Generalized predictive control closed-loop insulin infusion system based on adaptive reference curve strategy

A generalized predictive control and reference curve technology, applied in the direction of adaptive control, general control system, control/regulation system, etc., can solve problems such as difficult to achieve control effect

Inactive Publication Date: 2019-08-16
GUANGDONG FOOD & DRUG VOCATIONAL COLLEGE +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its disadvantage is that the selection and construction of the model is often based on the physiological model of the patient's glucose metabolism, and the parameters need to be set with refer...

Method used

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  • Generalized predictive control closed-loop insulin infusion system based on adaptive reference curve strategy
  • Generalized predictive control closed-loop insulin infusion system based on adaptive reference curve strategy
  • Generalized predictive control closed-loop insulin infusion system based on adaptive reference curve strategy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0112] Such as figure 1 and figure 2 As shown, a generalized predictive control closed-loop insulin infusion system based on an adaptive reference curve strategy, including a blood glucose detection module, a controller, an insulin pump, a TF card and a program module, wherein,

[0113] The chip model of the controller is ARM920T chip;

[0114] The blood sugar level detection module is used to collect the user's blood sugar level, and the output end of the blood sugar level detection module is connected to the input end signal of the ARM920T chip;

[0115] The insulin pump is used to infuse insulin to the user, and the input terminal of the insulin pump is connected to the output terminal of the ARM920T chip;

[0116] The program module is stored in the TF card and executed by the ARM920T chip, including the following steps:

[0117] S1: Collect the current blood glucose level of the user through the blood glucose level detection module;

[0118] S2: According to the bloo...

Embodiment 2

[0155] Such as figure 1 and figure 2 As shown, a generalized predictive control closed-loop insulin infusion system based on an adaptive reference curve strategy, including a blood glucose detection module, a controller, an insulin pump, a TF card and a program module, wherein,

[0156] The chip model of the controller is ARM920T chip;

[0157] The blood sugar level detection module is used to collect the user's blood sugar level, and the output end of the blood sugar level detection module is connected to the input end signal of the ARM920T chip;

[0158] The insulin pump is used to infuse insulin to the user, and the input terminal of the insulin pump is connected to the output terminal of the ARM920T chip;

[0159] The program module is stored in the TF card and executed by the ARM920T chip, including the following steps:

[0160] S1: Collect the current blood glucose level of the user through the blood glucose level detection module;

[0161] S2: According to the bloo...

Embodiment 3

[0198] Such as figure 1 and figure 2 As shown, a generalized predictive control closed-loop insulin infusion system based on an adaptive reference curve strategy, including a blood glucose detection module, a controller, an insulin pump, a TF card and a program module, wherein,

[0199] The chip model of the controller is ARM920T chip;

[0200] The blood sugar level detection module is used to collect the user's blood sugar level, and the output end of the blood sugar level detection module is connected to the input end signal of the ARM920T chip;

[0201] The insulin pump is used to infuse insulin to the user, and the input terminal of the insulin pump is connected to the output terminal of the ARM920T chip;

[0202] The program module is stored in the TF card and executed by the ARM920T chip, including the following steps:

[0203] S1: Collect the current blood glucose level of the user through the blood glucose level detection module;

[0204] S2: According to the bloo...

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Abstract

The invention discloses a generalized predictive control closed-loop insulin infusion system based on an adaptive reference curve strategy. The system comprises a blood glucose detection module, a controller, a program module and an insulin pump, the blood glucose detection module is used for acquiring the blood glucose of a user, and an output end of the blood glucose detection module is connected with an input end of the controller through signals. The insulin pump is used for infusing insulin into the user, and an input end of the insulin pump is connected with an output end of the controller through signals. The program module is executed by the controller, acquires the blood glucose of the user through the blood glucose detection module and adjusts the infusion rate of the insulin pump according to a CARIMA (controlled autoregressive integral moving average) model, a minimum variance control algorithm and the adaptive reference curve strategy. According to the generalized predictive control closed-loop insulin infusion system based on the adaptive reference curve strategy, adaptive reference curves can be generated according to blood glucose fluctuation of different patients,so that the infusion rate of the insulin pump can be flexibly controlled.

Description

technical field [0001] The invention relates to the field of insulin pump infusion, and more specifically, to a generalized predictive control closed-loop insulin infusion system based on an adaptive reference curve strategy. Background technique [0002] The existing control algorithms of insulin infusion devices include proportional calculus control algorithms, fuzzy control algorithms, model control algorithms and so on. [0003] Proportional Integral Derivative (PID) control is a relatively mature and widely used industrial control algorithm. The design of the insulin pump based on the PID algorithm has been realized by the Steil team of Medtronic MiniMed. Its main design idea is: the three components of the PID algorithm, the proportional, differential and integral components, respectively simulate the physiological transmission process of insulin secreted by human β cells. Among them, the linear proportional component corresponds to the insulin secretion when the meas...

Claims

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Application Information

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IPC IPC(8): A61M5/142A61M5/168G05B13/04
CPCA61M5/142A61M5/16804A61M5/16877A61M2005/14208A61M2005/14292A61M2205/3331A61M2205/3553A61M2230/201G05B13/042G05B13/048A61M2230/005
Inventor 金浩宇刘文平余丽玲陈婷
Owner GUANGDONG FOOD & DRUG VOCATIONAL COLLEGE
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