All-component extraction method of lucid ganoderma

An extraction method and a full-component technology, which are applied in the field of full-component extraction of Ganoderma lucidum, can solve the problems of waste of useful components extraction, low utilization rate of Ganoderma lucidum, etc., and achieve the effect of a simple method.

Pending Publication Date: 2020-09-15
广东悦生生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] In the prior art, research on the extraction of Ganoderma lucidum mostly focuses on Ganoderma lucidum spores, polysaccharides, polypeptides and triterpenes of Ganoderma lucidum, but Ganoderma lucidum contains many active ingredients, and the proportion of polysaccharides and other components of Ganoderma lucidum is only a small part, resulting in many The useful ingredients are wasted during the extraction process, and the utilization rate of Ganoderma lucidum is not high; therefore, it is necessary to study a method for extracting all components of Ganoderma lucidum to extract most of the useful ingredients in Ganoderma lucidum

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A method for extracting all components of Ganoderma lucidum, comprising the following steps:

[0029] S1. Low-temperature ultra-micromolecular grinding. Under low temperature conditions, the perennial non-dusted dry Ganoderma lucidum is ultra-finely pulverized, and then passed through molecular sieves, so that the particle size of the Ganoderma lucidum particles is not greater than 40nm;

[0030] S2. Supercritical carbon dioxide extraction of Ganoderma lucidum essence powder, using supercritical fluid extraction to obtain Ganoderma lucidum essence powder and residue A. During extraction, the pressure was 40MPa, the temperature was 10°C, and the extraction time was 4h;

[0031] S3. Alcohol extraction of triterpenoids, lowering the pressure and raising the temperature, using the reflux method for alcohol extraction of residue A to obtain triterpenoids and residue B, the pressure is 25MPa, the temperature is 20°C, and the extraction time is 3h;

[0032] S4. Extract Ganoder...

Embodiment 2

[0039] A method for extracting all components of Ganoderma lucidum, comprising the following steps:

[0040] S1. Low-temperature ultra-micromolecular grinding. Under low temperature conditions, the perennial non-dusted dry Ganoderma lucidum is ultra-finely pulverized, and then passed through molecular sieves, so that the particle size of the Ganoderma lucidum particles is not greater than 40nm;

[0041] S2. Supercritical carbon dioxide extraction of Ganoderma lucidum essence powder, using supercritical fluid extraction to obtain Ganoderma lucidum essence powder and residue A. During extraction, the pressure was 45MPa, the temperature was 8°C, and the extraction time was 3h;

[0042] S3. Alcohol extraction of triterpenoids, lowering the pressure and raising the temperature, using the reflux method for alcohol extraction of residue A to obtain triterpenoids and residue B, the pressure is 30MPa, the temperature is 18°C, and the extraction time is 2.5h;

[0043] S4. Extract Ganode...

Embodiment 3

[0050] A method for extracting all components of Ganoderma lucidum, comprising the following steps:

[0051] S1. Low-temperature ultra-micromolecular grinding. Under low temperature conditions, the perennial non-dusted dry Ganoderma lucidum is ultra-finely pulverized, and then passed through molecular sieves, so that the particle size of the Ganoderma lucidum particles is not greater than 40nm;

[0052] S2. Supercritical carbon dioxide extraction of Ganoderma lucidum essence powder, using supercritical fluid extraction to obtain Ganoderma lucidum essence powder and residue A. During extraction, the pressure was 50MPa, the temperature was 5°C, and the extraction time was 2h;

[0053] S3. Alcohol extraction of triterpenoids, lowering the pressure and raising the temperature, using the reflux method for alcohol extraction of residue A to obtain triterpenoids and residue B, the pressure is 35MPa, the temperature is 15°C, and the extraction time is 2h;

[0054] S4. Extract Ganoderm...

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Abstract

The invention discloses an all-component extraction method of lucid ganoderma. The method comprises the following steps: carrying out low-temperature ultramicro molecular grinding, carrying out supercritical carbon dioxide extraction on lucid ganoderma essence powder, extracting triterpenoids with alcohol, extracting ganoderan, extracting protein, extracting other active substances, extracting nutrient substances such as amino acids and the like, and extracting residual nutrient components. Most nutritional ingredients and active ingredients in the lucid ganoderma can be obtained through classified extraction, different ingredients are used for different purposes, the overall utilization rate of the lucid ganoderma is far higher than that of a common extraction method, the total yield of the extract can reach 65% or above of the dry weight of the lucid ganoderma, and the purity of the extract is higher; in the preparation process, components such as ganoderma triterpenes, ganoderan, proteins, adenosine, mannitol, ergosterol, vitamins and amino acids are obtained through low-temperature wall breaking, fractional extraction and respective purification, and the preparation method hasthe characteristics of being simple, high in extraction rate and high in total product specific gravity.

Description

technical field [0001] The invention relates to the technical field of Ganoderma lucidum extraction, in particular to a method for extracting all components of Ganoderma lucidum. Background technique [0002] The scientific name of Ganoderma lucidum is Ganoderma Lucidum Karst. It is the fruiting body of Ganoderma lucidum, a fungus of Polyporaceae. The fruiting body of Ganoderma lucidum is an umbrella-shaped mushroom, which is purple-red or brown-red. Its texture is fleshy when it is young, and it becomes corky when it matures and dries. The fruiting body consists of a cap (cap) and a stipe. From "Shen Nong's Materia Medica" to "Pharmacopoeia of the People's Republic of China", the Ganoderma lucidum refers to the fruiting body of Ganoderma lucidum. The chemical composition of Ganoderma lucidum is relatively complex, and the active ingredients can be divided into ten categories, including Ganoderma lucidum polysaccharides, Ganoderma lucidum polypeptides, triterpenoids, 16 ki...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B37/00C07K1/30C07K1/14C07C31/26C07C29/76C07C29/86C07H1/08C07H19/167A23L33/10A23L31/00C07J9/00
CPCA23V2002/00A23L31/00A23L33/10C07C29/76C07C29/86C07H1/08C07H19/167C07J9/00C07K1/145C07K1/30C08B37/0003C07C31/26A23V2200/30A23V2250/208A23V2300/14Y02P20/54
Inventor 付鹏史东鑫
Owner 广东悦生生物科技有限公司
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