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Schizonepeta and radix saposhnikoviae toxin-vanquishing powder broken ultra-fine powder for livestock and poultry and preparation process thereof

A preparation technology of Jingfang Baidu powder, which is applied in the field of poultry and livestock breeding, can solve the problems affecting the application effect and treatment range of Jingfang Baidu powder, low dissolution and release efficiency of active ingredients, poor absorption and utilization, etc. To achieve the effect of expanding application effect, improving bioavailability and increasing release rate

Pending Publication Date: 2019-07-09
SHIJIAZHUANG WEIERLI ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Chinese herbal medicine also has many defects, especially in the dosage form, such as insoluble in water, poor absorption and utilization, etc.
[0003] Jingfangbaidu Powder is currently used in the prevention and treatment of viral infections in poultry and livestock. Its raw materials include Nepeta, Fangfeng, Notopterygium, Duhuo, Bupleurum, Peucedanum, Citrus aurantium, Poria, Platycodon grandiflorum, Chuan Shao, licorice, mint, Generally, it is made into powder after coarse crushing, its safety and effectiveness have been verified, and it is highly feasible to apply it to the poultry breeding industry; however, there are shortcomings such as coarse dosage form, low dissolution and release efficiency of active ingredients, which seriously affect the Application effect and scope of application of Jingfangbaidu powder

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1, Jingfangbaidu powder broken solid superfine powder.

[0023] The broken wall solid ultrafine powder of Jingfangbaidu powder in this example, the ultrafine powder contains Nepeta, Fangfeng, Qianghuo, Duhuo, Bupleurum, Peucedanum, Citrus aurantium, Poria cocos, Platycodon grandiflorum, Chuan Shao, whose cell walls have been fully broken. , licorice, and peppermint raw materials; specifically, calculated in parts by weight, it includes: Nepeta 20 parts, Fangfeng 10 parts, Notopterygium 10 parts, Duhuo 10 parts, Bupleurum 12 parts, Peucedanum 8 parts, Citrus aurantium 10 parts, Poria cocos 18 parts, bellflower 12 parts, Chuan Shao 10 parts, licorice 6 parts, mint 5 parts; mainly used for the prevention and treatment of poultry virus infection.

Embodiment 2

[0024] Example 2, Jingfangbaidu powder broken wall dry suspension preparation.

[0025] Add poloxamer, microcrystalline cellulose, glucose, and taste-masking agent to the ultrafine powder in Example 1, mix thoroughly, add a dissolution regulator, and then granulate through a fluidized bed to obtain a dry suspension granule preparation ; Mainly used for the prevention and control of poultry virus infection.

Embodiment 3

[0026] Embodiment 3, the circular crushing process of Jingfangbaidu powder.

[0027] Circular crushing process: Twelve groups of Chinese medicinal materials are prepared and dried and then sent to the pulverizer. A blower is installed at the feed port of the pulverizer, and the Chinese medicinal materials are blown to the crushing part of the pulverizer through air flow, and a net is set at the discharge port of the pulverizer. sieve, a return fan is set outside the mesh screen, the blast pressure of the return fan is 40% higher than that of the supply fan, the return fan is intermittently turned on every 1min, and it is closed again for 8s after each startup, and the cycle is repeated; After the raw materials are sent into the pulverizer, they are circulated and pulverized by the return fan until they pass through a 300-mesh sieve to obtain powdered Chinese herbal medicines.

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PUM

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Abstract

The invention discloses a schizonepeta and radix saposhnikoviae toxin-vanquishing powder broken ultra-fine powder for livestock and poultry The schizonepeta and radix saposhnikoviae toxin-vanquishingpowder broken ultra-fine powder comprises the raw material drugs of schizonepeta, radix saposhnikoviae, notopterygium roots, radix angelicae pubescentis, radix bupleuri, radix peucedani, fructus aurantii, poria cocos, radix platycodonis, radix paeoniae alba, liquorice and mints of which the cell walls are sufficiently broken; the raw material drugs are firstly subjected to cyclic grinding and fermentation and then subjected to cell wall treatment to obtain the schizonepeta and radix saposhnikoviae toxin-vanquishing powder broken ultra-fine powder for the livestock and poultry. The novel dosageform of the schizonepeta and radix saposhnikoviae toxin-vanquishing powder broken ultra-fine powder for the livestock and poultry is developed through an efficient solid dispersion technology, and the range of application and application effect of schizonepeta and radix saposhnikoviae toxin-vanquishing powder in the livestock breeding industry are improved.

Description

technical field [0001] The invention relates to the technical field of poultry and livestock breeding, in particular to a heat-clearing, detoxifying and anti-virus Chinese herbal medicine for poultry and livestock and a preparation process for circulating pulverization, biological fermentation, ball milling and wall breaking. Background technique [0002] At present, in the poultry and livestock breeding industry, the use of Chinese herbal medicines has become increasingly widespread. Compared with antibiotics, chemical synthetic drugs and hormone drugs, traditional Chinese medicine has its specific advantages. However, Chinese herbal medicine also has many defects, especially in dosage forms, such as insoluble in water, poor absorption and utilization, etc. [0003] Jingfangbaidu Powder is currently used in the prevention and treatment of viral infections in poultry and livestock. Its raw materials include Nepeta, Fangfeng, Notopterygium, Duhuo, Bupleurum, Peucedanum, Citr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K9/16A61K36/752A61P31/12B02C21/00B02C23/08B02C17/10
CPCA61K9/14A61K9/1652A61K9/1641A61K9/1623A61K36/538A61K36/238A61K36/237A61K36/232A61K36/233A61K36/23A61K36/752A61K36/076A61K36/346A61K36/71A61K36/65A61K36/484A61K36/534A61P31/12B02C21/00B02C23/08B02C17/10A61K2236/19A61K2236/15
Inventor 陆安李红梅张艳茹李岩程栋刘志杰郭永红
Owner SHIJIAZHUANG WEIERLI ANIMAL PHARMA
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