Formula and preparation method of fat component of formula food for special medical purpose for inflammatory bowel disease

A technology for inflammatory bowel disease and formula food, applied in the direction of edible oil/fat, application, food science, etc., can solve the problem of relatively rough category limitation, shorten hospital stay, promote cholesterol dissimilation, and inhibit fat peroxidation chain reaction Effect

Active Publication Date: 2022-01-25
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Dietary fat intake and fat composition are important factors affecting the onset of IBD. At present, the special nutritional formula for patients with inflammatory bowel disease in the domestic market is in the initial stage of research and development. The special medical formula for patients with inflammatory bowel disease Foods have relatively rough restrictions on the amount of fat intake and the type of fat intake. How to prepare a fat formula food for special medical purposes that relieves and prevents the recurrence of inflammatory bowel disease is a technical problem to be solved in this field

Method used

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  • Formula and preparation method of fat component of formula food for special medical purpose for inflammatory bowel disease
  • Formula and preparation method of fat component of formula food for special medical purpose for inflammatory bowel disease
  • Formula and preparation method of fat component of formula food for special medical purpose for inflammatory bowel disease

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Experimental program
Comparison scheme
Effect test

Embodiment 3

[0064] Embodiment 3 (comparative example):

[0065] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0066] Medium-chain triglycerides: 70%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0067] Nutritional oils: 5.5% linseed oil, 4.5% seabuckthorn seed oil, 6.5% olive oil, 3.5% tea seed oil, 5.5% rice bran oil, 4.5% rapeseed oil.

[0068] Preparation method is with specific embodiment 1.

[0069] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0070] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0071] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat ...

Embodiment 4

[0073] Embodiment 4 (comparative example):

[0074] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0075] Medium-chain triglycerides: 40%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0076] Nutritional oils: cottonseed oil 25%, soybean oil 18%, sunflower oil 17%.

[0077] Preparation method is with specific embodiment 1.

[0078] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0079] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0080] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat components are as follows: figure 2 .

[0081] The HE stainin...

Embodiment 5

[0082] Embodiment 5 (comparative example):

[0083] Fat formula food that can be used for special medical purposes for patients with inflammatory bowel disease, each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0084] Medium-chain triglycerides: 40%, of which, tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1;

[0085] Nutritional oils: peony seed oil 22%, rice bran oil 15%, corn oil 23%.

[0086] Preparation method is with specific embodiment 1.

[0087] The fatty acid composition and oil companions of the obtained fat components were detected and analyzed, as shown in Table 1 and Table 2.

[0088] Nitric oxide secretion levels were compared for the resulting adipose fractions such as figure 1 .

[0089] The results of semi-quantitative PCR of RAW264.7 inflammation-related genes TNF-α and IL-6 carried out on the obtained fat components are as follows: figure 2 .

[0090] The HE staining l...

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Abstract

The invention discloses a fat formula food which can be used for special medical purposes of patients with inflammatory bowel disease and a preparation method thereof. The fat component of the present invention comprises the following raw materials by weight: 40% medium chain triglycerides (tricaprylic acid glyceride: tricapric glycerin mass ratio is 3:1) and by 13% peony seed oil, 14% camellia seed Oil, 9% corn oil, 13% rice bran oil and 11% rapeseed oil. The product of the invention has balanced nutritional components, reasonable fatty acid composition, contains MCT lipids required by patients with inflammatory bowel disease, and is rich in anti-inflammatory active ingredients such as polyphenols, phytosterols and oryzanol, which are easily digested and absorbed by the human body, and are effective for patients with inflammatory bowel disease. Has significant palliative and preventive effects.

Description

technical field [0001] The invention belongs to the technical field of formula food for special medical use, and in particular relates to a fat component formula and preparation method of formula food for special medical purpose for inflammatory bowel disease. Background technique [0002] Inflammatory bowel disease (IBD) is a chronic inflammation of the intestinal tract caused by various etiologies and mediated by abnormal immunity. ,) and ulcerative colitis (Ulcerative Colitis, UC). [0003] Malnutrition is the most common systemic manifestation in IBD patients and may occur at any stage of inflammatory bowel disease. At present, drugs such as aminosalicylic acid, glucocorticoids, and immunosuppressants are the main treatment measures for this disease, but in some cases, the efficacy of drugs is not good, and adverse drug reactions are prone to occur. Studies have shown that in the early and mid-term treatment of patients with inflammatory bowel disease, targeted nutriti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23D9/007A23D9/00
CPCA23D9/007A23D9/00
Inventor 刘睿杰郭怡雯常明张涛裘芳成金青哲王兴国
Owner JIANGNAN UNIV
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