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Traditional Chinese medicine composition for treating eye disease of middle-aged and elderly people and preparation method

An ophthalmic disease and composition technology, applied in the field of traditional Chinese medicine compositions and preparations for treating middle-aged and elderly ophthalmic diseases, can solve the problems of high cost, complex drug composition, unsatisfactory curative effect, etc., and achieve low cost, treatment and improvement of diabetic retinopathy. and cataract, the effect of easy industrial production

Inactive Publication Date: 2020-09-11
广东珍盛懿生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There are many traditional Chinese medicine preparations disclosed for the treatment of ophthalmic diseases in middle-aged and elderly people, but most of them have complicated composition, high cost and unsatisfactory curative effect in the process of practical application

Method used

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  • Traditional Chinese medicine composition for treating eye disease of middle-aged and elderly people and preparation method
  • Traditional Chinese medicine composition for treating eye disease of middle-aged and elderly people and preparation method
  • Traditional Chinese medicine composition for treating eye disease of middle-aged and elderly people and preparation method

Examples

Experimental program
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Effect test

preparation example Construction

[0039] The preparation method of above-mentioned Chinese medicine composition, comprises the following steps:

[0040] (1) Separate the raw materials of the formula quantity, cook them with water steam for 2-3 hours, take them out and dry them in the sun to obtain the raw materials;

[0041] (2) Crushing the raw materials except rehmannia glutinosa in step (1) to pass through a 500-mesh sieve to obtain Chinese medicine powder;

[0042] (3) Decoct the raw material Rehmannia glutinosa obtained in step (1) with water for 2-3 times, filter, combine the filtrate, then add the Chinese medicine powder obtained in step (2), concentrate under reduced pressure to form an extract, which is the traditional Chinese medicine combination;

[0043] The amount of water added in the step (3) is: 5-10 times the weight of rehmannia glutinosa; the decocting condition is: decocting at 90-100° C. for 1-2 hours.

[0044] The present invention also provides the application of the above-mentioned tra...

Embodiment 1-5

[0052] The raw materials and consumption of Examples 1-5 are as shown in Table 1.

[0053] Table 1

[0054] Example 1 Example 2 Example 3 Example 4 Example 5 Rehmannia glutinosa \ parts by weight 0.6 1.5 0.8 1.2 1.0 Cistanche Herba \ parts by weight 0.8 1.2 0.9 1.1 1.0 Chrysanthemum \ parts by weight 0.4 1.0 0.7 0.8 0.6 Goji fruit \ parts by weight 0.5 1.2 0.7 1.0 0.8 Cornus meat \ parts by weight 0.1 0.5 0.3 0.4 0.2 Safflower \ parts by weight 0.2 0.6 0.3 0.5 0.4 Morinda officinalis\parts by weight 0.8 1.5 0.9 1.4 1.2 Buddisma \ parts by weight 0.1 0.4 0.15 0.3 0.2 Erigeron \ parts by weight 0.2 0.6 0.3 0.5 0.4

[0055] The preparation method of above-mentioned Chinese medicine composition, comprises the following steps:

[0056] (1) Separate the raw materials of the formula quantity, cook them with water steam for 3 hours, take them out and dry them in the sun to ...

experiment example 1 2

[0069] Experimental example 1. Effect of xylene on auricle swelling in mice

[0070] 120 Kunming mice, half male and half female, weighing 18-22 g, were randomly divided into 11 groups, 10 mice in each group. Blank control group: intragastric administration of equal volume of normal saline; experimental group: intragastric administration of the traditional Chinese medicine composition prepared in Examples 1-5 and Comparative Examples 1-4 respectively: safflower Chinese medicine powder (safflower traditional Chinese medicine powder) by intragastric administration of the safflower control group The preparation method is as follows: separate the safflower from water, boil it with water steam for 3 hours, take it out, dry it in the sun, crush it until it passes through a 500 mesh sieve, and obtain it), the dosage is 2g / kg, administered by intragastric administration once a day, and continuously 7 days. One hour after the last administration, 30 μL of xylene was applied to both si...

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Abstract

The invention discloses traditional Chinese medicine composition for treating eye disease of middle-aged and elderly people and a preparation method. The traditional Chinese medicine composition is prepared from the following raw materials: radix rehmanniae preparata, herba cistanche, flos chrysanthemi, fructus lycii, fructus corni, flos carthami, radix morindae officinalis, flos buddlejae and herba erigerontis. The preparation method comprises the following steps: (1) steaming the raw materials in the formula amount over water with steam for 2-3 h, and taking out and drying the raw materialsin the sun to obtain bulk drugs; (2) pulverizing the raw materials except radix rehmanniae preparata in step (1) to obtain traditional Chinese medicine powder; (3) adding water 2-3 times to the bulk drugs obtained in step (1), performing filtering, combining filtrates, adding the traditional Chinese medicine powder obtained in step (2), and performing concentration under reduced pressure to obtainextract. The composition has simple taste and moderate price, is safe and reliable, and can effectively treat and improve ophthalmic diseases such as diabetic retinopathy and cataract.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition and a preparation method for treating middle-aged and elderly eye diseases. Background technique [0002] With the increase of age and the aging of body sensory organs, many diseases will occur. In addition to common senile diseases such as hypertension, diabetes, and coronary heart disease, senile eye diseases such as cataract, glaucoma, and diabetic retinopathy are also increasingly frequent, seriously affecting Vision and quality of life in older adults. [0003] CN102416106A discloses a traditional Chinese medicine for treating middle-aged and elderly eye diseases, which is composed of antelope horn, terrestris, horsetail, chrysanthemum, plantain seed, prunella vulgaris, cassia seed, ginseng, dogwood, dendrobium, medlar fruit, dodder fruit, privet fruit, stone Cassia, Coptidis, Gujingcao, Akebia, Re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P27/02A61P9/10A61P27/12A61P3/10
CPCA61K36/28A61K36/286A61K36/287A61K36/40A61K36/56A61K36/64A61K36/746A61K36/804A61K36/815A61K2236/331A61K2236/39A61P3/10A61P9/10A61P27/02A61P27/12A61K2300/00
Inventor 詹容珍
Owner 广东珍盛懿生物医药有限公司
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