13results about How to "Quick relief" patented technology

The invention provides a battery box quick release device capable of being remotely controlled, which comprises a battery box, an upper bracket, a lower bracket, a locking mechanism, an executing mechanism and an air cylinder, the battery box is fixedly assembled on the upper bracket, the lower bracket is fixed on a vehicle carrier, and the upper bracket and the lower bracket are transversely and slidably connected through a sliding assembly; the locking mechanism is arranged on the lower bracket, the executing mechanism is arranged on the upper bracket, when the upper bracket transversely slides into the lower bracket, the locking mechanism can lock the executing mechanism, and the air cylinder is arranged on the lower bracket. When a vehicle battery box breaks out of fire and other faults occur, the function that a driver controls the air cylinder to be quickly released through a control system in a one-key mode can be achieved, and serious accidents are avoided. When a control system and an air cylinder fail, the quick release function can still be achieved by manually pulling the unlocking body. The sliding assemblies and the idler wheels arranged on the upper bracket and the lower bracket greatly reduce force needed in the releasing process, and therefore it is guaranteed that the releasing action is completed smoothly.

The invention relates to the field of submarine cable equipment, and provides a dynamic submarine cable joint release / installation system which comprises a dynamic submarine cable joint, a connecting base, a bayonet lock, a driving mechanism, a fixing cylinder and a self-locking mechanism arranged on the fixing cylinder, the dynamic submarine cable joint is slidably provided with a locking block and a sliding block, the locking block is inserted into the connecting base, one end of the bayonet lock abuts against the locking block, and the sliding block is inserted into the locking block. The other end penetrates out of the connecting seat; the driving mechanism is connected with the self-locking mechanism, and the connecting seat is provided with a locking groove; when the dynamic submarine cable connector is in a releasing state, the sliding block is retracted in the dynamic submarine cable connector, the connecting base is locked in the fixing cylinder through the self-locking mechanism, and the clamping pin pushes the locking block to be separated from the connecting base under the collision of the fixing cylinder. When the dynamic submarine cable connector is in an installation state, the sliding block extends out of the dynamic submarine cable connector and is inserted into the locking groove, the driving mechanism drives the self-locking mechanism to overturn outwards relative to the fixing cylinder so as to release the connecting base, and therefore rapid releasing and assembling of the dynamic submarine cable connector are achieved, manual underwater operation is not needed, and potential safety hazards are avoided.

The invention belongs to the field of pharmaceutical preparations, and particularly relates to an oral nano-drug delivery system for treating ulcerative colitis. The rosmarinic acid chondroitin sulfate A nanoparticles (RA-CSA nanoparticles) provided by the invention can effectively prevent the adsorption of plasma proteins and improve the stability of the nanoparticles in blood. In a hemolysis test, the RA-CSA nanoparticles have good biocompatibility in blood. A drug release mode of the RA-CSA nanoparticles shows explosive release within 24 hours at first and then enters a stable slow release stage, and the dynamic release mode is beneficial to long-term sustained release of the drug to an inflammatory site, ensures that the drug stays for a longer time in a body, stays for a longer time in a colon and acts for a longer time, and achieves a better anti-inflammatory effect. Meanwhile, the RA-CSA nanoparticles can effectively remove ROS (reactive oxygen species) and have strong antioxidant activity. In addition, compared with free RA, the RA-CSA nanoparticles have the advantages that inflammation activation of macrophages is remarkably reduced, colitis is effectively promoted to be relieved, and the RA-CSA nanoparticles have no obvious in-vivo toxicity.

The invention relates to the technical field of pipeline joints, and discloses a high-sealing-performance insulating joint which comprises a connector, a sleeve cylinder, insulating filler and a U-shaped sealing ring, the sleeve cylinder is connected to the outer side of the connector in a sleeving mode, the space between the connector and the sleeve cylinder is filled with the insulating filler, the U-shaped sealing ring is arranged in the connector, a sealing stabilizing assembly is arranged in the connector, and the U-shaped sealing ring is connected with the U-shaped sealing ring in a sleeving mode. The sealing stabilizing assembly comprises an insulating plate which is arranged in the connector. A buffer is installed for a sealing system by sensing the internal pressure of a pipeline and dynamically adjusting the pressing state of the buffer plate set, initial sealing force is provided, meanwhile, the risk that a sealing piece is damaged due to pressure pulsation is reduced, and the sealing reliability of a connector under the complex working condition is fundamentally improved; through the negative pressure detection mechanism, operation and maintenance personnel can find faults in time and arrange maintenance in a planned mode, and economic losses and safety risks caused by leakage accidents and unplanned shutdown are avoided.

