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Preparation method of foam type biomaterial film

A biomaterial and foam technology, applied in the field of biomaterial films, can solve the problems of reducing postoperative complications, inconvenient tissue repair, accelerating wound healing, etc., achieving the effects of scientific and reasonable preparation method, control of wound bleeding, and strong plasticity

Inactive Publication Date: 2019-05-14
杭州蓝朗生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the medical field, there are diseases with incomplete and damaged tissues, which require tissue repair materials to repair. Collagen sponge is a medical consumable commonly used in surgery. It can act as a filler, quickly stop bleeding, prevent adhesions, and accelerate wound healing. Complications, in neurosurgery, orthopedics, gynecology, general surgery, operating room, etc., is a kind of tissue repair materials. The existing tissue repair materials have low fluidity and low plasticity, which is not convenient for tissue repair. This method Preparation of foamed biomaterial membranes to improve this problem

Method used

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  • Preparation method of foam type biomaterial film

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Effect test

Embodiment 1

[0021] The invention provides a technical solution: a method for preparing a foam biomaterial film, comprising the following steps:

[0022] S1: Select the preparation material, the preparation material is biological material, liquid and gas, the liquid is water and phosphate buffer solution, the biological material includes collagen, hyaluronic acid, gelatin, butyl polyester, alginate and histone Several, the gas is one of non-toxic gases such as air, oxygen, nitrogen and carbon dioxide, and the effect of carbon dioxide is the best;

[0023] S2: preparing a biological material solution, mixing and stirring the biological material and the HCL solution until the mixture is stirred into uniform biological material solutions of different concentrations for later use;

[0024] S3: Neutralize the biological material solution, take a suitable size dialysis bag and boil it in water for one minute, seal one end of the dialysis bag, move the dialysis bag to the sterile operating table,...

Embodiment 2

[0028] The invention provides a technical solution: a method for preparing a foam biomaterial film, comprising the following steps:

[0029] S1: Select the preparation material, the preparation material is biological material, liquid and gas, the liquid is water and phosphate buffer solution, the biological material includes collagen, hyaluronic acid, gelatin, butyl polyester, alginate and histone Several, the gas is one of non-toxic gases such as air, oxygen, nitrogen and carbon dioxide, and the effect of carbon dioxide is the best;

[0030] S2: preparing a biological material solution, mixing and stirring the biological material and the HCL solution until the mixture is stirred into uniform biological material solutions of different concentrations for later use;

[0031] S3: Neutralize the biological material solution, take a suitable size dialysis bag and boil it in water for one minute, seal one end of the dialysis bag, move the dialysis bag to the sterile operating table,...

Embodiment 3

[0035] The invention provides a technical solution: a method for preparing a foam biomaterial film, comprising the following steps:

[0036] S1: Select the preparation material, the preparation material is biological material, liquid and gas, the liquid is water and phosphate buffer solution, the biological material includes collagen, hyaluronic acid, gelatin, butyl polyester, alginate and histone Several, the gas is one of non-toxic gases such as air, oxygen, nitrogen and carbon dioxide, and the effect of carbon dioxide is the best;

[0037] S2: preparing a biological material solution, mixing and stirring the biological material and the HCL solution until the mixture is stirred into uniform biological material solutions of different concentrations for later use;

[0038] S3: Neutralize the biological material solution, take a suitable size dialysis bag and boil it in water for one minute, seal one end of the dialysis bag, move the dialysis bag to the sterile operating table,...

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Abstract

The invention discloses a preparation method of a foam type biomaterial film. The preparation method comprises the following steps: S1, preparation materials selection, wherein the preparation materials comprise a biological material, a liquid and a gas; S2, preparation of a biological material liquid: 1-2 g of a biological material and 100 ml of an HCL liquid are taken, mixed and stirred under the temperature of 4 DEG C until the mixture is stirred to be uniform to prepare the biological material liquid of different concentrations for later use; S3, neutralization of the biological material liquid: a sizeable dialysis bag is put into water for being boiled for one minute and then one end of the dialysis bag is sealed; and S4, preparation of biological material foam. The preparation methodprovided by the invention is more scientific and reasonable; the fluidity of the biological material adopted in the foam type biomaterial film is relatively high, and the biomaterial film has high adhesion; the biological material foam has very strong plasticity, and is capable of fully filling repair positions of any shape or any size; the biological material foam can control wound bleeding andprevent adhesion and scars from forming, thereby realizing tissue repair; and the foam type biomaterial film can be applied to residual cavity filling.

Description

technical field [0001] The invention relates to the technical field of biological material membranes, in particular to a method for preparing foamed biological material membranes. Background technique [0002] In the medical field, there are diseases with incomplete and damaged tissues, which require tissue repair materials to repair. Collagen sponge is a medical consumable commonly used in surgery. It can act as a filler, quickly stop bleeding, prevent adhesions, and accelerate wound healing. Complications, in neurosurgery, orthopedics, gynecology, general surgery, operating room, etc., is a kind of tissue repair materials. The existing tissue repair materials have low fluidity and low plasticity, which is not convenient for tissue repair. This method Preparation of foam biomaterial membranes can improve this problem. Contents of the invention [0003] The purpose of the present invention is to provide a method for preparing a foamed biological material film to solve the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08J9/12C08J5/18C08L89/00C08L5/08C08L5/04C08L67/00
Inventor 郭文弘
Owner 杭州蓝朗生物技术有限公司
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