Method for split packaging of n-butyllithium solution

Abstract

The invention relates to a method for split packaging of the packing specification of 1 L or below of a n-butyllithium solution. The method is used for split packaging of the n-butyllithium solution in small packages, the split packaging process is carried out in an all-inert gas environment and is safe and controllable, and split-packaged products are clear and free of impurities. The method comprises the following two steps that 1, split packaging is carried out on the n-butyllithium solution, specifically, 1-1, inert gas is introduced in a suppressed mode from a gas phase (gas phase valve)of a 100 L steel cylinder containing the n-butyllithium solution, liquid flows out through the liquid phase valve, is filtered and then is connected to a glove box, split packaging is carried out in the glove box filled with the inert gas, the n-butyllithium solution is transferred into reagent bottles by virtue of pipeline transfer, and 1-2, after split packaging is completed, the reagent bottlescan be safely taken out from the glove box; and 2, n-butyllithium in a pipeline is treated, specifically, after split packaging is completed, the gas phase valve of the steel cylinder is opened for pressure relief, a split packaging valve which makes contact with the reagent bottles in the glove box are closed, argon is introduced from the right side, and the residual n-butyllithium solution in the pipeline is blown into the steel cylinder.

Description

technical field [0001] The invention relates to a packaging method for n-butyllithium solution of 1L and below packaging specifications. Background technique [0002] n-Butyllithium, an alkyl derivative of lithium. Including n-butyllithium, methyllithium, phenyllithium and the like. They are commonly used as reagents, among which n-butyllithium solution is the most commonly used. Alkyllithium can carry out addition reaction to carbonyl compound, and can also carry out replacement reaction to active hydrogen, as well as halogen-lithium exchange reaction, and its reaction performance is wider and more diverse than that of general Grignard reagents. Its metal lithium derivatives formed with various metal organic compounds are widely used in organic synthesis. [0003] The pure product is a white powder with strong reducibility, and it is easy to generate heat and burn when it meets water and oxidants. The commercial product is a solution dissolved in saturated hydrocarbons ...

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Problems solved by technology

[0004] Because the n-butyllithium solution is extremely sensitive, it is prone to hydrolysis when it encounters water and moisture. During the packaging process, if there is moisture or oxygen, it is easy to cause the product to become mixed and the color will become darker, resulting in a decrease in concentration, thereby affecting the use effect. even cause danger

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