Anti-streptococcus agalactiae traditional Chinese medicine extract effective part formula and production process thereof

Abstract

The invention discloses an anti-streptococcus agalactiae traditional Chinese medicine extract effective part formula. The formula is composed of the following raw materials in parts by weight: 100-120parts of a rhubarb root and rhizome extract, 15-25 parts of berberine hydrochloride, 70-90 parts of a baical skullcap root extract, and 75-95 parts of a weeping forsythia capsule extract. Because theberberine hydrochloride content in the prescription is low and the baical skullcap root extract has poor fluidity, on the basis of previous experiments, a production process adopts a manner of performing pre-mixing of a small amount of a filling agent with berberine hydrochloride and the baical skullcap root extract, and then performing total mixing to increase the uniformity and ensure stable drug effects. The test shows that the minimum bacteriostatic concentration of the formula against streptococcus agalactiae is 5.625 [mu]g / mL; and the minimum bactericidal concentration is 31.25 [mu]g / mL, so that the formula shows good antibacterial effects. Therefore, the anti-streptococcus agalactiae traditional Chinese medicine extract with antibacterial effects, non-toxicity and no residue, and being capable of replace antibiotics, and a powder thereof have great significance and broad prospects.

Description

technical field [0001] The invention belongs to the technical field of extraction of traditional Chinese medicines, and in particular relates to a prescription of effective parts of an anti-streptococcus agalactiae traditional Chinese medicine extract and a production process thereof. Background technique [0002] With the rapid development of the breeding industry, the application of antibiotics is becoming more and more extensive, which plays a certain positive role in the prevention and treatment of animal diseases. However, in recent years, the problem of drug resistance caused by the abuse of antibiotics in aquaculture cannot be ignored. Moreover, the long-term and unscientific use of antibiotics in large quantities will also cause heavy metal residues in animal feces, leading to environmental pollution and serious harm to human health. The rapid development of the breeding industry has not only increased the supply of animal products, but also brought food safety issu...

AI Technical Summary

Problems solved by technology

However, in recent years, the problem of drug resistance caused by the abuse of antibiotics in the farming industry cannot be ignored.

Moreover, the long-term and unscientific use of antibiotics in large quantities will also cause heavy metal residues in animal feces, leading to environmental pollution and serious harm to human health. The rapid development of the breeding industry has not only increased the supply of animal products, but also brought food safety issue

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