Removal method and removal evaluation method of micro-fluidic chip support materials based on 3D printing

A technology of microfluidic chips and supporting materials, applied in 3D object support structures, additive processing, metal processing equipment, etc., can solve the problems of chip structure damage, chip surface blurring and whitening, etc.

Inactive Publication Date: 2020-02-04
XIDIAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The surface of the 3D printed microfluidic chip treated with 95% ethanol solution showed fuzzy whitening phenomenon, the chip structure was damaged to a certain extent, and the high concentration of ethanol was volatile, and there would be a strong pungent smell during the experiment, which made the experiment Must be done in a fume hood

Method used

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  • Removal method and removal evaluation method of micro-fluidic chip support materials based on 3D printing
  • Removal method and removal evaluation method of micro-fluidic chip support materials based on 3D printing
  • Removal method and removal evaluation method of micro-fluidic chip support materials based on 3D printing

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] See figure 2 , figure 2 It is a schematic flowchart of a method for removing support material of a microfluidic chip based on 3D printing provided by an embodiment of the present invention. The removal of the supporting material of the microfluidic chip can be achieved in the following manner.

[0055] A method for removing a support material of a microfluidic chip based on 3D printing, comprising the steps of:

[0056] (a) using vegetable oil to remove the external support material of the microfluidic chip;

[0057] (b) Using vegetable oil to remove the internal support material of the microfluidic chip.

[0058] In a specific embodiment, the removal of the external support material of the microfluidic chip is completed by heating the microfluidic chip, and then the vegetable oil is injected into the microfluidic chip to complete the microfluidic chip. Removal of support material inside the chip.

[0059] In a specific embodiment, the removal of the external sup...

Embodiment 2

[0062] Please refer to FIG. 1 again. On the basis of the above-mentioned embodiments, this embodiment focuses on a detailed description of the specific process of a method for removing the supporting material of a microfluidic chip based on 3D printing.

[0063] (S10) Using vegetable oil to remove the external support material of the microfluidic chip.

[0064] In a specific embodiment, the vegetable oil is vegetable oil such as peanut oil and rapeseed oil.

[0065] The principle of the embodiments of the present invention is to find a solvent that is similar in polarity and structure to the chemical composition of the support material according to the law of like dissolves like. The main chemical components of the supporting material wax are fatty acids, fatty alcohols and oils. In the embodiment of the present invention, vegetable oil is selected as the solvent, which has the property of being miscible with the wax as vegetable oil, and the vegetable oil has relatively large...

Embodiment 3

[0094] This example describes in detail a method for removing the support material of a microfluidic chip with a specific internal channel shape.

[0095] Using CDA software to design and draw a microfluidic chip with one inlet and three outlets, the 3D printed chip is produced with Projet 3500HD equipment. The cross-sectional shape of the internal channel of the microfluidic chip is rectangular, with width and height respectively 400 microns and 200 microns, the molding material is yellow translucent photosensitive resin, and the support material is 100% wax-type material. Pour the vegetable oil into the tin box and heat it at a constant temperature to 70°C, place the microfluidic chip in the vegetable oil and heat it in a water bath, after heating to 70°C, keep it warm for 20 minutes, and remove the external support material of the microfluidic chip; then , use a rubber hose to connect the entrance of the internal channel of the microfluidic chip with the constant flow pump,...

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Abstract

The invention relates to a removal method and removal evaluation method of micro-fluidic chip support materials based on 3D printing. The removal method comprises the following steps that (a), the external support material of a micro-fluidic chip is removed by using vegetable oil; and (b), the internal support material of the micro-fluidic chip is removed by using vegetable oil. The removal evaluation method comprises the following steps that an evaluation result of the micro-fluidic chip support materials is obtained according to the removal rate of the external support material and the lighttransmittance of the internal support material of the micro-fluidic chip. According to the removal method, the vegetable oil can directly remove the support materials inside and outside the 3D printing micro-fluidic chip, and the requirement of thoroughly removing the support materials is met.

Description

technical field [0001] The invention belongs to the technical field of post-processing of 3D printing technology, and in particular relates to a method for removing a supporting material of a microfluidic chip based on 3D printing and a removal evaluation method. Background technique [0002] In the past ten years, 3D printing has emerged to manufacture microfluidic chips, which is considered a revolution in microfluidics. Projet 3500HD printers are used to print microfluidic chips. During the process of printing chips Two parts of support material, inside and outside, are added to support the internal microfluidic channel and maintain the external structure of the chip. [0003] Support materials have been widely used in 3D printing, and the removal method of support materials is crucial to the final quality of microfluidic chips, but many companies and laboratories do not pay attention to research on the removal methods of support materials. The support material used in 3...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B29C64/40B33Y40/00
CPCB33Y40/00B29C64/40
Inventor 胡波殷朋举续小丁赵磊施红雁田学斌王翀
Owner XIDIAN UNIV
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