Periplaneta americana preparation, and preparation method and application thereof
The technology of Periplaneta americana and preparations is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. It can solve the problems of large side effects and poor prognosis, and achieves the promotion of dissolution and improvement of extraction efficiency. , the effect of improving utilization
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[0042] On the basis of the above-mentioned technical scheme, the embodiment of the present invention provides a kind of preparation method of above-mentioned Periplaneta americana preparation, comprises the steps:
[0043] S01, providing Periplaneta americana and vinegar, the acidity of the vinegar is above 6.0g / 100mL;
[0044] S02, mixing the Periplaneta americana with the vinegar, and fermenting.
[0045] According to the preparation method of the American cockroach preparation provided by the present invention, vinegar with an acidity of more than 6.0g / 100mL and the American cockroach are mixed and fermented, which greatly improves the utilization rate and extraction efficiency of the American cockroach. On the one hand, the vinegar can be used as a fermentation system, without adding other microbial strains to participate in the fermentation, and the acidity is high, no need to strictly control the sterile environment, easy to operate, and can be produced on a large scale;...
Embodiment 1
[0070] The present embodiment provides a kind of preparation method of Periplaneta americana preparation, comprises the steps:
[0071] 1. Take the adults of Periplaneta americana 10-15 days after stopping feeding, spray and wash them with clean water, and drain the water; spray the cleaned Periplaneta americana with balsamic vinegar to reduce the activity of Periplaneta americana; The inactivated Periplaneta americana is put into the fermenter, compacted slightly, leaving no gaps.
[0072] 2. Take jiuqu balsam vinegar (acidity ≥ 6.0g / 100mL), and then add the jiu balsamic vinegar into the fermenter slightly compacted with Periplaneta americana, at least make the jiu balsamic vinegar not pass through the fermenter The American cockroach in; Wherein, the mixing mass ratio of the American cockroach in the fermenter and Jiuqu balsamic ester vinegar is 1:1.
[0073] 3. Carry out sealed fermentation in the fermenter for 1 month, take out the fermentation product, and use an ultra-h...
Embodiment 2
[0076] This example provides a Periplaneta americana preparation, the difference from Example 1 is: after the homogenate in step 3, add pangolin scales that have been pulverized and passed through a 100-mesh sieve, mix well, and add An appropriate amount of honey and other auxiliary materials are prepared into pills; wherein, based on 20 parts by weight of the homogenized product of Example 1, 30 parts by weight of pangolin scales.
[0077] The rest are basically the same as those in Embodiment 1, and will not be repeated here.
[0078] After testing, in the Periplaneta americana preparation of this embodiment, the active peptide content is 5.79g / 100g, the total amino acid content is 2.904g / 100g, and the total flavonoid content is 155.04mg / 100g.
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Abstract
Description
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