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Method and device for preparing paper-based micro-fluidic chip

A microfluidic chip and paper-based technology, applied in chemical instruments and methods, laboratory containers, laboratory utensils, etc., can solve the problems of high manufacturing cost and harsh manufacturing environment of paper-based microfluidic chips

Pending Publication Date: 2020-01-21
苏州微湃医疗科技有限公司
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  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the physical and chemical-based preparation methods in the prior art require harsh preparation environments and sophisticated instruments, thus making the preparation cost of paper-based microfluidic chips relatively high

Method used

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  • Method and device for preparing paper-based micro-fluidic chip
  • Method and device for preparing paper-based micro-fluidic chip
  • Method and device for preparing paper-based micro-fluidic chip

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Embodiment Construction

[0034] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments, so that those skilled in the art can better understand the present invention and implement it, but the examples given are not intended to limit the present invention.

[0035] refer to Figure 1-Figure 5 As shown, an embodiment of a method for preparing a paper-based microfluidic chip of the present invention includes the following steps:

[0036] S0, coating the printing plate 6 on the outside of the first cylinder 5;

[0037] S1. Coat the hydrophobic solution 1 on the printing plate 6. In this embodiment, the hydrophobic solution 1 can be made of hydrophobic materials such as polystyrene or polydimethylsiloxane;

[0038] S21, winding the paper base 7 outside the second drum 8;

[0039] S22, the first cylinder 5 and the second cylinder 8 are relatively rotated, and the printing plate 6 is pressed on the paper base 7;

[0040] S23. At the posi...

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Abstract

The invention discloses a preparation method of a paper-based micro-fluidic chip. The preparation method comprises the following steps: S1, coating a printing plate with a hydrophobic solution; S2, pressing a printing plate on the paper base, so that the hydrophobic solution permeates into fiber gaps of the paper base to form hydrophobic walls; S3, drying the paper base. A protruding part is arranged on the surface of the printing plate and is consistent with a pattern of a three-dimensional channel of a micro-fluidic chip needing to be prepared, so that the pattern defines a hydrophobic areaof the micro-fluidic chip needing to be prepared; when the hydrophobic solution is coated on the surface of the paper base by utilizing the attachment of the printing plate and the paper base, the hydrophobic solution can permeate into fiber pores of the paper base to form hydrophobic walls after the hydrophobic solution is in contact with the paper base, and the part, which is not in contact withthe hydrophobic solution, of the paper base still keeps hydrophilic and is used for forming a microfluid channel.

Description

technical field [0001] The invention relates to the field of preparation of microfluidic chips, in particular to a method and device for preparing paper-based microfluidic chips. Background technique [0002] Paper-based microfluidic chip is an emerging microfluidic analysis technology platform, which has the advantages of low cost, simple processing, convenient use and portability, and has great applications in clinical diagnosis, food quality control and environmental monitoring. prospect. Paper-based microfluidic chips use paper as a substrate instead of materials such as silicon, glass, and polymers. This kind of analysis device is called a micro-lab on paper, also known as a microfluidic paper analysis device. It is widely used in clinical diagnosis, food quality, environmental monitoring and other fields. [0003] The preparation process of paper-based microfluidic chips can be divided into physical-based and chemical-based methods. The physical process is mainly to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/502707B01L2200/12
Inventor 栗昕马海波刘新宇翟荣安
Owner 苏州微湃医疗科技有限公司
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