The invention discloses a snare device that can be quickly released, comprising a handle, a guide wire, an unlocking piece and an outer sleeve; wherein the guide wire comprises a fixed end, a free end and a shaping section, the fixed end is fixed to the handle, the shaping section can be pre-shaped into a desired shape before surgery and can be straightened when subjected to a tensile force; the unlocking piece can be movably connected to the handle and has a locked state and an unlocked state, the free end is locked to the handle by the unlocking piece under the snare state, and the shaping section is in a ring shape; in the unlocked state, the unlocking piece releases the free end, the handle is subjected to an outward pulling force to drive the free end to separate from the handle, under the action of the pulling force, the shaping section and the free end are pulled into a straight line with the fixed end, and the guide wire is switched to a linear guide wire state. The snare guide wire can be quickly transformed from the snare state to the guide wire state in the blood vessel, which is convenient for rapid withdrawal of the snare guide wire during surgery.

The invention provides a preparation method of nano-particles capable of regulating the crowding degree in cells, which comprises the following steps: firstly preparing degradable silicon dioxide nano-particles BSN (at) Ficoll containing disulfide bonds entrapped with polysucrose, then modifying amino at the tail end to obtain BSN (at) Ficol-NH2 nano-particles, and then modifying with folic acid and hyaluronic acid to obtain FA-HA-BSN (at) Ficoll nano-particles, namely FHS (at) Ficoll for short. According to the FHS-Ficoll nano-particle disclosed by the invention, the polysucrose is used as a crowding agent, the silicon dioxide is used as a core skeleton, the disulfide bond is used as a polysucrose responsive release switch, and the folic acid and the hyaluronic acid are jointly used as targeting ligands, so that accurate targeted delivery of proinflammatory macrophages and glutathione responsive release crowding agents can be realized, and the crowding degree in cells can be dynamically regulated; and protein is induced to generate phase separation, so that the relieving of inflammatory response can be effectively promoted, and the repair and regeneration process of damaged tissues is accelerated.

This invention belongs to the field of biomedicine and relates to a method for inducing fibroblasts to exhibit an immunosuppressive phenotype. Specifically, this invention relates to a method for inducing fibroblasts to exhibit an immunosuppressive phenotype, comprising the following steps: treating fibroblasts with (1) IFN-γ or (2) IFN-γ and rapamycin. This invention also relates to cell membrane vesicle nanoparticles and their uses. The cell membrane vesicles or cell membrane-encapsulated nanoparticles of this invention can effectively treat or prevent arthritis, especially rheumatoid arthritis, and have good application prospects.

The present invention belongs to the technical field of liquid crystal display materials, and particularly relates to a liquid crystal alignment agent and a method for preparing a high-hardness polyimide liquid crystal alignment film using the same. The liquid crystal alignment agent is composed of the following A component, B component and organic solvent: A component: polyamic acid polymerized from 1,3-bis(4-aminophenylethyl)urea, 4,4'-diaminodiphenylamine and tetracarboxylic dianhydride; B component: polyamic acid polymerized from diamines containing carboxyl and / or hydroxyl groups, p-phenylenediamine, 1,3,5-benzenetricarboxyl chloride and tetracarboxylic dianhydride; The present invention introduces a cross-linking agent having three reactive substituents into a linear polyamic acid chain, and when it is block-polymerized with an imide repeating unit having at least one carboxyl or hydroxyl group during the reaction, a polyamic acid block copolymer having a large molecular weight and cross-linking properties is formed, and the hardness of the formed liquid crystal alignment film is increased by increasing the degree of cross-linking.

The invention discloses a traditional Chinese medicine composition for relieving cough and a preparation method thereof. The composition is prepared from ephedra, almond, gypsum, perillaseed, thunberg fritillary bulb, white mulberry root-bark, cicada slough, radix stemonae, inula flower, clam shell, cynanchum glaucescens, tussilago farfara, schisandra chinensis, loquat leaf, perilla stem, tetrapanax papyriferus, indigo naturalis, semen raphani and liquorice according to a specific ratio. Aiming at the current situation that an existing cough-relieving traditional Chinese medicine prescription is insufficient in consideration of complex syndrome type cough and limited in curative effect, a synergistic compound is formed through combination of multiple methods such as lung freeing, heat clearing, phlegm reducing, qi depressing, spasmolysis and lung astringing, and the traditional Chinese medicine prescription is especially suitable for cough with phlegm-heat stagnating lung, lung dysfunction and descending and airway spasm syndrome.

