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Detection system and method

A detection system and technology for measuring objects, applied in the field of detection, can solve the problems of low reaction efficiency of antibodies and antigens, and achieve the effects of shortening incubation time, avoiding pollution and improving efficiency

Pending Publication Date: 2020-07-10
四川丹诺迪科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At this time, the flow of the sample to be tested in the channel is mainly laminar flow, the reaction efficiency between the antibody and the antigen is low, and a long incubation is required to obtain the result of the immunological measurement

Method used

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Embodiment Construction

[0033] The technical solutions in the embodiments of the present application will be described below with reference to the drawings in the embodiments of the present application.

[0034] In the immunoassay, the incubation reaction of antigen and antibody will be carried out, and the incubation process is a kinetic process of competitive binding. The efficiency of specific binding of antigens and antibodies is millions to billions of times that of non-specific binding. For example, when a specific antibody competes with a non-specific antibody, that is, for the antigen to be measured, both the specific antibody and the non-specific antibody want to bind to the antigen, while the specific antibody and the non-specific antibody are competing relation.

[0035]Therefore, under the condition of the same reaction efficiency, the antigen will be fully and specifically combined with the specific antibody over time, so as to determine the amount of the antigen corresponding to the sp...

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Abstract

The invention provides a detection system and method, and is applied to immunoassay. The detection system comprises microfluidic equipment, a controller, an ultrasonic generator and a measuring device; the controller is respectively connected with the ultrasonic generator and the measuring device; a micro-channel is arranged in the micro-fluidic equipment, at least one reaction position is arranged in the micro-channel, and the reaction position is used for placing a known test object; the controller is used for controlling the ultrasonic generator to generate ultrasonic waves, the coverage range of the ultrasonic waves comprises at least one reaction position in the micro-channel, and the ultrasonic waves are used for improving the reaction efficiency of the known test object and a to-be-measured object; the measuring device is used for measuring the tracer agent state of the reaction position after the reaction and returning the tracer agent state to the controller, and the tracer agent state of the reaction position is used for representing the quantity of the to-be-measured object in the to-be-measured sample; and the controller is also used for outputting a detection result corresponding to the to-be-detected object in the to-be-detected sample according to the tracer agent state of the reaction position so that the immunodetection efficiency is improved.

Description

technical field [0001] The present application relates to the detection field, in particular, to a detection system and method. Background technique [0002] The immune system is composed of immune organs, immune cells, immune molecules, and lymphatic circulation network. The stage of tumors and the degree of allergies are closely related to the immune system. Therefore, immune tests can be used to measure the amount of antigens and antibodies in the immune system to judge the state of the immune system. In the immunoassay, by incubating the antigen and the sample, the specific antibody is combined with the antigen during the incubation process, so that the amount of the antigen or antibody to be measured can be determined. [0003] In the prior art, microfluidic chips are often used for immunoassays, and microchannels with small dimensions are arranged in the microfluidic chips to make liquid flow in the channels by using capillary phenomenon. At this time, the flow of th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N35/00G01N35/02G01N33/58G01N33/53G01N21/64
CPCG01N21/6428G01N33/5302G01N33/582G01N35/00G01N35/02G01N2035/00158
Inventor 廖常宇
Owner 四川丹诺迪科技有限公司
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