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Liquid band-aid and preparation method thereof

A band-aid and liquid technology, which is applied in the fields of medical formula, medical science, bandages, etc., can solve the problems that have not been raised, the inability to completely wound, the skin irritation, etc., to achieve rapid repair of skin damage, not easy to mechanical re-injury, high-efficiency antibacterial selective effect

Active Publication Date: 2020-03-06
TIANJIN GOALGEN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1. The film forming speed is slow. When the liquid band-aid is sprayed on the patient's wound, it needs to wait for 3-5 minutes;
[0006] 2. It is highly irritating to the skin but cannot completely sterilize the wound;
[0007] 3. After use, melanin deposits appear on the skin, and the skin repair speed is slow and the effect is poor;
[0008] 4. The viscosity is difficult to control. When the viscosity is too high, it is easy to cause mechanical re-damage during replacement; if the viscosity is too small, it is easy to leave the affected area
However, a technical solution for a liquid band-aid that has fast film-forming speed, moderate viscosity, good bactericidal properties, and can selectively and quickly repair skin damage has not yet been proposed.

Method used

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  • Liquid band-aid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] 1. A liquid band-aid, comprising 50 parts by weight of butyl acetate, 17 parts of benzyl alcohol, 14 parts of ethyl acetate, 5 parts of nitrocellulose, 3 parts of propylene glycol, 1 part of polyethylene glycol and ethyl tocopherol 1 part of acid ester; Wherein, the molecular weight of polyethylene glycol is 3000.

[0049] 2. A preparation method for liquid band-aid, comprising the following steps:

[0050] S1. Weigh butyl acetate, benzyl alcohol, ethyl acetate and propylene glycol according to the proportion, place them in a container and mix them uniformly to obtain a mixed solution A;

[0051] S2. Weigh polyethylene glycol and tocopheryl acetate according to the proportion, add in the mixed solution A and mix evenly to obtain the mixed solution B;

[0052] S3. Weigh the nitrocellulose according to the proportion, add it into the mixed solution B and mix evenly, let it stand until the air bubbles disappear, and obtain a liquid band-aid. After testing, the pH of the liq...

Embodiment 2

[0054] 1. A liquid band-aid, comprising 55 parts by weight of butyl acetate, 19 parts of benzyl alcohol, 15 parts of ethyl acetate, 10 parts of nitrocellulose, 5 parts of propylene glycol, 2 parts of polyethylene glycol and B-tocopheryl 2 parts of acid ester; Wherein, the molecular weight of polyethylene glycol is 6000.

[0055] 2. A preparation method for liquid band-aid, comprising the following steps:

[0056] S1. Weigh butyl acetate, benzyl alcohol, ethyl acetate and propylene glycol according to the proportion, place them in a container and mix them uniformly to obtain a mixed solution A;

[0057] S2. Weigh polyethylene glycol and tocopheryl acetate according to the proportion, add in the mixed solution A and mix evenly to obtain the mixed solution B;

[0058] S3. Weigh the nitrocellulose according to the proportion, add it to the mixed solution B and mix evenly, and let it stand until the bubbles disappear to obtain a liquid band-aid. After testing, the pH of the liquid...

Embodiment 3

[0060] 1. A liquid band-aid, comprising 52 parts by weight of butyl acetate, 18 parts of benzyl alcohol, 14.5 parts of ethyl acetate, 7 parts of nitrocellulose, 4 parts of propylene glycol, 1.5 parts of polyethylene glycol and B-tocopherol 1.5 parts of acid ester; Wherein, the molecular weight of polyethylene glycol is 4000.

[0061] 2. A preparation method for liquid band-aid, comprising the following steps:

[0062] S1. Weigh butyl acetate, benzyl alcohol, ethyl acetate and propylene glycol according to the proportion, place them in a container and mix them uniformly to obtain a mixed solution A;

[0063] S2. Weigh polyethylene glycol and tocopheryl acetate according to the proportion, add in the mixed solution A and mix evenly to obtain the mixed solution B;

[0064] S3. Weigh the nitrocellulose according to the proportion, add it to the mixed solution B and mix evenly, and let it stand until the bubbles disappear to obtain a liquid band-aid. After testing, the pH of the l...

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Abstract

The invention relates to the field of medical dressings, in particular to a liquid band-aid, which comprises butyl acetate, benzyl alcohol, ethyl acetate, nitrocellulose, propylene glycol, polyethylene glycol, tocopheryl acetate and lipidosome, and the lipidosome comprises cytokines, antibacterial nanoparticles, an activity protective agent and phospholipid. Wherein the cell factors comprise one or two of EGF and FGF; wherein the antibacterial nano particles comprise nano silver; wherein the activity protective agent comprises one or two of tetrahydropyrimidine and trehalose; wherein the phospholipid comprises one or more of soybean lecithin, hydrogenated soybean phospholipid, dilauroyl lecithin and distearoyl phosphatidyl glycerol; the invention further discloses a method for preparing the liquid band-aid. The liquid band-aid is moderate in viscosity and not prone to falling off, and a wound cannot be torn off when the liquid band-aid is taken down; the liquid band-aid has good isolation and bactericidal properties, and can fundamentally realize rapid repair of skin injury.

Description

technical field [0001] The invention relates to the field of medical dressings, in particular to a liquid band-aid and a preparation method thereof. Background technique [0002] In daily life, situations of skin injury are unavoidable, such as daily cuts, burns and abrasions. Wound repair is a complex process involving multi-cells and multi-cytokines. The use of wound dressings plays an important role in the treatment or repair of wounds. It is beneficial to protect wounds from external aggressions, including physical contact injuries and microorganisms such as bacteria. re-infection, and then use the body's own healing and repair ability to wait for the wound to heal. [0003] Traditional Band-Aid is currently the most commonly used wound dressing, widely used in the treatment of small wounds on the human body, but it has many disadvantages, such as poor adhesion, poor air permeability, and easy to cause whitening of the skin near the wound, which makes the liquid Band-Ai...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/00A61L26/0004A61L26/0019A61L26/0023A61L26/0047A61L26/0061A61L26/0066A61L2300/104A61L2300/404A61L2300/412A61L2400/12C08L1/18C08L71/02C08L89/00
Inventor 马艳芳梁青梁兰
Owner TIANJIN GOALGEN BIOTECH
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