Application of active peptides from oysters in wound repair

Abstract

The invention provides application of active peptides from oysters in wound repair. The active peptides from oysters have a novel use of repairing skin wounds. A preparation method of the active peptides from oysters comprises the following steps: washing all organs of oysters, and carrying out beating so as to obtain oyster pulp; adjusting the pH value of the oyster pulp to 7.0, and adding animalprotease with an activity of 800-1700 U / g protein, and conducting enzymatic hydrolysis for 3.5-5.5 hours; after completion of the enzymatic hydrolysis, carrying out enzyme inactivation at 100 DEG C for 10 minutes, and carrying out centrifuging at a rate of 8000-12000 r / min so as to obtain liquid supernatant; carrying out full filtration by using a selected ceramic membrane of which the aperture is 0.05-0.5 microns; carrying out separation by using ultra-filtration membranes with various molecular weight cut-offs so as to obtain an enzymatic hydrolyzate of which the molecular weight is smallerthan 3000Da; and then, carrying out concentration, carrying out storing at -80 DEG C for 24 hours, and carrying out freeze-drying so as to obtain the active peptides from oysters. The active peptidesfrom oysters provided by the invention have novel usage in skin trauma medicines, including medicines used for repairing skin burns, wounds, cauma, scalds and the like; and moreover, the use effectsof the skin trauma medicines with the active peptides from oysters are obviously better than the use effects of the medicines in the prior art. Thus, quick wound repair without scar remaining can be achieved, so that, the skin trauma medicines with the active peptides from oysters has more obvious wound repair promotion effects.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to the application of an oyster active peptide in wound repair. Background technique [0002] Hong Kong oyster (Crossostrea sikamea) is the main cultured species in the South my country Sea. It has delicious meat and rich and comprehensive nutrition. It is known as "sea milk". Oysters are the first batch of foods that are selected as food and medicine homologous. The research team and other scholars have found that oyster peptides have functional activities such as anti-oxidation, immunity, anti-fatigue, anti-tumor, antibacterial, memory improvement, hangover and liver protection. It has laid a theoretical foundation for promoting wound healing, but there are no relevant reports on its in-depth medicinal value. Therefore, it is very necessary to fully develop and utilize the research on the functional value of oysters. [0003] Wound healing is a complex process i...

AI Technical Summary

Problems solved by technology

Oysters are the first batch of food selected into the same source of food and medicine. The research team and other scholars have found that oyster peptides have functional activities such as anti-oxidation, immunity, anti-fatigue, anti-tumor, antibacterial, memory improvement, hangover and liver protection. It has laid a theoretical foundation for promoting wound healing, but there are no relevant reports on its in-depth medicinal value, so it is necessary to fully develop and utilize the research on the functional value of oysters

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