Embryo time difference cultivation device

Abstract

The invention discloses an embryo time difference cultivation device comprising at least one independent time difference cultivation module for culturing samples, wherein the time difference cultivation module comprises a cultivation module and a microscopic imaging system. The microscopic imaging system comprises a light source and a correspondingly matched imaging device. The light source is located at the upper part of the cultivation module, and can move independently in the horizontal axis direction. The imaging device is located at the lower part of the cultivation module, can move independently in the horizontal axis direction parallel to the movement trajectory of the light source, also can move independently in the vertical axis direction perpendicular to the movement trajectory of the light source. Embryos are in independent cultivation spaces, the cultivation environments are independent with each other, and the fetching and placing of the embryos do not interfere with eachother; the embryos do not need to move in the cultivation process and normal development is not interfered; each embryo is photographed independently, and the cumulative exposure time is less.

Description

technical field [0001] The invention relates to the technical field of biological sample cultivation, in particular to an embryo jet lag culture device. Background technique [0002] With the full liberalization of the national two-child policy, in vitro fertilization-embryo transfer (IVF-ET), as a human assisted reproductive technology that can treat infertility, has received more attention. However, the low pregnancy rate is one of the bottlenecks in the development of assisted reproductive technology today. How to improve the availability of embryos and obtain a higher clinical pregnancy rate has become a research hotspot in the field of assisted reproductive technology. [0003] In the field of assisted reproduction, in the traditional in vitro fertilized egg selection process, the embryos are generally cultured and developed in a conventional incubator, and the embryos are taken out at a specific time point and observed under a microscope, and the embryos are evaluated ...

AI Technical Summary

Problems solved by technology

Due to the relatively small irradiated area of ​​the fixed light source, in order to ensure that all embryos are within the imaging field of view, the space arrangement of the embryos in the petri dish is very crowded, which makes it more difficult, more careful, and even mistakes for users to perform micro-operations and move the petri dish risk

In addition, when each embryo is photographed, the exposure of the light source will illuminate the entire field of view, and other embryos will receive unnecessary light, resulting in more cumulative exposure time for the embryos.

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