Low-foam flushing fluid and application thereof

A flushing liquid and emulsifier technology, applied in detergent compositions, detergent compounding agents, surface active detergent compositions, etc., can solve the problems of carrying pollution interference test results, unsatisfactory application effect, blockage of flow path system, etc. , to achieve the effect of facilitating industrial production, low cost and improving defoaming

Pending Publication Date: 2020-05-29
SHANGHAI SUNBIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few studies on cleaning solutions suitable for coagulation analyzers. The cleaning agents for coagulation analyzers disclosed in some patents are acidic, and the compatibility with anhydrous flushing automatic coagulation analyzers is not optimal, and There is corrosion to the instrument; there are also two kinds of cleaning solutions suitable for automatic coagulation analyzers without water flushing. The two cleaning solutions must be used together, and the pH range of the two can be controlled to ensure the cleaning effect. The cleaning solution X1 It also plays a flushing role, so the cleaning solution X1 is not effective when used in conjunction with other cleaning solutions
[0004] At present, most of the waterless flushing automatic coagulation analyzers occupying the domestic market are imported, such as STAGO automatic coagulation analyzer, IL ACL TOP series automatic coagulation analyzer, etc., based on the consideration of compatibility, safety and other factors, flushing Liquid mainly depends on imported products or domestic repackaged products of imported raw liquid, which are expensive and costly
However, the actual application effect of domestically produced and supplied cleaning fluids or flushing fluids is not ideal, and some are specially matched with their respective instruments or cleaning fluids; some cause blockage or corrosion to the flow path system of the instrument, which increases the replacement frequency of equipment components; In some cases, the carryover contamination introduced by the flushing fluid interferes with the test results, etc.

Method used

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  • Low-foam flushing fluid and application thereof
  • Low-foam flushing fluid and application thereof
  • Low-foam flushing fluid and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Mix sulfonated emulsifier S-15, AMA LF70, isomerized tridecanol polyoxyethylene ether E1310, sodium chloride and water, stir at room temperature until the solution becomes clear, and prepare a flushing solution. Each 1L of the flushing solution contains: sulfonate Emulsifier S-15 450mg, AMALF70 100mg, E1310 300mg, sodium chloride 600mg.

Embodiment 2

[0038] Mix Amulan DF22, AMA LF40, isotridecyl alcohol polyoxyethylene ether E1308, potassium chloride and water, stir at room temperature until the solution becomes clear, and prepare a flushing solution. Each 1L of the flushing solution contains: Amulan DF22 300mg, AMA LF40 150mg , E1308 200mg, potassium chloride 600mg.

Embodiment 3

[0055] Embodiment 3 and the comparison of listed product physicochemical index

[0056] (1) Use pH meter, digital conductivity meter and Roche foam meter respectively to the original imported rinsing solution, domestic rinsing solution, comparative examples 1 to 8, and Example 1 of the present invention and Example 2. After 1 month, 4 months, and 6 months, the appearance, pH value, electrical conductivity and foam performance of the flushing solution were measured, and the results are shown in Table 1.

[0057] Table 1 Physicochemical indicators of flushing fluid

[0058]

[0059] The implementation results in Table 1 show that the physical and chemical properties of the flushing liquid provided by the present invention are similar to those of the original imported flushing liquid, while the foaming property is significantly lower than that of the commercially available flushing liquid, and the stability is good.

[0060] (2) Under the same working conditions, the original...

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PUM

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Abstract

The invention relates to the technical field of medical instrument cleaning, and in particular, relates to low-foam flushing fluid and an application thereof. The low-foam flushing fluid provided by the invention comprises an emulsifier, a zwitterionic surfactant, a nonionic surfactant, a neutral washing-assisting electrolyte and water. The low-foam flushing fluid at least has the following advantages: (1) the low-foam flushing fluid is low in foam and good in cleaning effect; (2) pipelines and the like of equipment parts are not blocked and corroded, and the replacement frequency of the equipment parts is reduced; (3) the result of a determination item is not influenced, and the accuracy and precision reach or are superior to the level of original imported flushing fluid; (4) the steps are simple, the operation is simple, and industrial production is facilitated; and (5) the stability is good, the cost is low, and imported products can be replaced.

Description

technical field [0001] The invention relates to the technical field of medical device cleaning, in particular to a low-foam flushing liquid and its application. Background technique [0002] The coagulation analyzer is used to clinically measure the content of various components in human blood, quantitative biochemical analysis results, and provide reliable digital evidence for clinical diagnosis of various diseases in patients. It is a necessary routine testing equipment for clinical practice. The accuracy of the test results of the coagulation analyzer directly affects the doctor's diagnosis of the patient's disease. Usually, in the process of using a fully automatic coagulation analyzer for detection, first of all, it is necessary to use cleaning solution, pure water or rinsing solution to clean and rinse the probes, pipes, etc. in a short period of time, and quickly enter the next detection process ;Secondly, due to the relatively large difference between human blood co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C11D1/94C11D3/04C11D3/60G01N33/49G01N35/00
CPCC11D1/94C11D3/046G01N33/49G01N35/00C11D1/88C11D1/72C11D1/29
Inventor 谢永华侯冬梅
Owner SHANGHAI SUNBIO TECH
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