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Flos daturae antiasthma powder broken-wall ultramicro powder and preparation process thereof

A preparation process and anti-asthmatic technology, which are applied in the field of Jinhua Pingchuan powder and its cyclically crushed biological fermentation ball mill and wall-breaking preparation technology field, can solve the problems affecting the application effect and treatment range of Jinhua Pingchuan powder, and the low dissolution and release efficiency of active ingredients, etc. problems, to achieve the effect of expanding the application effect, improving the release rate, and achieving a significant effect

Pending Publication Date: 2019-07-26
SHIJIAZHUANG WEIERLI ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Chinese herbal medicine also has many defects, especially in the dosage form, such as insoluble in water, poor absorption and utilization, etc.
[0003] Jinhua Pingchuan Powder is currently used in livestock to relieve asthma and relieve cough. Its raw materials include Yangjinhua, Ephedra, bitter almond, gypsum, and alum. It is generally made into powder after coarse crushing. Its safety and effectiveness have been verified. It is applied to Poultry breeding industry has high feasibility; however, there are shortcomings such as coarse dosage form, low dissolution and release efficiency of active ingredients, which seriously affect the application effect and treatment range of Jinhua Pingchuan Powder

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1, Jinhua Pingchuan powder broken solid superfine powder.

[0025] The Jinhua Pingchuan powder broken wall solid superfine powder of this embodiment, the superfine powder contains the three groups of raw materials of dajinhua, ephedra, and bitter almond whose cell walls have been fully broken, and gypsum and alum auxiliary materials, and dajinhua, ephedra, and bitter almond The ratio of parts by weight of gypsum and alum is 9:4:6:15:5; it is mainly used for relieving asthma and relieving cough of poultry and livestock.

Embodiment 2

[0026] Example 2, Jinhua Pingchuan Powder Broken Wall Dry Suspension Preparation.

[0027] Add poloxamer, mannitol, sucralose, and taste-masking agent to the ultrafine powder in Example 1, and mix thoroughly to obtain a dry suspension powder, which is used for relieving asthma and relieving cough in poultry and livestock.

Embodiment 3

[0028] Example 3, the circulation pulverization process of Jinhua Pingchuan Powder.

[0029] Circular crushing process: Three groups of Chinese medicinal materials are prepared and dried and sent to the pulverizer. A blower is installed at the feed port of the pulverizer, and the Chinese medicinal materials are blown to the crushing part of the pulverizer through the air flow, and a mesh screen is set at the discharge port of the pulverizer. , set the return fan on the outside of the mesh screen, the return fan is intermittently turned on every 1 min, and its blast pressure is 30% higher than that of the supply fan, and the return fan is turned off again for 15 seconds after each startup, and the cycle is repeated; After the raw materials are sent into the pulverizer, they are circulated and pulverized by the action of the return fan until they pass through a 200-300 mesh sieve to obtain Chinese medicinal material powder.

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PUM

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Abstract

The invention discloses flos daturae antiasthma powder broken-wall ultramicro powder and a preparation process thereof. The golden flower antiasthma powder broken-wall ultramicro powder comprises three groups of raw materials of flos daturae, ephedra and bitter almond subjected to full cell wall breaking treatment and auxiliary materials of gypsum and alum in the ratio of (6-12): (2-6): (3-9): (10-20): (3-8). The process develops a new dosage form of flos daturae antiasthma powder for poultry and livestock through the high-efficiency solid dispersion technology, and improves the application range and the application effect of the flos daturae antiasthma powder in the poultry breeding industry.

Description

technical field [0001] The invention relates to the technical field of poultry and livestock breeding, in particular to Jinhua Pingchuan Powder for relieving asthma and relieving cough of poultry and livestock and a preparation process for circulating pulverization, biofermentation, ball milling and wall breaking. Background technique [0002] At present, in the poultry and livestock breeding industry, the use of Chinese herbal medicines has become increasingly widespread. Compared with antibiotics, chemical synthetic drugs and hormone drugs, traditional Chinese medicine has its specific advantages. However, Chinese herbal medicine also has many defects, especially in dosage forms, such as insoluble in water, poor absorption and utilization, etc. [0003] Jinhua Pingchuan Powder is currently used in livestock to relieve asthma and relieve cough. Its raw materials include Yangjinhua, Ephedra, bitter almond, gypsum, and alum. It is generally made into powder after coarse crus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61K9/14A61P11/06A61P11/14A61K33/06
CPCA61K36/81A61K36/17A61K36/736A61K33/06A61K9/146A61P11/06A61P11/14A61K2236/15A61K2236/19A61K2300/00
Inventor 陆安郭宽李磊李华声李娜周斌郭永国
Owner SHIJIAZHUANG WEIERLI ANIMAL PHARMA
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