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Huanglian Shangqing tablets and preparation method thereof

A technology of coptis supernatant tablets and ointment, applied in the field of pharmaceuticals, can solve the problems of many production steps, high production cost, complicated process, etc., achieve the effect of beautiful tablet shape, reduce production steps, and reduce lobes or piebald spots

Inactive Publication Date: 2019-12-13
HUIYINBI GROUP ANHUI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Huanglian Shangqing Tablet is a kind of this product that is a film-coated tablet, which is yellowish-brown to brown after removing the film-coat; it has a fragrant smell and a bitter taste. In the production process of Huanglian Shangqing Tablets, the sugar-coated tablets occasionally appear lobes or mottling in areas with large temperature and humidity changes, and need to go through multiple processes such as tablet pressing, syrup coating isolation layer, outer layer coating, and polishing. There are many steps, the process is complicated, and the production cost is high. Therefore, we plan to change sugar-coated tablets to film-coated tablets

Method used

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  • Huanglian Shangqing tablets and preparation method thereof
  • Huanglian Shangqing tablets and preparation method thereof
  • Huanglian Shangqing tablets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0175] Embodiment 1, a kind of Huanglian Shangqing tablet, this Huanglian Shangqing tablet consists of the following raw materials and auxiliary materials:

[0176] Coptis 5 parts by weight, rhubarb 160 parts by weight, forsythia 40 parts by weight, mint 20 parts by weight

[0177] Inula 10 parts by weight, Scutellaria baicalensis 40 parts by weight, Nepeta panicle 40 parts by weight, Gardenia 40 parts by weight

[0178] 20 parts by weight of windproof, 20 parts by weight of gypsum, 40 parts by weight of bellflower, 20 parts by weight of cork

[0179] 40 parts by weight of Angelica dahurica, 20 parts by weight of licorice, 20 parts by weight of Chuanxiong, 80 parts by weight of chrysanthemum

[0180] Fried Vitex 40 parts by weight Micropowder silica gel 0.2-0.4 parts by weight Magnesium stearate 0.2-0.4 parts by weight

[0181] 1-3 parts by weight of povidone K30, 2.7-4.7 parts by weight of dextrin, and 2.7-4.7 parts by weight of starch.

[0182] In the present embodiment, ...

Embodiment 2

[0197] Embodiment 2, the Huanglian Shangqing tablet has the following raw materials and auxiliary materials:

[0198] Coptis 5 parts by weight, rhubarb 160 parts by weight, forsythia 40 parts by weight, mint 20 parts by weight

[0199] Inula 10 parts by weight, Scutellaria baicalensis 40 parts by weight, Nepeta panicle 40 parts by weight, Gardenia 40 parts by weight

[0200] 20 parts by weight of windproof, 20 parts by weight of gypsum, 40 parts by weight of bellflower, 20 parts by weight of cork

[0201] 40 parts by weight of Angelica dahurica, 20 parts by weight of licorice, 20 parts by weight of Chuanxiong, 80 parts by weight of chrysanthemum

[0202] Fried Vitex 40 parts by weight Micropowder silica gel 0.2 parts by weight Magnesium stearate 0.2 parts by weight

[0203] 1 part by weight of povidone K30, 2.7 parts by weight of dextrin, and 2.7 parts by weight of starch.

[0204] In the present embodiment, the Huanglian Shangqing Tablets consist of the following preparati...

Embodiment 3

[0219] Embodiment 3, this Huanglian Shangqing Tablet has the following raw materials and auxiliary materials:

[0220] Coptis 5 parts by weight, rhubarb 160 parts by weight, forsythia 40 parts by weight, mint 20 parts by weight

[0221] Inula 10 parts by weight, Scutellaria baicalensis 40 parts by weight, Nepeta panicle 40 parts by weight, Gardenia 40 parts by weight

[0222] 20 parts by weight of windproof, 20 parts by weight of gypsum, 40 parts by weight of bellflower, 20 parts by weight of cork

[0223] 40 parts by weight of Angelica dahurica, 20 parts by weight of licorice, 20 parts by weight of Chuanxiong, 80 parts by weight of chrysanthemum

[0224] Fried Vitex 40 parts by weight Micropowder silica gel 0.4 parts by weight Magnesium stearate 0.4 parts by weight

[0225] 3 parts by weight of povidone K30, 4.7 parts by weight of dextrin, and 4.7 parts by weight of starch.

[0226] In the present embodiment, the Huanglian Shangqing Tablets consist of the following prepara...

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Abstract

The invention discloses Huanglian Shangqing tablets and a preparation method thereof. The Huanglian Shangqing tablets are prepared from rhizoma coptidis, rheum officinale, fructus forsythiae, mint, flos inulae, Scutellaria baicalensis, schizonepeta spike, fructus gardeniae, radix saposhnikoviae, gypsum, radix platycodonis, cortex phellodendri, radix angelicae dahuricae, liquorice root, rhizoma chuanxiong, flos chrysanthemi, fried fructus viticis, aerosil, magnesium stearate, povidone K30, dextrin and starch in a certain proportion. After the sugar-coated tablet is changed into the film-coatedtablet, the production steps can be reduced, and the production time is shortened; the materials are saved, the tablet shape is attractive, and marks are clear; the stability of a preparation is greatly improved; and the situation of cracking or piebaldness caused by large temperature and humidity changes is greatly reduced.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a Huanglian Shangqing Tablet and a preparation method thereof. Background technique [0002] Huanglian Shangqing Tablet is a kind of this product that is a film-coated tablet, which is yellow-brown to brown after removing the film-coat; it is fragrant and bitter, and it is a kind included in the 2010 edition of Chinese Pharmacopoeia. In the production process of Huanglian Shangqing Tablets, the sugar-coated tablets occasionally appear lobes or mottling in areas with large temperature and humidity changes, and need to go through multiple processes such as tablet pressing, syrup coating isolation layer, outer layer coating, and polishing. There are many steps, the process is complicated, and the production cost is high. Therefore, we plan to change the sugar-coated tablets to film-coated tablets. Contents of the invention [0003] The main purpose of the present invention is t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K9/28A61K33/06
CPCA61K9/2009A61K9/2013A61K9/2027A61K9/2059A61K9/28A61K33/06A61K36/232A61K36/236A61K36/238A61K36/28A61K36/287A61K36/346A61K36/484A61K36/534A61K36/538A61K36/539A61K36/634A61K36/708A61K36/718A61K36/744A61K36/756A61K36/85A61K2300/00
Inventor 苏学东李琼陈文训胡小桂
Owner HUIYINBI GROUP ANHUI PHARMA
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