Application of phellinus igniarius as tumor-treating drug

The technology of a tumor drug and Phellinus linteus is applied in the application field of Phellinus linteus as a drug for treating tumors, which can solve the problems of low survival rate of inoculation, and achieve the effects of improving the survival rate, good curative effect, important economic benefits and social benefits.

Inactive Publication Date: 2019-11-22
浙江千济方医药科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The Phellinus species involved in the patent application number: 201410788390.3 is: Phellinus igniarius (L.e×Fr.) Quel (Porina spp. of Polyporaceae). Phellinus fungus grows on "

Method used

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  • Application of phellinus igniarius as tumor-treating drug
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  • Application of phellinus igniarius as tumor-treating drug

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0341] Embodiment 1: Phellinus granule preparation

[0342] Take Phellinus 2000g, prepare according to the following method:

[0343] (a) Add 15 times the amount of water for the first time, decoct for 2 hours, add 12 times the amount of water for the second time, decoct for 2 hours, combine the medicinal liquid, filter the medicinal liquid, take the filtrate, concentrate to a relative density of 1.10-1.15 (60 ℃), add 95% ethanol to make the alcohol content reach 80%, precipitate, let it stand for 24 hours, filter to obtain a precipitate, and recover the ethanol from the filtrate to obtain a water extract;

[0344] (b) the water extract is concentrated, dried, and pulverized to obtain a dry cream powder;

[0345] (c) the precipitate is dried and pulverized to obtain a precipitated powder;

[0346] (d) Fully mix the obtained dry paste powder and precipitated powder with an appropriate amount of dextrin, granulate with ethanol as a binder, and dry to make granules.

Embodiment 2

[0347] Embodiment 2: Phellinus Phellinus granule preparation

[0348] Take Phellinus 3000g, prepare according to the following method:

[0349] (a) Add 15 times the amount of 95% ethanol to reflux and extract twice, the first time is 3 hours, and the second time is 2 hours. Combine the medicinal liquids, filter the medicinal liquids, recover ethanol, and obtain an alcohol extract;

[0350] (b) Add water to decoct the medicinal dregs after alcohol extraction twice, add 15 times the amount of water for the first time, decoct for 2 hours, add 12 times the amount of water for the second time, decoct for 2 hours, combine the medicinal liquid, and filter the medicinal liquid , take the filtrate, concentrate until the relative density is 1.10-1.15 (60°C), add 95% ethanol to make the alcohol content reach 80%, precipitate, let stand for 24 hours, absorb the supernatant, reclaim the ethanol, and obtain the water extract;

[0351] (c) the resulting alcohol extract and water extract ar...

Embodiment 3

[0353] Embodiment 3: Phellinus Phellinus tablet preparation

[0354] Take Phellinus 25000g, prepare according to the following method:

[0355] (a) Add 15 times the amount of water for the first time, decoct for 2 hours, add 12 times the amount of water for the second time, decoct for 2 hours, combine the medicinal liquid, filter the medicinal liquid, take the filtrate, concentrate to a relative density of 1.10-1.15 (60 ℃), add 95% ethanol to make the alcohol content reach 70%, precipitate, let it stand for 24 hours, absorb the supernatant, reclaim the ethanol, and obtain the water extract;

[0356] (b) concentrating, drying, and pulverizing to obtain dry cream powder;

[0357] (c) the precipitate is dried and pulverized to obtain a precipitated powder;

[0358] (d) Fully mix the obtained dry cream powder and precipitated powder with sucrose, granulate with ethanol liquid as a binder, dry, add an appropriate amount of magnesium stearate and mix evenly, and make tablets.

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Abstract

The invention discloses an application of phellinus igniarius as a tumor-treating drug, and relates to the technical field of drugs. The phellinus igniarius strain and a growth process is characterized in that: firstly, the phellinus igniarius strain is sanghuangporus baumii; secondly, a cultivation step of a substitute material comprises the steps of 1, the cultivation of the substitute materialtakes a technical mode of cultivating phellinus igniarius with wood bits, wheat bran and other mixed raw materials; and 2, a production technological process of a substitute material bacteria stick comprises the steps of material preparation, material mixing, bagging, sterilization, cooling, and inoculation; and thirdly, ingredients of the culture medium comprise mulberry branch wood bits, quercusmongolica fisch (mongolian oak), oak and other wood bits as main materials, and wheat bran and soybean meal as auxiliary materials. The phellinus igniarius is applied as the tumor-treating drug, canimprove the survival rate of the phellinus igniarius, can prove that the phellinus igniarius has good anti-tumor effect, has good curative effect on lung cancer, liver cancer, stomach cancer, colon cancer, cervical cancer, breast cancer, ovarian cancer, leukemia, prostatic cancer, melanoma, neuroblastoma and other tumors, and has important economic benefits and social benefits.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to the application of Phellinus Phellinus as a drug for treating tumors. Background technique [0002] Phellinus species, identified as Hymenochaetales, Hymenochaetaceae, and Sanghuangporus; Chinese name: Sanghuangporus, common name: clove Phellinus, Latin scientific name: Sanghuangporus baumii. Synonyms: Inonotus baumii; Phellinus baumii. [0003] The Phellinus species involved in the patent application number: 201410788390.3 is: Phellinus igniarius (L.e×Fr.) Quel (Porina spp. of Polyporaceae). Phellinus fungus grows on "tree sections of oak trees and other trees", and the trees are directly cut into small sections, Phellinus fungus grows on the tree sections, and the survival rate of inoculation is low. Contents of the invention [0004] The object of the present invention is to aim at the defects and deficiencies of the prior art, and provide Phellinus Phellinus which can i...

Claims

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Application Information

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IPC IPC(8): A61K36/07A61P35/00
CPCA61K36/07A61P35/00
Inventor 李宁
Owner 浙江千济方医药科技有限公司
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