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Special-medical-use formula food fat component formula for inflammatory bowel diseases, and preparation method

A technology for formula food and inflammatory bowel disease, applied in the fields of edible oil/fat, application, food science, etc., can solve the problem of rough type limitation, and achieve the effect of shortening hospitalization time, rich content and reasonable collocation

Active Publication Date: 2019-07-05
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Dietary fat intake and fat composition are important factors affecting the onset of IBD. At present, the special nutritional formula for patients with inflammatory bowel disease in the domestic market is in the initial stage of research and development. The special medical formula for patients with inflammatory bowel disease Foods have relatively rough restrictions on the amount of fat intake and the type of fat intake. How to prepare a fat formula food for special medical purposes that relieves and prevents the recurrence of inflammatory bowel disease is a technical problem to be solved in this field

Method used

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  • Special-medical-use formula food fat component formula for inflammatory bowel diseases, and preparation method
  • Special-medical-use formula food fat component formula for inflammatory bowel diseases, and preparation method
  • Special-medical-use formula food fat component formula for inflammatory bowel diseases, and preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 3

[0071] Embodiment 3 (comparative example):

[0072] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0073] Medium-chain triglycerides: 70%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0074] Nutritional oils: 5.5% linseed oil, 4.5% seabuckthorn seed oil, 6.5% olive oil, 3.5% tea seed oil, 5.5% rice bran oil, 4.5% rapeseed oil.

[0075] Preparation method is with specific embodiment 1.

[0076] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0077] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0078] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat ...

Embodiment 4

[0080] Embodiment 4 (comparative example):

[0081] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0082] Medium-chain triglycerides: 40%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0083] Nutritional oils: cottonseed oil 25%, soybean oil 18%, sunflower oil 17%.

[0084] Preparation method is with specific embodiment 1.

[0085] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0086] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0087] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat components are as follows: figure 2 .

[0088] The HE staining ...

Embodiment 5

[0089] Embodiment 5 (comparative example):

[0090] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0091] Medium-chain triglycerides: 40%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0092] Nutritional oils: peony seed oil 22%, rice bran oil 15%, corn oil 23%.

[0093] Preparation method is the same as specific embodiment 1.

[0094] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0095] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0096] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat components are as follows: figure 2 .

[0097] The HE sta...

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Abstract

The invention discloses special-medical-use fat formula food for patients suffering from inflammatory bowel diseases, and a preparation method thereof. A fat component comprises, by weight, 40% of medium chain triglyceride (the mass ratio of tricaprylin to tricaprin being 3:1), 13% of peony seed oil, 14% of camellia seed oil, 9% of corn oil, 13% of rice bran oil and 11% pf rapeseed oil. The special-medical-use fat formula food has balanced nutrient composition, reasonable fatty acid composition, MCT (medium chain triglyceride) lipids required by the patients suffering from the inflammatory bowel diseases, and rich anti-inflammatory active ingredients such as polyphenols, phytosterols and oryzanol, is easily digested and absorbed by the human body, and has remarkable relieving and protective effects on the patients suffering from the inflammatory bowel diseases.

Description

technical field [0001] The invention belongs to the technical field of formula food for special medical use, and in particular relates to a fat component formula and preparation method of formula food for special medical purpose for inflammatory bowel disease. Background technique [0002] Inflammatory bowel disease (IBD) is a chronic inflammation of the intestinal tract caused by various etiologies and mediated by abnormal immunity. ,) and ulcerative colitis (Ulcerative Colitis, UC). [0003] Malnutrition is the most common systemic manifestation in IBD patients and may occur at any stage of inflammatory bowel disease. At present, drugs such as aminosalicylic acid, glucocorticoids, and immunosuppressants are the main treatment measures for this disease, but in some cases, the efficacy of drugs is not good, and adverse drug reactions are prone to occur. Studies have shown that in the early and mid-term treatment of patients with inflammatory bowel disease, targeted nutriti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23D9/007A23D9/00
CPCA23D9/007A23D9/00
Inventor 刘睿杰郭怡雯常明张涛裘芳成金青哲王兴国
Owner JIANGNAN UNIV
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