Isoquinoline tricyclic alkaloid compound as well as preparation method and application thereof

A technology of alkaloids and compounds, applied in the fields of botanical equipment and methods, chemicals for biological control, applications, etc., to achieve the effects of large biological yield, high alkaloid content and wide distribution
CN110483535AActive Publication Date: 2019-11-22CHINA TOBACCO YUNNAN IND
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
CHINA TOBACCO YUNNAN IND
Publication Date
2019-11-22

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Abstract

The invention discloses an isoquinoline tricyclic alkaloid compound as well as a preparation method and application thereof. The compound is obtained by taking a whole plant of Thalictrum glandulosissimum as a raw material and by steps of extraction with ethyl acetate, silica gel column chromatography and high-pressure liquid chromatography separation and purification. The structural formula of the compound is C16H15NO2, and the compound has the following structural formula shown in the specification. The compound is named as 1-(2,2-dimethyl-2H-pyrano[2,3-g]isoquinolin-6-yl)ethanone. The inhibitory effect of the compound on Phytophthora nicotianae is remarkably superior to that of agricultural streptomycin, and the control effect on tobacco black shank reaches (71.5 + / - 3.2)%. The raw material is widely distributed, high in biological yield and high in alkaloid content. The compound preparation process is simple, the production cost is low and the compound is prone to industrial application.
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Description

technical field

[0001] The invention belongs to the technical field of biopesticides, and in particular relates to an isoquinoline tricyclic alkaloid compound obtained by extracting and separating for the first time from the horsetail lotus. At the same time, the invention also relates to the preparation method of the compound and the application of the compound in the prevention and treatment of tobacco black shank. Background technique

[0002] Thalictrum L. (Latin scientific name: Thalictrum L.) is a perennial herb of the family Ranunculaceae. There are about 200 species of this genus in the world, which are widely distributed in Asia, Europe, Africa, North America and South America; among them, there are about 67 species in China, which are distributed in all provinces and regions of the country, and most of them are distributed in the southwest. About 29 species of plants in this genus are available for medicinal purposes, and many plants in this genus have the effects...

Claims

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