A method of manufacturing a focus-adjustable photoacoustic endoscopic microscope
A production method and an endoscope technology, which are applied in the field of photoacoustic endoscopy, can solve the problems of low resolution, large device size, limited image quality, etc., and achieve high resolution, small size, and high resolution. Effect
Active Publication Date: 2021-06-04
SHANGHAI JIAOTONG UNIV
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Problems solved by technology
(i) At present, in the photoacoustic microscopy imaging system, a variety of techniques for increasing the imaging depth of field have been proposed, but limited by the size of the imaging head, they cannot be directly used for endoscopic imaging
(ii) At present, some research groups have demonstrated photoacoustic endoscopes with large depth of field, but their device size is too large, which limits the convenience of clinical use; and the resolution is relatively low, which limits the image quality
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[0031] In order to make the technical means, creative features, goals and effects achieved by the present invention easy to understand, the present invention will be further described below in conjunction with specific embodiments.
[0032] see Figure 1 to Figure 9 A method for manufacturing a focus-adjustable photoacoustic endoscopic microscope according to the present invention includes making an endoscope and increasing the depth of field. The making of the endoscope includes the following steps:
[0033] (1), such as figure 1 As shown in (i), the single-mode optical fiber 1 is fixed among the first plastic pipe 2;
[0034] (2), such as figure 1 As shown in (ii), first insert the first plastic tube 2 into a second plastic tube 3 with a side window. The second plastic pipe comprises two sections of closed pipes and a section of opening about 270° side window, and the position of the side window of the second plastic pipe is the part connecting the two sections of closed ...
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Abstract
The invention discloses a method for manufacturing a focus-adjustable photoacoustic endoscope, which includes the manufacture of the endoscope and the increase of the depth of field. (i) by adjusting the distance between the single-mode optical fiber and the lens, the laser focus can be changed The focus position (that is, change the focal length); then, images of different focal planes can be obtained through one-dimensional or two-dimensional scanning; and then these images can be fused to obtain a photoacoustic image with an increased depth of field, which solves the shortcoming of a small depth of field; (ii) The manufacturing method of the focus-adjustable photoacoustic endoscopic microscope proposed by the present invention has small size and high resolution, which solves the shortcomings of large size and relatively low resolution.
Description
technical field [0001] The invention relates to the field of photoacoustic endoscopic microscopes, in particular to a method for manufacturing a focus-adjustable photoacoustic endoscopic microscope. Background technique [0002] Photoacoustic endoscopic imaging is a technical solution based on the use of a miniature imaging head that can be inserted into the body to obtain images of internal organs. Photoacoustic endoscopic imaging can be further divided into acoustic resolution photoacoustic endoscopic imaging and optical resolution photoacoustic endoscopic imaging. Acoustic resolution, by using focused or unfocused ultrasound transducers, can provide resolutions of tens to hundreds of microns; optical resolution, by using focused laser spots, can achieve resolutions of up to a few microns. Therefore, optical resolution photoacoustic endoscopic imaging is expected to obtain clear images of fine tissues in an endoscopic form, such as capillary imaging. However, a character...
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IPC IPC(8): A61B5/00G02B23/24G02B23/26
CPCA61B5/0033A61B5/0095A61B5/6847A61B5/72G02B23/2438G02B23/26
Inventor 陈松良郭震东叶展鸿
Owner SHANGHAI JIAOTONG UNIV