Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

IgY (Immunoglobulin of yolk) compound lotion for gynecological inflammation

A technology of lotion and gynecological diseases, which is applied in the field of biomedicine, can solve the problems of Gardnerella vaginitis and other problems, and achieve the effects of no drug resistance, lower recurrence rate, and better therapeutic effect

Inactive Publication Date: 2019-04-26
江苏润洁生物科技有限公司
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There are currently no medications that can treat Gardnerella vaginitis and prevent recurrence

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • IgY (Immunoglobulin of yolk) compound lotion for gynecological inflammation
  • IgY (Immunoglobulin of yolk) compound lotion for gynecological inflammation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Example 1 Anti-Gynecological Inflammation Pathogen Specific Composite IgY Antibody

[0041] 1. Antigen preparation

[0042] Trichomonas vaginalis and Gardnerella were ingested from patients with vaginitis and cultured by conventional methods.

[0043] The prepared Trichomonas vaginalis and Gardnerella were mixed in a ratio of 1:1 and pulverized by a conventional method, and placed in a "tissue masher homogenizer" at 8000-12000rpm to fully mash and stir evenly. Then add this mixture to Freund's adjuvant in a ratio of 1-10:1-10 (usually 1:1), put it into a high-speed homogenizer and homogenize at a high speed of 30,000rpm to form a water-in-oil emulsion, that is, to obtain a composite antigen.

[0044] 2. Antibody preparation

[0045] 1) Immunity:

[0046] The selected laying hens with high immune response ability are injected with the compound antigen prepared in step ① by using the immune activation method. At an interval of 7 days after the first injection, inject...

Embodiment 2

[0063] Example 2 Composition 1 for treating gynecological inflammation and the prepared compound egg yolk antibody lotion

[0064] 20g of the composite yolk antibody obtained in Example 1, 200ml of 1000ppm nano-silver water-soluble dispersion, and 1500ml of water; after mixing, adjust the pH value to 5.5±0.1 to obtain a lotion.

Embodiment 3

[0065] Example 3 Composition 2 for treating gynecological inflammation and the prepared compound egg yolk antibody lotion

[0066] 15g of the composite yolk antibody obtained in Example 1, 300ml of 1000ppm nano-silver water-soluble dispersion, and 2000ml of water; after mixing, adjust the pH value to 5.5±0.1 to obtain a lotion.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the field of biomedicines, and particularly relates to a gynecological lotion. The lotion is prepared from a compound egg yolk antibody and nano silver, wherein the compound egg yolk antibody is obtained by directly immunizing a laying hen with gardnerella vaginalis and trichomonas vaginalis as antigens. After vagina is cleaned with the lotion, high-activity antibodies forgardnerella vaginalis and trichomonas vaginalis are injected in a patient with gynecological inflammation. The compound egg yolk antibody is combined with the nano silver, and the compound egg yolk antibody and the prepared compound lotion for gynecological inflammation are of great significance in prevention, treatment and recurrence prevention after healing of gynecological diseases caused by vaginal infection.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to an immunoglobulin gynecological lotion for gynecological inflammation. Background technique [0002] Bacterial vaginosis (BV) can increase the risk of pelvic inflammatory disease in women, increase the susceptibility to sexually transmitted diseases, and lead to adverse pregnancy and other consequences. Gardnerella vaginalis (GV) is one of the important pathogens of bacterial vaginosis. Gardnerella vaginitis is a type of bacterial vaginosis, also known as Haemophilus vaginitis, is a vaginal mucosal inflammation caused by Gardnerella, which can be transmitted through sexual intercourse. [0003] Gardnerella are small, Gram-negative bacilli, often club-shaped, sometimes filamentous and polymorphic, and bipolar staining is common. 0.4--0.6 microns wide, 1--2 microns long, inactive, flagella-free, and spore-free. Many strains have capsules. In artificial cultivation, fresh ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/395A61K33/38A61P15/02A61P31/04
CPCA61K39/395A61P15/02A61P31/04A61K33/38
Inventor 庞以芹吴必杰魏勇
Owner 江苏润洁生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com