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Pharmaceutical composition containing ginsenoside

A technology of ginsenoside and composition, applied in the field of medicine, can solve the problems of normal cell damage and high toxicity, and achieve the effects of inhibiting proliferation, promoting cell apoptosis, and strong resistance

Pending Publication Date: 2020-01-17
吉林省蔚来生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pharmaceutical composition can effectively inhibit tumor cells, but the pharmaceutical composition has high toxicity to normal cells, so that normal cells will also be damaged. Therefore, a method that can effectively inhibit tumor cells and damage normal cells is proposed. Lower pharmaceutical compositions containing ginsenosides

Method used

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  • Pharmaceutical composition containing ginsenoside
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Examples

Experimental program
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Effect test

Embodiment 1

[0018] A pharmaceutical composition containing ginsenosides, comprising active ingredients of the pharmaceutical composition: ginsenoside Rh2, ophiopogon saponin B, dendrobium polysaccharide, cordycepin and arginine; weigh 65 g of arginine and water of equal quality, stir Evenly, add 220g ginsenoside Rh, 5g Ophiopogon saponin B, 5g dendrobium polysaccharide, 1g cordycepin, heat to 45°C, stir to dissolve, adjust the pH value to 5.6 with an aqueous solution containing 3% hydrochloric acid, add water to the full amount, and stir evenly; then add Activated carbon with a liquid volume of 0.1% (g / ml), stirred for 25 minutes, and decarbonized by coarse filtration; passed through a 0.22 μm filter membrane to obtain a fine filtrate; sterilized under high pressure at 121° C. for 30 minutes, precipitated crystals, and pulverized by a grinder. Then sieve through a 200-mesh sieve to obtain dry powder, inspect, pack, and store.

Embodiment 2

[0020] A pharmaceutical composition containing ginsenosides, comprising the active ingredients of the pharmaceutical composition: ginsenoside Rh2, ophiopogon saponin B, dendrobium polysaccharide, cordycepin and arginine; weigh 70 g of arginine and water of equal quality, stir Evenly, add 25g of ginsenoside Rh2, 8g of ophiopogon saponin, 5g of dendrobium polysaccharide, and 1g of cordycepin, heat to 45°C, stir to dissolve, adjust the pH value to 5.6 with an aqueous solution containing 3% hydrochloric acid, add water to the full amount, and stir evenly; Add activated carbon with a liquid dosage of 0.1% (g / ml), stir for 25 minutes, coarsely filter and decarbonize; pass through a 0.22 μm filter membrane to obtain a fine filtrate; sterilize at 121°C for 30 minutes, precipitate crystals, and pulverize through a grinder , and then sieved through a 200-mesh sieve to obtain dry powder, inspected, packaged, and put into storage.

Embodiment 3

[0022] A pharmaceutical composition containing ginsenosides, comprising the active ingredients of the pharmaceutical composition: ginsenoside Rh2, ophiopogon saponin B, dendrobium polysaccharide, cordycepin and arginine; weigh 70 g of arginine and water of equal quality, stir Evenly, add 25g of ginsenoside Rh2, 8g of ophiopogon saponin, 5g of dendrobium polysaccharide, and 1g of cordycepin, heat to 45°C, stir to dissolve, adjust the pH value to 5.6 with an aqueous solution containing 3% hydrochloric acid, add water to the full amount, and stir evenly; Add activated carbon with a liquid dosage of 0.1% (g / ml), stir for 25 minutes, coarsely filter and decarbonize; pass through a 0.22 μm filter membrane to obtain a fine filtrate; sterilize at 121°C for 30 minutes, precipitate crystals, and pulverize through a grinder , and then sieved through a 200-mesh sieve to obtain dry powder, which is compressed into tablets to obtain tablets.

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Abstract

The invention relates to the technical field of medicines, in particular to a pharmaceutical composition containing ginsenoside. The pharmaceutical composition comprises the following active ingredients in parts by weight: 20 to 25 parts of ginsenoside Rh2, 5 to 10 parts of ophiopogonin B, 5 to 10 parts of dendrobium polysaccharide, 1 to 3 parts of cordycepin and 65 to 70 parts of a stabilizer. The pharmaceutical composition composed of the ginsenoside Rh2, the ophiopogonin B, the dendrobium polysaccharide, the cordycepin and arginine can enhance the immune response function of the body and improve the inhibition of cancer cells. Meanwhile, the dendrobium polysaccharide can repair cells damaged by toxicity of the ginsenoside Rh2 and the ophiopogonin B so as to reduce cell damage.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition containing ginsenoside. Background technique [0002] Cancer is a common and frequently-occurring disease, which poses a serious threat to people's life and health, and has a huge impact on national economic construction. The incidence of cancer in the world and in my country is increasing year by year. In my country, about 1.6 million people are newly diagnosed with cancer and about 1.3 million people die from cancer every year. At the current level of cancer death in our country, 2 people die of cancer every minute in the country, and more than 2,800 people will be killed by cancer every day, which is equivalent to the destruction of a city with a population of one million in one year. [0003] Ginseng belongs to the first-class famous and precious traditional Chinese medicine. Its main functions are: "invigorate vital energy, invigorate the sple...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61K31/704A61K31/7048A61K31/7076A61K47/18A61P35/00
CPCA61K31/704A61K31/7048A61K31/715A61K31/7076A61K47/183A61P35/00A61K2300/00
Inventor 张思明赵爱玲王鹏
Owner 吉林省蔚来生物科技有限公司
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