Method for synthesizing 2-isopropylnaphthalene

Abstract

The invention discloses a method for synthesizing 2-isopropylnaphthalene, and belongs to the technical field of organic synthesis application. Naphthalene is preheated to serve as a fluid A, an alkylation reagent serves as a fluid B, a chloroaluminate ionic liquid serves as a fluid C, and the three fluids are synchronously fed into a micro-reactor; the fluids A, B and C react in the micro-reactoraccording to a certain molar ratio at a controlled flow rate, and the 2-isopropylnaphthalene product is obtained after a discharged liquid is treated. The method is simple and convenient to operate, does not use an organic solvent, and is safe, controllable and environment-friendly in process, the catalyst is easy to separate, the naphthalene conversion rate is 100%, the selectivity of the product2-isopropylnaphthalene is 98% or above, and the 2-isopropylnaphthalene product can be continuously produced.

Description

technical field

[0001] The invention belongs to the technical field of organic synthesis applications, and more specifically relates to a method for synthesizing 2-isopropylnaphthalene. Background technique

[0002] In my country, tar naphthalene is mainly extracted from coal tar (the annual production capacity is about 15 million tons, of which naphthalene accounts for about 10-12%). In 2009, the annual production capacity of industrial naphthalene reached 200,000 tons, and the annual output of refined naphthalene reached 100,000 tons. It is very important to develop downstream high value-added products of naphthalene.

[0003] A bicyclic aromatic hydrocarbon with an alkyl group attached to the naphthalene ring is called monoalkylnaphthalene, which is an important chemical raw material or an organic synthesis intermediate. Among them, β-isopropylnaphthalene is the raw material for synthesizing β-naphthol, and there are more than 20 kinds of dye intermediates directly synt...

Examples

Embodiment 1

[0042] Such as figure 1 As shown, the device for synthesizing styrenated phenol in this embodiment includes preheating pipe, metering pump, microreactor (continuous flow microchannel reactor), and the microchannel cross-sectional equivalent diameter of microreactor in this embodiment is 0.5mm , the microchannel tube length is 100m.

[0043] The steps of synthesizing styrenated phenol in the present embodiment are as follows:

[0044] (1) Naphthalene is heated to 90 DEG C and kept warm by a preheater as fluid A; 2-bromopropane is used as fluid B at normal temperature; triethylamine heptachlorodialuminate ionic liquid is used as fluid C at normal temperature; wherein, The molar ratio of naphthalene: 2-bromopropane: chloroaluminate ionic liquid is 1: 1.04: 0.6;

[0045] The volume flow rate of naphthalene is controlled by a metering pump to be 2.5ml / min, the volume flow rate of 2-bromopropane is 2.0ml / min and the volume flow rate of chloroaluminate ionic liquid catalyst is 3ml / ...

Embodiment 2

[0050] Such as figure 1 As shown, the device for synthesizing styrenated phenol in this embodiment includes preheating pipe, metering pump, microreactor (continuous flow microchannel reactor), and the microchannel cross-sectional equivalent diameter of microreactor in this embodiment is 0.6mm , the microchannel tube length is 120m.

[0051] The steps of synthesizing styrenated phenol in the present embodiment are as follows:

[0052] (1) Naphthalene is heated to 95 DEG C and kept warm by a preheater as fluid A; 2-bromopropane is used as fluid B at normal temperature; triethylamine heptachlorodialuminate ionic liquid is used as fluid C at normal temperature; wherein, The molar ratio of naphthalene: 2-bromopropane: chloroaluminate ionic liquid is 1: 1.04: 1.2;

[0053] The volume flow rate of naphthalene is 3ml / min, the volume flow rate of 2-bromopropane is 2.3ml / min, and the volume flow rate of chloroaluminate ionic liquid catalyst is 6ml / min through the metering pump, and th...

Embodiment 3

[0056] Such as figure 1 As shown, the device for synthesizing styrenated phenol in this embodiment includes preheating pipe, metering pump, microreactor (continuous flow microchannel reactor), and the microchannel cross-sectional equivalent diameter of microreactor in this embodiment is 0.8mm , the microchannel tube length is 150m.

