Drug carrier, drug structure, use of drug carrier, preparation methods of drug carrier and drug structure, and method for inhibiting helicobacter pylori by using drug structure

Abstract

The present invention provides a drug carrier, a drug structure, a use of the drug carrier, preparation methods of the drug carrier and the drug structure, and a method for inhibiting helicobacter pylori by using the drug structure. The drug carrier comprises a negatively charged polymer, chitosan, and magnetic particles. The use of the drug carrier is to prepare a drug for inhibiting the helicobacter pylori. The drug structure comprises a negatively charged polymer, chitosan, magnetic particles, and active ingredients. The preparation method of the drug structure comprises the following steps: solutions having components of the drug structure are provided and the solutions are mixed into an initial solution, and the components in the initial solution react to form drug structure particles. The method for inhibiting the helicobacter pylori by using the drug structure is to put an effective dose of the drug structure to the helicobacter pylori population. Through the above-mentioned drug carrier and drug structure, therapeutic effects of the drug carrier or the drug structure can be further improved.

Description

technical field [0001] The present invention relates to a drug carrier, a drug structure, its use, its preparation method and a method for using it to inhibit pylori bacteria, in particular to a drug carrier capable of being guided by an external magnetic field and a drug structure containing the drug carrier. Background technique [0002] Pylori is a bacterium that lives in the stomach and duodenum. According to epidemiological studies, it has been confirmed that pylori is mainly transmitted through contaminated drinking water or food. In underdeveloped and developing countries, the infection rate of pylori is as high as 80-90% among the population under the age of twenty. [0003] When the human body is infected by pylori bacteria, the pylori bacteria will adhere to the gastric epithelial cell layer of the human body, and the pylori bacteria will convert a very small amount of urea present in the human stomach into alkaline ammonia through the urease secreted by it to Mai...

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Problems solved by technology

[0010] The aforementioned patents have disclosed a variety of microsphere drug carriers or microsphere drug structures that can be used to inhibit pylori, but how to further improve the therapeutic effect of drug carriers or drug structures so as to reduce the number of drugs that patients take in a single dose And the side effects of patients due to overdose of drugs, there are still unresolved problems

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