Metal complexes containing [1,2,4]triazolo[4,3-a]pyridine structural units and their applications
A structural unit, 3-a technology, applied to compounds containing elements of group 8/9/10/18 of the periodic table, palladium organic compounds, platinum-based organic compounds, etc., can solve the problems of limited metal-organic small molecules, Achieve the effect of improving the utilization rate of radiant radiation energy, high thermal stability, and suppressing rotation and vibration
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Examples
Embodiment 1
[0076] Example 1: The platinum complex Pt1 can be synthesized as follows:
[0077]
[0078] Synthesis of intermediate 3a: Into a dry three-necked flask with a magnetic stirring rotor and a condenser tube, intermediate 1a (1.76 g, 25.20 mmol, 1.0 equiv.), intermediate 2a (5.13 g, 27.70 mmol, 1.1 equiv.) were sequentially added and then The nitrogen was purged three times, and absolute ethanol (70 mL) was added under nitrogen protection. The mixture was stirred and reacted in an oil bath at 80°C for 24 hours, cooled to room temperature, and the solvent was distilled off under reduced pressure. Then add iodine element (7.66g, 30.24mmol, 1.1eq), potassium carbonate (10.45g, 75.60mmol, 3.0eq), stir in dichloromethane solution (300mL) at room temperature for 24 hours, monitor by thin layer chromatography until the reaction of the raw materials is completed . Part of the solvent was spun off under reduced pressure distillation, the concentrated reaction solution was washed three...
Embodiment 2
[0081] Example 2: The platinum complex Pt2 can be synthesized as follows:
[0082]
[0083] Synthesis of Ligand 2: Into a dry three-necked flask with a magnetic stirring rotor and a condenser tube, add Intermediate 4b (400 mg, 1.51 mmol, 1.0 equiv), Intermediate 3a (501 mg, 1.82 mmol, 1.2 equiv), iodination Cuprous (29 mg, 0.15 mmol, 10 mol %), pyridine 2-carboxylate (37 mg, 0.30 mmol, 20 mol %), potassium phosphate (802 mg, 3.78 mmol, 2.5 equiv) were then purged with nitrogen three times, and DMSO ( 10mL). The mixture was stirred and reacted in an oil bath at 120°C for 24 hours, monitored by thin layer chromatography until the completion of the reaction of the starting materials, and cooled to room temperature. A small amount of brine was added and extracted with ethyl acetate. The organic layer was washed twice with water, and the aqueous layer was extracted twice with ethyl acetate. The organic phases were combined, dried over anhydrous sodium sulfate, and filtered. ...
Embodiment 3
[0085] Embodiment 3. Platinum complex Pt3 can be synthesized according to the following route:
[0086]
[0087] Synthesis of Ligand 3: To a dry three-necked flask with a magnetic stirring rotor and a condenser tube, add Intermediate 3a (812 mg, 2.80 mmol, 1.0 equiv), Intermediate 4c (844 mg, 3.08 mmol, 1.1 equiv), iodine Cuprous (53 mg, 0.28 mmol, 10 mol%), pyridine 2-carboxylate (68 mg, 0.56 mmol, 20 mol%), potassium phosphate (1.49 g, 7.00 mmol, 2.5 equiv), then purged with nitrogen three times, under nitrogen protection DMSO (15 mL) was added at the bottom. The mixture was stirred and reacted in an oil bath at 120°C for 24 hours, monitored by thin layer chromatography until the completion of the reaction of the starting materials, and cooled to room temperature. A small amount of brine was added and extracted with ethyl acetate. The organic layer was washed twice with water, and the aqueous layer was extracted twice with ethyl acetate. The organic phases were combine...
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