[0057] The steps of synthesizing styrenated phenol in the present embodiment are as follows:

[0058] (1) Naphthalene is heated to 90 DEG C and kept warm by a preheater as fluid A; 2-bromopropane is used as fluid B at normal temperature; triethylamine heptachlorodialuminate ionic liquid is used as fluid C at normal temperature; wherein, The molar ratio of naphthalene: 2-bromopropane: chloroaluminate ionic liquid is 1: 1.04: 1.8;

[0059] The volume flow rate of naphthalene is controlled by a metering pump to be 3.5ml / min, the volume flow rate of 2-bromopropane is 2.7ml / min and the volume flow rate of chloroaluminate ionic liquid catalyst is 9ml / ...

technical field

[0001] The invention belongs to the technical field of organic synthesis applications, and more specifically relates to a method for synthesizing 2-isopropylnaphthalene. Background technique

[0002] In my country, tar naphthalene is mainly extracted from coal tar (the annual production capacity is about 15 million tons, of which naphthalene accounts for about 10-12%). In 2009, the annual production capacity of industrial naphthalene reached 200,000 tons, and the annual output of refined naphthalene reached 100,000 tons. It is very important to develop downstream high value-added products of naphthalene.

[0003] A bicyclic aromatic hydrocarbon with an alkyl group attached to the naphthalene ring is called monoalkylnaphthalene, which is an important chemical raw material or an organic synthesis intermediate. Among them, β-isopropylnaphthalene is the raw material for synthesizing β-naphthol, and there are more than 20 kinds of dye intermediates directly synt...

Examples

Embodiment 1

[0042] Such as figure 1 As shown, the device for synthesizing styrenated phenol in this embodiment includes preheating pipe, metering pump, microreactor (continuous flow microchannel reactor), and the microchannel cross-sectional equivalent diameter of microreactor in this embodiment is 0.5mm , the microchannel tube length is 100m.

[0043] The steps of synthesizing styrenated phenol in the present embodiment are as follows:

[0044] (1) Naphthalene is heated to 90 DEG C and kept warm by a preheater as fluid A; 2-bromopropane is used as fluid B at normal temperature; triethylamine heptachlorodialuminate ionic liquid is used as fluid C at normal temperature; wherein, The molar ratio of naphthalene: 2-bromopropane: chloroaluminate ionic liquid is 1: 1.04: 0.6;

[0045] The volume flow rate of naphthalene is controlled by a metering pump to be 2.5ml / min, the volume flow rate of 2-bromopropane is 2.0ml / min and the volume flow rate of chloroaluminate ionic liquid catalyst is 3ml / ...

Embodiment 2

[0050] Such as figure 1 As shown, the device for synthesizing styrenated phenol in this embodiment includes preheating pipe, metering pump, microreactor (continuous flow microchannel reactor), and the microchannel cross-sectional equivalent diameter of microreactor in this embodiment is 0.6mm , the microchannel tube length is 120m.

[0051] The steps of synthesizing styrenated phenol in the present embodiment are as follows:

[0052] (1) Naphthalene is heated to 95 DEG C and kept warm by a preheater as fluid A; 2-bromopropane is used as fluid B at normal temperature; triethylamine heptachlorodialuminate ionic liquid is used as fluid C at normal temperature; wherein, The molar ratio of naphthalene: 2-bromopropane: chloroaluminate ionic liquid is 1: 1.04: 1.2;

[0053] The volume flow rate of naphthalene is 3ml / min, the volume flow rate of 2-bromopropane is 2.3ml / min, and the volume flow rate of chloroaluminate ionic liquid catalyst is 6ml / min through the metering pump, and th...

Embodiment 3

[0056] Such as figure 1 As shown, the device for synthesizing styrenated phenol in this embodiment includes preheating pipe, metering pump, microreactor (continuous flow microchannel reactor), and the microchannel cross-sectional equivalent diameter of microreactor in this embodiment is 0.8mm , the microchannel tube length is 150m.

[0057] The steps of synthesizing styrenated phenol in the present embodiment are as follows:

[0058] (1) Naphthalene is heated to 90 DEG C and kept warm by a preheater as fluid A; 2-bromopropane is used as fluid B at normal temperature; triethylamine heptachlorodialuminate ionic liquid is used as fluid C at normal temperature; wherein, The molar ratio of naphthalene: 2-bromopropane: chloroaluminate ionic liquid is 1: 1.04: 1.8;

[0059] The volume flow rate of naphthalene is controlled by a metering pump to be 3.5ml / min, the volume flow rate of 2-bromopropane is 2.7ml / min and the volume flow rate of chloroaluminate ionic liquid catalyst is 9ml / ...

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