Endogenous optical signal and multi-wavelength blood flow imaging system
An imaging system and optical signal technology, applied in the field of internal optical signal and multi-wavelength blood flow imaging system, can solve the problems of fixed depth and small absorption effect, and achieve the effect of synchronous acquisition and real-time analysis
Active Publication Date: 2019-05-31
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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[0005] Traditional laser speckle blood flow imaging technology is generally realized by single-wavelength near-infrared laser, which can monitor blood flow information at a specific position and depth. , Imaging sensitive blood vessels
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[0020] Such as figure 1 As shown, an endogenous optical signal and multi-wavelength blood flow imaging system includes: a first laser 1, a second laser 2, a cold light source 3, a first switch 4, a second switch 5, a third switch 6, a first Attenuator 7, second attenuator 8, third attenuator 9, first mirror 10, half mirror 11, beam expander 12, second mirror 13, fiber coupling element 14, double helical fiber 15, Optical barrel 16 , motorized filter wheel 17 , CCD 18 , controller 19 , computer 20 and filter 25 . The software system includes: a control communication module, a blood oxygen image analysis module, and a blood flow image analysis module. The optical filter 25 of different wavelengths is installed on the electric filter wheel 17, connects controller 19 by USB interface, controller 19 can control the rotating speed and the angle of electric filter wheel 17, selects different aperture surface CCD cameras, so that To perform endogenous optical signal imaging and lase...
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The invention discloses an endogenous optical signal and multi-wavelength blood flow imaging system. The endogenous optical signal and multi-wavelength blood flow imaging system comprises a first laser, a second laser, a cold light source, a first switch, a second switch, a third switch, a first attenuator, a second attenuator, a third attenuator, a first reflector, a transflective mirror, a beamexpander, a second reflector, an optical fiber coupling element, a double-helix optical fiber, an optical lens barrel, an electric optical filter wheel, a CCD, a controller, a computer and an opticalfilter. According to the invention, multi-wavelength irradiation is used for blood flow imaging for the first time, and an image fusion algorithm is used for obtaining richer blood flow information which cannot be realized by single-wavelength irradiation. In addition, the endogenous optical signal and multi-wavelength blood flow imaging system achieves simultaneous combined measurement of an endogenous optical signal imaging system and a multi-wavelength imaging system, the two systems share the same CCD camera, and blood flow oxygen imaging in the same visual field is achieved. Finally, thesynchronous collection and real-time analysis of blood oxygen and blood flow data are realized by utilizing computer control analysis software.
Description
technical field [0001] The invention relates to the technical field of optical imaging, in particular to an imaging system for endogenous optical signals and multi-wavelength blood flow. Background technique [0002] Blood flow and blood oxygen are two vital parameters in physiology, and measuring blood flow and blood oxygen is very important for monitoring, evaluating and understanding many diseases. Laser speckle blood flow imaging technology is a commonly used blood flow monitoring technology at present. It has the advantages of real-time, all-round, high temporal and spatial resolution, and can quantitatively analyze blood flow changes. Therefore, the design and implementation of laser speckle blood flow imaging system Applications are getting more and more attention and will have great development prospects. [0003] Spectral imaging technology is a product of the combination of spectral analysis technology and image analysis technology. Accurate identification and po...
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IPC IPC(8): A61B5/00A61B5/026A61B5/145
Inventor 赵月梅李韪韬钱志余张欢王康张雅檬
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS