Maca compositions and methods of use
A composition, the technology of black maca, which is applied in the direction of drug combination, active ingredient of hydroxyl compound, application, etc., can solve problems such as side effects, seriousness, and undesirability
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Embodiment 1
[0181] Example 1: Effects of Maca Compositions under Inflammatory Conditions
[0182] Human peripheral blood mononuclear cell (PBMC) cultures were treated with highly inflammatory bacterial lipopolysaccharide (LPS) from Escherichia coli (positive control). Cultures were incubated for 24 hours before cells and culture supernatants were harvested and used to monitor the response in each culture. Using Luminex magnetic bead arrays and For multiplex system testing of selected cytokines, supernatants from each culture were used to test a panel of pro- and anti-inflammatory cytokines and antiviral chemokines such as Figure 1-11 shown.
[0183] Cell activation assays were performed such that all treatments, including each dose of test product and each positive and negative control, were tested in triplicate. Tests for cytokine production were tested in duplicate. The test is performed on cells from a healthy blood donor.
[0184] The mean and standard deviation of each data ...
Embodiment 2
[0198] Example 2: Effect of Maca Composition on Inflammation
[0199] A double-blind, randomized, parallel-group dose-finding pilot study in 40 outpatients (average age 30 years; half female, half male) with a daily regimen of appropriate doses of maca composition versus placebo Compare. These patients have a diagnosed chronic inflammatory and / or autoimmune disease, disorder or condition. The composition may eg comprise a predetermined amount of Maca per kilogram of body weight of the subject. Subjects are required to have exhibited symptoms of a chronic inflammatory and / or autoimmune disease, disorder or condition at least six months prior to starting the trial and may not have started any new drug therapy within six months of starting the trial.
[0200] The subjects were divided into 8 groups, Group A, Group B, Group C, Group D and Group E. Group A was the control group, group B received yellow maca only, group C received 1:1 black to red maca, group D received 4:1 bla...
Embodiment 3
[0202] Example 3: Effects of Maca Compositions on Libido and Sexual Function
[0203] A double-blind, randomized, parallel-group dose-finding pilot study was conducted to compare a daily regimen of maca composition at an appropriate daily dose (vs. placebo control), the patient was diagnosed with sexual dysfunction. The composition may eg comprise a predetermined amount of Maca per kilogram of body weight of the subject. Subjects must meet one of the following criteria for at least 4 weeks: (1) inability to achieve orgasm during sexual activity (anorgasm); Time to orgasm was meaningfully delayed and interfered with sexual function; (3) inability to achieve or maintain adequate erectile or lubricated protuberant responses to sexual arousal prior to completion of sexual activity according to self-report, i.e. comparable to pretreatment with antidepressants (4) decreased libido according to self-report.
[0204] Exclusion criteria included: primary or prior diagnosis of sexu...
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