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Method for drying and forming kelintong capsule

A technology for Kelintong capsules and a production method, which is applied in the field of drying and molding production of Kelintong capsules, can solve the problems of large labor and material cost, influence on drug quality, and many production processes, and achieves reduction of labor and material resources, guaranteeing drug efficacy and flow. good effect

Inactive Publication Date: 2019-11-08
GUIZHOU LIANSHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims at drying-crushing-wet granulation-drying-crushing-sieving in the existing Kelintong capsule drying molding production process, the whole production process has many production processes and the cost of manpower and material resources is relatively large, and there is a crossover in production. Pollution, the quality of medicines will be affected to a certain extent, and a production method of Kelintong capsules is provided by drying and forming

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A production method of Kelintong capsules by drying and forming, comprising the following production steps:

[0023] S1, raw material ingredients of Kelintong capsules, select appropriate amount of Kelintong capsules extract and cornstarch;

[0024] S2, preheating, adding cornstarch to the bottom material of the fluidized bed granulation chamber, sending compressed air and steam to the raw material container trolley;

[0025] S3, granulating, spraying the heated Kelintong capsule extract onto the base material to obtain Kelintong capsule granules;

[0026] S4, drying, drying the Kelintong capsule granules to obtain shaped Kelintong capsule granules.

[0027] In use, through the combination of spray drying technology and fluidized bed technology, the principle is that hot air enters the fluidized bed granulation chamber from the bottom distribution plate, agitates and suspends the corn starch in the granulation chamber into a fluidized state, and produces Mixing, the a...

Embodiment 2

[0031] A production method of Kelintong capsules by drying and forming, comprising the following production steps:

[0032] S1, raw material ingredients of Kelintong capsules, in parts by weight, select an appropriate amount of Kelintong capsules extract as 2 parts, and cornstarch as 0.5 parts;

[0033] S2, preheating, mixing the pulverized material, microcrystalline cellulose and corn starch to prepare a mixture, and adding the mixture to the bottom material of the fluidized bed granulation chamber, first feeding compressed air, and waiting for the air pressure in the raw material container trolley to rise After reaching 0.4Mpa, preheat for 20 minutes to make the temperature reach 40°C;

[0034] S3, granulation, control the temperature of the compressed air to be 105°C, and after the temperature of the mixture reaches 65°C, spray the heated Kelintong capsule extract onto the base material to obtain Kelintong capsule granules ;

[0035] S4, drying, drying the Kelintong capsu...

Embodiment 3

[0040] A production method of Kelintong capsules by drying and forming, comprising the following production steps:

[0041] S1, raw material ingredients of Kelintong capsules, in parts by weight, select an appropriate amount of Kelintong capsules extract as 5 parts, and cornstarch as 1.5 parts;

[0042] S2, pulverizing, pulverizing ginseng, velvet antler, cordyceps sinensis, Eucommia ulmoides, sealwort, dodder, psoralen decoction pieces, the particle size of the pulverized product is 30 mesh, and the pulverized product is obtained;

[0043] S3, preheating, mixing pulverized material, microcrystalline cellulose and cornstarch to prepare a mixture, and adding the mixture to the bottom material of the fluidized bed granulation chamber, first feeding compressed air, and waiting for the air pressure in the raw material container trolley to rise After reaching 0.6Mpa, preheat for 20 minutes to make the temperature reach 40°C;

[0044] S4, granulation, control the temperature of the...

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Abstract

The invention relates to the technical field of medicine active ingredients, in particular to a method for drying and forming a kelintong capsule. The method for drying and forming the kelintong capsule comprises the steps that appropriate amount of kelintong capsule extract and corn starch are selected, then the heated kelintong capsule extract is sprayed onto base materials to prepare kelintongcapsule particles, finally, the kelintong capsule particles are dried, and formed kelintong capsule particles are obtained. On the basis of method for drying and forming the kelintong capsule, the problems that through drying-crushing-wet granulation-drying-crushing-screening in the prior art of the dry-forming production processes of the kelintong capsule, the production process of the whole production process is relatively more, the cost of manpower and material resources is relatively large, the cross-contamination exists in the production, and the quality of the medicine can be affected are solved.

Description

technical field [0001] The invention relates to the technical field of active ingredients of medicines, in particular to a production method of Kelintong capsules by drying and molding. Background technique [0002] Kelintong Capsules have the effects of clearing away heat and purging fire, diuresis and treating stranguria. It is used for the treatment of hot shower caused by damp heat, hot stagnation in the bladder, frequent urination, urgency, dysuria, lower abdominal pain, low back pain, yellow greasy fur, slippery and rapid pulse and other symptoms. [0003] In the production of granules, the Kelintong capsule extract is prefabricated through Polygonum cephalum and Cortex Phellodendri, and then dried-crushed-wet granulated-dried-crushed-sieved. The entire production process requires a lot of manpower and material resources. The cost is high, and there is cross-contamination in production, and the quality of medicines will be affected to a certain extent. Contents of t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/48A61K47/38A61K47/36A61P13/00A61P29/00A61K35/32
CPCA61K9/1652A61K35/32A61K36/068A61K36/258A61K36/39A61K36/43A61K36/46A61K36/487A61K36/8969A61P13/00A61P29/00A61K2300/00
Inventor 徐会罗玉江周英
Owner GUIZHOU LIANSHENG PHARMA