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Method for preparing propyl propionate by using recycled n-propanol

A technology of propyl propionate and n-propanol, which is applied in the field of preparing propyl propionate by recovering n-propanol, can solve the difficulty of separating propyl propionate, the low yield of propyl propionate, the decline in utilization rate, etc. problems, to achieve the effect of reduced dosage, high safety and increased productivity

Pending Publication Date: 2020-07-17
LEPING RUISHENG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is obvious shortcoming in this technological method, and its shortcoming mainly shows in the following aspects: produce water in the esterification process, its main raw material propionic acid and n-propanol are easily soluble in the water of generation, cause unreacted raw material and product propionic acid Difficult separation of propyl ester, low yield of propyl propionate
In addition, using n-propanol and propionic acid as raw materials requires a large excess of n-propanol or propionic acid, so that the reaction will proceed in a direction that is beneficial to n-propyl propionate, so the utilization rate of propionic acid or n-propanol will decrease, and it will continue to repeat Applying will increase energy consumption at the same time

Method used

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preparation example Construction

[0028] The invention provides a kind of preparation method of reclaiming n-propanol to prepare propyl propionate, comprising the following steps:

[0029] Under anhydrous conditions, the recovered n-propanol, anhydrous aluminum trichloride and aluminum flakes are mixed for a reflux reaction to obtain a reflux reaction product, which includes aluminum n-propoxide;

[0030] The reflux reaction product is mixed with propionaldehyde to carry out the Tischenko, V. reaction to obtain the Tischenko, V. reaction product;

[0031] The Tischenko, V. reaction product was distilled and rectified in sequence to obtain propyl propionate.

[0032] In the present invention, unless otherwise specified, the raw materials used are conventional commercially available products in this field.

[0033] In the present invention, under anhydrous conditions, the recovered n-propanol, anhydrous aluminum trichloride and aluminum flakes are mixed for reflux reaction to obtain a reflux reaction product, a...

Embodiment 1

[0049] Put 100g of n-propanol into the dry reaction bottle, replace the air with nitrogen three times, and then put in 1.33g of aluminum flakes with a specific surface area of ​​1.1cm 2 / g, and 0.3g of aluminum trichloride, at a heating rate of 2°C / min, the temperature was raised from 25°C to 97°C for reflux reaction for 3h, the temperature was lowered to 10°C, and the cooling rate was 2°C / min, and 600g of acrylic acid was added dropwise Aldehyde, and Tischenko, V. reaction at 10°C for 3h, atmospheric distillation at 80-99°C, reflux ratio 3:1 for 5h, recovery of n-propanol and crude propyl propionate, and crude Propyl propionate was rectified for 5 hours at 100-130°C with a reflux ratio of 5:1 to obtain 570g of propyl propionate product.

[0050] In this embodiment, based on the quality of propionaldehyde, it can be seen through calculation that the yield of propyl propionate is 95%, and the purity is 99%.

Embodiment 2

[0052] Drop into and reclaim n-propanol 107g (93% of the low-boiling fraction propanol content of propyl propionate, 7% of propyl propionate content) in the reaction bottle of drying, replace air with nitrogen three times, then drop into aluminum sheet 1.33g, The specific surface area is 1.1cm 2 / g, and 0.3g of aluminum trichloride, at a heating rate of 2°C / min, the temperature was raised from 25°C to 97°C for reflux reaction for 3h, the temperature was lowered to 10°C, and the cooling rate was 2°C / min, and 600g of acrylic acid was added dropwise Aldehyde, and Tischenko, V. reaction at 10°C for 3h, atmospheric distillation at 80-99°C, reflux ratio 3:1 for 5h, recovery of n-propanol and crude propyl propionate, and crude Propyl propionate was rectified for 5 hours at 100-130°C with a reflux ratio of 5:1 to obtain 595.5g of propyl propionate product.

[0053] In this embodiment, based on the quality of propionaldehyde, it can be known through calculation that the yield of propy...

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Abstract

The invention provides a preparation method for preparing propyl propionate from recycled n-propanol, and relates to the technical field of production of ester chemical products. The preparation method provided by the invention comprises the following steps: under an anhydrous condition, recycled n-propanol, anhydrous aluminum trichloride and an aluminum sheet are mixed and subjected to a reflux reaction, a reflux reaction product is obtained, and the reflux reaction product comprises aluminum n-propoxide; the reflux reaction product is mixed with propionaldehyde to carry out a Tischenko, V. reaction so as to obtain a Tischenko, V. reaction product; and distilling and rectifying of the Tischenko, V. reaction product are carried out sequentially to obtain propyl propionate. According to thepreparation method provided by the invention, no water is generated in the production process, and the prepared propyl propionate is high in yield and purity. Results of embodiment show that: the yield of the propyl propionate prepared by the method is 95%-99%, and the purity of the propyl propionate is greater than 99%.

Description

technical field [0001] The invention relates to the technical field of production of ester chemical products, in particular to a method for preparing propyl propionate by recovering n-propanol. Background technique [0002] At present, the conventional production process in the propyl propionate industry is: using propionic acid and n-propanol as raw materials, the esterification reaction takes place under the conditions of sulfuric acid or strong acid ion exchange resin to obtain n-propyl propionate. But there is obvious shortcoming in this technological method, and its shortcoming mainly shows in the following aspects: produce water in the esterification process, its main raw material propionic acid and n-propanol are easily soluble in the water of generation, cause unreacted raw material and product propionic acid The separation of propyl ester is difficult, and the yield of propyl propionate is low. In addition, using n-propanol and propionic acid as raw materials requi...

Claims

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Application Information

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IPC IPC(8): C07C69/24C07C67/44C07C67/54
CPCC07C67/44C07C67/54C07C2527/126C07C69/24
Inventor 邓一建
Owner LEPING RUISHENG PHARMA CO LTD