The invention belongs to the technical field of liquid crystal display materials, and particularly relates to a liquid crystal orientation agent and a method for preparing a high-hardness polyimide liquid crystal orientation film by adopting the same. The liquid crystal aligning agent is composed of a component A, a component B and an organic solvent, wherein the component A is polyamide acid formed by polymerizing 1, 3-bis (4-aminophenylethyl) urea, 4, 4 '-diaminodiphenylamine and tetracarboxylic dianhydride, and the component B is polyamide acid formed by polymerizing 1, 3-bis (4-aminophenylethyl) urea, 4, 4'-diaminodiphenylamine and tetracarboxylic dianhydride; the component B is polyamide acid formed by polymerizing diamine containing carboxyl and / or hydroxyl, p-phenylenediamine, 1, 3, 5-benzoyl chloride and tetracarboxylic dianhydride; according to the invention, a cross-linking agent with three reactive substituent groups is introduced into a polyamide acid chain with a linear structure, and when the cross-linking agent is subjected to block polymerization with an imide repeating unit with at least one carboxyl group or hydroxyl group in the reaction process, a polyamide acid block copolymer with large molecular weight and cross-linking property is formed; the hardness of the formed liquid crystal alignment film is improved by improving the crosslinking degree.

The tactical vest comprises a vest body and shoulder parts, the vest body comprises a front part and a rear part, the two ends of each shoulder part are connected with the front part and the rear part respectively, the front part comprises a first loading layer, the first loading layer is a flame-retardant material component, the first loading layer is arranged on the outermost side of the front part, and the shoulder parts are arranged on the outer side of the first loading layer. Side edge parts are arranged on the two sides of the vest body respectively, each side edge part comprises a magnetic attraction connecting device, one end of each side edge part is connected with the corresponding rear part, and the other end of each side edge part is connected with the corresponding front part through the corresponding magnetic attraction connecting device. Furthermore, magnetic attraction connecting devices are arranged on the two sides of the vest body respectively, so that the vest can be quickly worn and released through the magnetic attraction connecting devices, the requirements of front-line on-duty personnel can be met, and the vest belongs to the field of combat vests.

The invention discloses a quick-release lock which comprises a lock plate, a lock body and a lock sleeve, the lock sleeve is arranged outside the lock body in a sleeving mode, an elastic lock pin assembly is arranged at the upper end of the lock body, a push block return assembly is arranged in the lock body and arranged below the elastic lock pin assembly, a retractable inserting hole is formed in the elastic lock pin assembly, and a lock pin safety buckle is arranged on one side of the retractable inserting hole. The lock body is provided with a sliding block capable of moving up and down, the sliding block is connected with the lock sleeve, a second spring is connected between the sliding block or the lock sleeve and the lock body, the lock plate is used for being inserted into a retractable inserting hole of the elastic lock pin assembly and pushing the push block return assembly into the lock body, and the elastic lock pin assembly retracts through the retractable inserting hole to lock the lock plate. The sliding block is used for moving upwards to be inserted into the lock pin safety buckle of the elastic lock pin assembly, and the retractable insertion hole is prevented from expanding and returning. According to the quick-release lock, one-step connection with one hand and two-step release with one hand can be achieved, and the work efficiency and safety of the quick-release lock are improved.

The present application relates to a kind of typhoon can be released with platform's water isolation sleeve support system and its use method, wherein, typhoon can be released with platform's water isolation sleeve support system for supporting the water isolation sleeve of subsea well, subsea well is configured with deepwater self-elevating production platform around, the deepwater self-elevating production platform includes hull, the water isolation sleeve support system includes moving mechanism, bottom foundation and water isolation sleeve support frame, moving mechanism is set on the deck of hull;Bottom foundation is set to the sea bottom near deepwater self-elevating production platform;The bottom end of water isolation sleeve support frame is detachably connected on the bottom foundation, and the top end of water isolation sleeve support frame is connected with hull by moving mechanism.When typhoon is encountered, the moving mechanism releases water isolation sleeve support frame, realizes that water isolation sleeve support frame is quickly released from deepwater self-elevating production platform when typhoon is encountered;When deepwater self-elevating production platform moves or reinstallation, the moving mechanism will water isolation sleeve support frame be lifted to the deck of hull, realize that deepwater self-elevating production platform is moved together with water isolation sleeve support frame and reinstallation.