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Medical hirudin content improving poecilobdella manillensis industrialized intensive breeding method and temporary breeding box

A technology of leech and hirudin, which is applied in the field of industrial intensive cultivation of leech, can solve the problems of ineffective therapeutic effect of Chinese patent medicine, and achieve the effects of novel process, high production level and high transportation survival rate.

Pending Publication Date: 2019-06-07
王政源
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In traditional Chinese medicine, leech is a commonly used medicine for promoting blood circulation and removing blood stasis. Many Chinese patent medicines based on leeches are popular in the market, but the curative effect of this kind of Chinese patent medicine is not obvious

Method used

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  • Medical hirudin content improving poecilobdella manillensis industrialized intensive breeding method and temporary breeding box
  • Medical hirudin content improving poecilobdella manillensis industrialized intensive breeding method and temporary breeding box
  • Medical hirudin content improving poecilobdella manillensis industrialized intensive breeding method and temporary breeding box

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Effect test

Embodiment 1

[0023] Embodiment 1: a kind of method for the industrialized intensive cultivation of Hirudo phenanthrene that improves medical hirudin content, comprises the following steps,

[0024] The first step is to catch the Hirudo phenatinae with a growth period of 1 to 3 years from the nature, select the Hirudo phenanthae with a size of more than 4 grams, and clean it in clean water for 1-6 days;

[0025] In the second step, divide the phenanthrenes after cleaning into five groups according to their gram weights, namely a group of 4 to 5.9 grams, a group of 6 to 7.9 grams, and a group of 8 to 9.9 grams. A group of leeches and a group of Hirudo phenanthrene weighing more than 10 grams;

[0026] The third step is to put the grouped Hirudo phenanthae into containers with 10kg of purified water in proportion, and place them in the industrialized intensive cultivation workshop. The temperature in the workshop is kept at 20-35°C; 4-5.9 grams of them The number of leeches is 100-200, the n...

Embodiment 2

[0031] Embodiment 2: as attached figure 1 , figure 2 As shown, a special temporary storage box for placing medical live Hirudo phenatus is made of plastic, and the temporary storage box includes a rectangular box body 1 and a box cover 2, and the box body 1 is separated by a grid 3 It is divided into 4 compartments, and one Hirudo phenanthae is placed in each compartment. It is a one-month dosage when used for the treatment of Hirudo phenanthae in living body, and a living Hirudo phenanthae is used every week. The lid 2 is provided with several rows of Stomata 4, the box body is provided with a moisturizing sponge layer 5. Wherein, the box body 1 and the box cover 2 are closed by interference, so that the box cover 2 can be opened or closed.

Embodiment 3

[0032] Embodiment 3: Another kind of special-purpose temporary raising box for placing medical live bilruta phenanthae is made of aluminum alloy. The temporary raising box includes a circular box body and a box cover, and the box body is formed by a grid interval. There are 8 compartments, and a moisturizing cotton cloth layer is arranged in the box body. Wherein the opening and closing connection structure is used between the box body and the box cover to realize opening or closing of the box cover 2 . Others are identical with embodiment 2.

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Abstract

The invention discloses a medical hirudin content improving poecilobdella manillensis industrialized intensive breeding method and a temporary breeding box. The medical hirudin content improving poecilobdella manillensis industrialized intensive breeding method comprises the following steps of cleanly breeding poecilobdella manillensis weighing more than 4 grams, dividing the cleanly bred poecilobdella manillensis by gram weight into five groups, proportionally intensively culturing the poecilobdella manillensis in a container containing 10 kg of purified water for 3-6 months, cleaning and nursing the poecilobdella manillensis every day to increase the content of hirudin in the poecilobdella manillensis to 300-900 ATU / G, and loading the poecilobdella manillensis into the special temporarybreeding box for standby application or transportation. The temporary breeding box is composed of a box body and a box cover, the inside of the box body is separated into 4-8 cells by a grating, the box cover is provided with exhaust holes, and the inside of the box body is provided with a moisturizing layer. The medical hirudin content improving poecilobdella manillensis industrialized intensivebreeding method is novel in process, low in cost, high in industrialization degree, free from limitations such as weather and place and applicable to scale production. The living poecilobdella manillensis can be transported by the special temporary breeding box as the carrier and directly applied to living body therapy in Chinese medical clinics; freeze-dried poecilobdella manillensis products canbetter meet the requirements of modern biological characteristic pharmaceutical factories on quality.

Description

technical field [0001] The invention relates to a method for cultivating Hirudo phenatus, in particular to a method for industrialized intensive cultivation of Hirudo phenatus and a temporary breeding box for increasing the content of medical hirudin. Background technique [0002] At present, there are more than 100 kinds of leech resources in my country. Among the known substances in the world, in terms of removing blood garbage, anticoagulation, dissolving thrombus, and dredging microcirculation, modern biological research has found that the saliva and body of the genus phenanthrene contain a large amount of analgesic enzymes. Anti-inflammatory enzymes and lysozyme, as well as many substances with medicinal effects. It is precisely because of the role of these biologically active substances that when people are bitten by leeches, they will not feel pain, will not be infected, and the blood cannot automatically coagulate. It is the natural first choice, and at the same ti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K61/40A01K63/00
Inventor 王政源
Owner 王政源
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