Method for extracting, separating and purifying lyciumbarbarum polysaccharide, lyciumbarbarumglycopeptide and hypoglycemic medicament

A technology of Lycium barbarum polysaccharide and purification method, applied in the directions of glycopeptide components, drug combinations, peptides, etc., can solve the problems of less than 1% yield of Lycium barbarum, unstable process, uncertain product structure, etc., so as to prevent genetic damage and enhance hematopoiesis. function, the effect of enhancing immunity

Pending Publication Date: 2019-04-16
EAST CHINA UNIV OF SCI & TECH
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Problems solved by technology

Lycium barbarum polysaccharide is a water-soluble polysaccharide, which is the most important active ingredient in wolfberry, with a relative molecular mass of 68-200; Lycium barbarum polysaccharide is one of the main active ingredients in wolfberry, which has the functions of enhancing immunity, anti-aging, enhancing hematopoietic function, To prevent genetic damage and other effects, most of the prior art utilizes the crude product of Lycium barbarum polysaccharide; the purification method of the current existing technology is to use the traditional alcohol precipitation water extraction process, resulting in a yield of less than 1% for purified Lycium barbarum products, Moreover, the complex structure of the mixture cannot obtain a product that satisfies efficacy
[0004] (1) The purification methods of the existing technology all use the traditional alcohol precipitation and water extraction process, resulting in a yield of less than 1% for purified wolfberry products, and the structure of the mixture is complex, and products with satisfactory efficacy cannot be obtained;
[0005] (2) The process of the prior art is unstable, the structure of the product obtained each time is uncertain, the test results vary widely each time, and the yield is very low

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  • Method for extracting, separating and purifying lyciumbarbarum polysaccharide, lyciumbarbarumglycopeptide and hypoglycemic medicament

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Embodiment Construction

[0027] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0028] In view of the prior art, all the crude products of Lycium barbarum polysaccharides are used; the extraction, separation and purification methods of Lycium barbarum polysaccharides and the analysis and research of its components and structures are rarely reported; Lycium barbarum polysaccharides have the functions of enhancing immunity, anti-aging, and enhancing hematopoiesis. Function, prevent genetic damage and so on.

[0029] The application principle of the present invention will be described in detail below in conjunction with the accompanying drawings.

[0030] Such as figure 1 As shown, the method for extrac...

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Abstract

The invention belongs to the technical filed of extraction, separation and purification; the invention discloses a method for extracting, separating and purifying lyciumbarbarum polysaccharide, lyciumbarbarumglycopeptide and a hypoglycemic medicament. The lyciumbarbarumpolysaccharide has effects in enhancing immunity, preventing aging, enhancing hematopoiesis, and preventing genetic injury; the lyceum barbarum polysaccharide (LBP) is a complex polysaccharide composed of acidic heteropolysaccharide and polypeptide or protein, and has glycopeptide structure of Glycano-O-Ser; the anti-tumor effect of the lyciumbarbarumglycopeptide is completed through an extremely complex regulation and control mode: the production of liver glycogen is inhibited by interfering the expression of related enzymes and proteins, so that the effect of reducing blood sugar is achieved. LBP has a positive effect on insulin and islet cells so as to indirectly achieve the effect of reducing blood sugar, LBP does not achieve the effect of reducing blood sugar by promoting pancreas to secrete insulin, and is a very good product for treating diabetes.

Description

technical field [0001] The invention belongs to the technical fields of extraction, separation and purification, and in particular relates to a method for extracting, separating and purifying wolfberry polysaccharides, wolfberry glycopeptides and hypoglycemic drugs. Background technique [0002] At present, the prior art commonly used in the industry is like this: the nature and flavor of wolfberry fruit are sweet and flat; the nature and flavor of wolfberry leaves are bitter and sweet; cool in nature. Functionally, wolfberry can nourish the liver, nourish the kidney and nourish the lungs. Lycium barbarum leaves have the specific effect of tonifying deficiency and benefiting essence, clearing away heat and improving eyesight. Lycium barbarum polysaccharide is a water-soluble polysaccharide, which is the most important active ingredient in wolfberry, with a relative molecular mass of 68-200; Lycium barbarum polysaccharide is one of the main active ingredients in wolfberry, w...

Claims

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Application Information

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IPC IPC(8): C12P19/14C12P19/04C07K9/00A61K38/14A61K9/20A61K9/48A61P3/10
CPCA61K38/14A61P3/10A61K9/20A61K9/48C12P19/04C12P19/14C07K9/00
Inventor 滕鑫
Owner EAST CHINA UNIV OF SCI & TECH
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