An implantable fully bioabsorbable vascular polymer scaffold

Abstract

Disclosed is an implant-type, completely bioabsorbable, vascular polymer stent comprising five or more annular corrugated support struts (1), and connecting struts (2) spaced apart and connected between the support struts (1). The support struts (1) are formed by corrugations resembling an "Ω" shape (3) and corrugations resembling an "m" shape (4) being alternately connected with each other, wherein the corrugations resembling an "Ω" shape (3) and the corrugations resembling an "m" shape (4) are respectively composed of two sets of upright "s" parts and inverted "s" parts connected together, and the connection between two adjacent support struts (1) is formed by means of the connecting struts (2) connecting the top of the corrugations resembling an "Ω" shape (3) and the bottom of the corrugations resembling an "m" shape (4). The stent balances radial supporting force, wall thickness and flexibility, has good passing-through performance, can also provide sufficient mechanical support at a lesion segment for a specified period of time for wound healing, and is be gradually absorbed by the body after the wound heals, with good endothelialisation, thereby effectively reducing the stent restenosis rate and the risk of late stent thrombosis.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to an implantable fully bioabsorbable blood vessel polymer stent. Background technique [0002] Since the first metal stent Palmaz-Schatz was implanted into the human body in 1985, stent interventional therapy has successfully solved the problem of high restenosis rate in the era of simple balloon dilatation, and has become the main method of clinical treatment. After the metal stent is implanted in the human body, it is found that the restenosis rate in the stent is still as high as about 20% due to inflammatory reactions, neointimal hyperplasia, negative vascular remodeling, and delayed endothelialization of the stent. [0003] In order to solve this problem, the first generation of polymer-coated drug-eluting stents came into being. The emergence of drug-eluting stents will reduce the restenosis after interventional treatment from 30-40% in the era of simple PTCA to 15-25% in the ...

AI Technical Summary

Problems solved by technology

However, this solution also has relatively large deficiencies in setting smaller crimping diameters, and especially in the support and stability of its sections when used in polymer stents

[0012] In addition, the tube wall thickness of the existing degradable stent is affected by the material and processing methods, which are thicker than the metal stent, which is 2 times or more than the metal stent, which increases the difficulty of endothelial cells climbing up the stent rod and wrapping it completely , making it difficult to re-endothelialize the surface of the stent, affecting the risk of stent thrombosis

[0013] At present, all kinds of fully bioabsorbable stents on the market cannot achieve the perfect unity of various technical indicators, especially the radial support force, wall thickness and flexibility of the stent

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