Method for realizing synchronous monitoring of microcirculation and pulse by adopting mobile phone camera
A mobile phone camera and pulse technology, applied in the field of biomedical imaging, can solve the problems of high price, complicated operation, poor portability, etc., and achieve the effects of high accuracy, high portability, and easy operation
Active Publication Date: 2020-09-22
UNIV OF SHANGHAI FOR SCI & TECH
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Problems solved by technology
Current darkfield imaging technique, which is a derivative technique of orthogonal polarization spectroscopy, has higher resolution for white blood cells and red blood cells in the microcirculation, but the data analysis part is still time-consuming
Laser Doppler technology, after scattering the laser light emitted by the tissue, the wavelength of the laser light hitting the blood cells undergoes a Doppler frequency shift to monitor blood flow changes, but this method is a single-point measurement and can only measure blood vessels with a diameter of 1mm
[0005] If multiple machines are used to separately collect heart rate information and microcirculation information, and analyze and integrate the obtained information, this will lead to complicated operation, high price, and poor portability. There may be errors in the physiological information
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[0033] Such as figure 2 As shown, the device adopted in this embodiment includes a first laser 1 for emitting a first laser, a first beam expander 2 for passing the first laser, a second laser for emitting a second laser, and a second laser for emitting a second laser. The second beam expander through which the second laser passes, the mobile phone camera 5 for taking pictures, and the computer 6 for analyzing and processing the images.
[0034] Such as figure 1 As shown, a method of using a mobile phone camera to realize synchronous monitoring of microcirculation and pulse in this embodiment includes the following steps:
[0035] Step 1: Use the first laser to emit the first laser of 632nm and 15mW, and the second laser to emit the second laser of 530nm and 15mW to pass through the first beam expander and the second beam expander respectively, and hit the fingertip at the same time. Place it still on a flat surface, and then use a mobile phone camera to take pictures of th...
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The invention provides a method for realizing synchronous monitoring of microcirculation and pulse by adopting a mobile phone camera. The method comprises the following steps: emitting two beams of laser with different wavelengths to a to-be-detected part through a beam expander; analyzing a speckle image generated by irradiating laser with shorter wavelength on the skin surface tissue to obtain apulse wave signal generated by cardiac impulse; collecting a speckle image generated by red blood cell displacement by using laser with longer wavelength, and further analyzing to obtain a blood perfusion amount and a rhythm period; collecting a plurality of frames of speckle images in continuous time by adopting a mobile phone camera; processing red and green channels of each frame of image, andperforming up-sampling interpolation based on the spatial distribution characteristics of the speckle signals to enhance the speckle signals; finally, carrying out speckle contrast analysis on the image of the red channel, carrying out gray level co-occurrence matrix analysis on the image of the green channel, so that the microcirculation blood perfusion amount, the rhythm period and the pulse change rule are obtained.
Description
technical field [0001] The invention belongs to the field of biomedical imaging, and in particular relates to a method for realizing synchronous monitoring of microcirculation and pulse by using a mobile phone camera. Background technique [0002] Monitoring the heartbeat and microcirculation system is of great significance to the study of the physiological state of the human body. The human body is a complex organism, and all tissue cells are closely connected. The monitoring of the physiological state of the human body should be linked and monitored synchronously. [0003] Existing methods for monitoring heart rate mainly include: blood oxygen method, which obtains blood oxygen information and heart rate through the different absorption rates of oxyhemoglobin and reduced hemoglobin to different light sources, but it needs to penetrate tissues, so it can only be detected on the fingertips of the human body. Use on thin skin tissue such as tips and ear lobes. Ultrasonic me...
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IPC IPC(8): G16H80/00G06T7/00
CPCG16H80/00G06T7/0012G06T2207/30101
Inventor 杨晖徐昊林昭苏于诤刘省龙李然刘铁龙
Owner UNIV OF SHANGHAI FOR SCI & TECH