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Skin disease traditional Chinese medicine composition capable of being used for complex eczema and dermatitis and preparation method therefor

A dermatological and complex technology, applied in skin diseases, drug combinations, pharmaceutical formulations, etc., can solve problems such as side effects that cannot be ignored, unstable efficacy, short action time, etc., and achieves inhibition of microvascular expansion, allergic itching and edema. The effect of inhibiting the release of histamine

Active Publication Date: 2020-07-10
张琰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these therapeutic drugs and dosage forms can achieve a certain effect, the curative effect is unstable, the action time is short, drug resistance is easy to occur, and the disease recurs, and the side effects cannot be ignored.

Method used

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  • Skin disease traditional Chinese medicine composition capable of being used for complex eczema and dermatitis and preparation method therefor
  • Skin disease traditional Chinese medicine composition capable of being used for complex eczema and dermatitis and preparation method therefor
  • Skin disease traditional Chinese medicine composition capable of being used for complex eczema and dermatitis and preparation method therefor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] A traditional Chinese medicine composition for complex eczema and dermatitis, made of the following raw materials in parts by weight: 18 parts of Fructus Cnidii, 9 parts of Notopterygium, 9 parts of Schizonepeta, 1 part of Borneolum, 18 parts of Sophora flavescens, comfrey 27 parts, gallnut 6 parts, Kochia chinensis 9 parts, Sichuan pepper 9 parts.

[0044] Preparation method: Take the medicinal materials Cnidium Fructus Cnidii, Notopterygium Nepeta, Sophora Sophora, Comfrey, Galla Chinensis, Kochia Kochia, Chuanjiao, reflux extract with 95% ethanol, concentrate under reduced pressure to 3g crude drug / mL, add 0.3% CMC- Dilute the Na solution to 1g crude drug / mL, dissolve the very fine powder of borneol in a small amount of ethanol, add it to the diluent and mix evenly to obtain the preparation.

Embodiment 2

[0046] A traditional Chinese medicine composition for complex eczema and dermatitis, made of the following raw materials in parts by weight: 10 parts of Fructus Cnidii, 5 parts of Notopterygium, 5 parts of Nepeta, 0.1 part of Borneolum, 5 parts of Sophora flavescens, and Comfrey 10 parts, gallnut 5 parts, Kochia chinensis 5 parts, Chuanjiao 5 parts.

[0047] Preparation method: Take the medicinal materials Cnidium Fructus Cnidii, Notopterygium Nepeta, Sophora Sophora, Comfrey, Galla Chinensis, Kochia Kochia, Chuanjiao, reflux extract with 95% ethanol, concentrate under reduced pressure to 3g crude drug / mL, add 0.3% CMC- Dilute the Na solution to 1g crude drug / mL, dissolve the very fine powder of borneol in a small amount of ethanol, add it to the diluent and mix evenly to obtain the preparation.

Embodiment 3

[0049] A traditional Chinese medicine composition for complex eczema and dermatitis, made of the following raw materials in parts by weight: 20 parts of Fructus Cnidii, 15 parts of Notopterygium, 15 parts of Nepeta, 3 parts of Borneolum, 20 parts of Sophora flavescens, and Comfrey 30 parts, gallnut 10 parts, Kochia chinensis 15 parts, Chuanjiao 15 parts.

[0050]Preparation method: Take the medicinal materials Cnidium Fructus Cnidii, Notopterygium Nepeta, Sophora Sophora, Comfrey, Galla Chinensis, Kochia Kochia, Chuanjiao, reflux extract with 95% ethanol, concentrate under reduced pressure to 3g crude drug / mL, add 0.3% CMC- Dilute the Na solution to 1g crude drug / mL, dissolve the very fine powder of borneol in a small amount of ethanol, add it to the diluent and mix evenly to obtain the preparation.

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Abstract

The invention discloses a skin disease traditional Chinese medicine composition capable of being used for complex eczema and dermatitis and a preparation method therefor, and relates to the technicalfield of medicines for treating skin eczema and dermatitis, aims to solve the technical problems that the curative effect is instable, the acting time is relatively short, drug resistance is easy to generate, the diseases are easy to relapse, and side effects are numerous by using drugs in the prior art, and mainly aims at steroid-dependent eczema and dermatitis easy to relapse, and the like aftertreatment with existing drugs. According to the technical scheme, the skin disease traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1-35 partsof fructus cnidii, 1-35 parts of rhizoma notopterygii, 1-35 parts of herba schizonepetae, 0.1-10 parts of borneol, 1-35 parts of radix sophorae flavescentis, 1-35 parts of radix lithospermi, 1-35 parts of galla chinensis, 1-35 parts of fructus kochiae and 1-35 parts of pericarpium zanthoxyli bungeani.

Description

technical field [0001] The invention relates to the technical field of medicines for treating skin diseases, in particular to a traditional Chinese medicine composition for skin diseases that can be used for complex eczema and dermatitis and a preparation method thereof. Background technique [0002] Eczema is a skin inflammation caused by various factors such as the environment and the body itself. The disease can occur in any season and at any age. It is clinically manifested as polymorphic skin lesions. damp place. Skin pimple-like is the basic form of eczema, which is diverse in different patients. There are often local dark red macules, blisters, severe itching, easy to rupture when scratched, accompanied by exudation, and has been combined with chronic infection. Some patients have recurrent attacks. After long-term lesions, the skin is hypertrophic and rough, which not only affects the appearance, but also causes greater physical distress and psychological pressure f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61P17/00A61P17/04A61P37/08A61K31/045A61K35/64
CPCA61K31/045A61K35/64A61K36/185A61K36/234A61K36/237A61K36/30A61K36/489A61K36/538A61K36/758A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P17/00A61P17/04A61P37/08A61K2300/00
Inventor 张琰姜维石磊文一丁
Owner 张琰
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