Composition for diagnosing tuberculosis and method for diagnosing tuberculosis on basis of change in optical characteristics

A diagnostic method and composition technology, which can be used in scientific instruments, biological tests, material testing products, etc., can solve the problems of not yet developed technology for diagnosing tuberculosis by fluorescent nano-substance-antibody complexes, and achieve the effect of low detection limit
CN111465856APending Publication Date: 2020-07-28DXGEN CORP
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
DXGEN CORP
Publication Date
2020-07-28

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Abstract

The present invention relates to a composition for diagnosing tuberculosis and a method for diagnosing tuberculosis on the basis of a change in optical characteristics. The method for diagnosing tuberculosis is characterized in that the method is based on a change in optical characteristics of (a) a fluorescent nanomaterial-antibody complex and a fluorescent nanomaterial-antibody complex or (b) afluorescent nanomaterial-antibody complex and a metal nanoparticle-antibody complex. The method for diagnosing tuberculosis on the basis of a change in optical characteristics according to the presentinvention has a low detection limit and can rapidly and accurately measure tuberculosis since a change in fluorescence intensity of metal nanoparticles and fluorescent nanomaterials is utilized.
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Description

technical field

[0001] The present invention relates to a composition for diagnosing tuberculosis and a method for diagnosing tuberculosis based on changes in optical properties. Background technique

[0002] In general, tuberculosis is a disease with the highest incidence among notifiable infectious diseases in Korea, and is a disease caused by infection with Mycobacterium tuberculosis. Therefore, early diagnosis and treatment that can obtain reliable information from patients suspected of tuberculosis infection in a short period of time are more important than anything else.

[0003] The tuberculin skin test (TST) method is a routine method for diagnosing tuberculosis, but because of its low specificity, it has low reliability in diagnosing tuberculosis. However, it is still widely used due to its advantages of high sensitivity and low cost. The culture method is also widely used. As the most reliable detection method among various tuberculosis diagnostic methods, and as...

Claims

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