Gel tube preparation device and micron-sized gel tube prepared by same and used for glaucoma drainage

Abstract

The invention provides a gel tube preparation device and a micron-sized gel tube prepared by the gel tube preparation device and used for glaucoma drainage, and relates to the technical field of medical new materials. The gel tube preparation device comprises a gel cavity, a metal wire and a wire drawing device; the gel cavity is mainly composed of a gel inner cavity and a heat preservation outercavity which are arranged in an inside-outside wrapping mode. Meanwhile, the gel cavity is provided with a metal wire inlet and a metal wire outlet; the metal wire enters the gel cavity from the metalwire inlet through the wire drawing device, penetrates out of the center of the metal wire outlet after being adhered with gel in the gel inner cavity to obtain a metal wire coated with the gel on the outer layer, and is drawn out after being cured and formed to prepare the gel tube; in addition, the ratio of the inner diameter of the metal wire outlet to the diameter of the metal wire is 4-2: 1.Compared with a hose prepared through an existing solution adsorption solidification method, the micron-sized gel tube for glaucoma drainage and prepared through the preparation device has the advantages of being smooth in surface and uniform in thickness.

Description

technical field [0001] The invention relates to the technical field of new medical materials, in particular to a gel tube preparation device and the prepared micron gel tube for glaucoma drainage. Background technique [0002] Glaucoma is one of the three major blindness diseases of human beings, with an incidence rate of 1% in the total population and 2% after the age of 45. Glaucoma causes abnormal high pressure in the eye, which can lead to damage to the optic nerve. As the patient grows older, the intraocular pressure will continue to increase causing continuous damage to the optic nerve. The current main treatment methods focus on lowering the intraocular pressure, keeping the intraocular pressure within the normal range, and ensuring that the patient can maintain a certain vision. [0003] Traditional treatments include the use of medications to reduce pressure inside the eye. However, drug treatment can cause many adverse reactions and cannot accurately control int...

AI Technical Summary

Problems solved by technology

However, the current glaucoma drainage valve device has a large volume and heavy trauma. It is easy to cause infection after surgery and leave scar tissue. In severe cases, a second surgery may even be required.

In addition to the drainage valve device, the metal drainage nail is also a more commonly used method recently. However, the metal drainage nail is hard and has a strong foreign body sensation, which makes patients feel poor in use.

[0004] In recent years, there have also been some treatment plans that use micron-sized hoses as glaucoma drainage tubes to export aqueous humor into the trabecular meshwork to reduce intraocular pressure. However, the existing micron-sized hoses are all prepared by the method of solution adsorption and coagulation. For example, CN107811752A discloses a scheme in which a tubular formwork is added into a chitosan solution, and then a micron-scale hose is prepared by the method of chitosan adsorption and solidification, but there is an obvious problem in the hoses made by this type of scheme. The surface of the hose is uneven and the thickness is not uniform. At the same time, the preparation process of this kind of scheme is complicated, time-consuming and labor-intensive, and the economy is poor

[0005] Therefore, research and development of a micron-scale gel tube for glaucoma drainage and its preparation device has the advantages of simple preparation process, easy-to-control process, and smooth surface and uniform thickness, so as to ease the pain caused by the soft gel tube prepared by the existing coating coagulation method. The problem of complex pipe preparation process, uneven surface and uneven thickness has become very necessary and urgent

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