused by the downward spread of upper respiratory tract viral infection. According to reports, influenza virus is the most common virus causing pneumonia, and also includes parainfluenza virus, cytomegalovirus, adenovirus, rhinovirus, coronavirus and some enteroviruses; influenza A virus is the cause of respiratory diseases in humans and birds Influenza virus invades the bronchiole epithelium and causes bronchiolitis, and the infection spreads to the interstitium and alveoli, causing pneu...

Claims

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