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Application of ophioglossum and semen plantaginis composition to preparation of pharmaceutical composition for lowering blood sugar and blood pressure

A composition and technology of psyllium seed, applied in the direction of drug combination, application, and medical raw materials derived from ferns/filamentous plants, etc., can solve problems such as side effects, physical discomfort, and non-appearance, and achieve obvious curative effects

Inactive Publication Date: 2020-10-16
XIAMEN MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, some types of high blood pressure drugs can cause side effects, causing patients to feel uncomfortable after taking them. Therefore, the current high blood pressure drugs are only adopted after large-scale research and evaluation of efficacy and side effects
[0006] Pinger Xiaocao and Psyllium Semen are used to treat diabetes and high blood pressure in a traditional Chinese medicine composition that has not yet appeared on the market

Method used

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  • Application of ophioglossum and semen plantaginis composition to preparation of pharmaceutical composition for lowering blood sugar and blood pressure
  • Application of ophioglossum and semen plantaginis composition to preparation of pharmaceutical composition for lowering blood sugar and blood pressure
  • Application of ophioglossum and semen plantaginis composition to preparation of pharmaceutical composition for lowering blood sugar and blood pressure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The oral pharmaceutical composition in this example is composed of the original powder of Plantago chinensis and the extract of Pinger Xiaocao, wherein the preparation of Pinger Xiaocao extract is: washing Pinger Xiaocao, drying and chopping And grind it into powder, add ethanol water mixed solvent (volume ratio of ethanol to water 7:3), soak for 1 day, after solid-liquid separation, put the obtained liquid at room temperature and air-dry, and it is ready.

[0037] (1) Experimental process:

[0038] 1. Acute hypoglycemic ability:

[0039] At 23:00 in the evening, the high-oil diet induced diabetic ICR mice (starvation blood glucose > 130 mg / dL) were deprived of water and food for 10 hours. At 9:00 the next morning, measure the initial blood glucose level, feed each tube with 0.2mL of the above oral pharmaceutical composition, and then give 4g / kg glucose, and start timing, use Accu-chek (Model Instant) blood glucose every 30 minutes The machine measured blood glucose o...

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Abstract

The invention discloses an application of ophioglossum and semen plantaginis composition to preparation of pharmaceutical composition for lowering blood sugar and blood pressure. The pharmaceutical composition is administered orally, and the ophioglossum and semen plantaginis composition is composed of semen plantaginis technical powder or extract and ophioglossum technical powder or extract. Theophioglossum and semen plantaginis composition has obvious curative effects on lowering blood sugar and blood pressure, and can be used for preparing effective pharmaceutical composition for treatingindividuals with diabetes (and) or hypertension.

Description

technical field [0001] The invention belongs to the technical field of Chinese patent medicines, and in particular relates to the application of Pinger Xiaocao and Psyllium Semen composition in the preparation of a drug composition for lowering blood sugar and blood pressure. Background technique [0002] The current treatment of diabetes is divided into three parts: regular exercise, diet control and drug treatment. The drug treatment of diabetes is divided into oral hypoglycemic drugs or insulin injections; when blood sugar is still poorly controlled after oral hypoglycemic drugs, it may be necessary to switch to insulin injections. However, with the different mechanism of action of the drug, the time of taking the drug is also different: first, the drug taken 30 minutes before the meal, immediately before the meal or taken with the meal, most of these drugs have the function of stimulating insulin secretion; , a medicine taken after meals, which is used to improve insuli...

Claims

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Application Information

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IPC IPC(8): A61K36/68A61P3/10A61P9/12A23L33/105A23L33/00
CPCA23V2002/00A61K36/12A61K36/68A61K2236/331A61K2236/333A23L33/00A23L33/105A61P3/10A61P9/12A61K2300/00A23V2200/328A23V2250/21
Inventor 傅耀贤翁庆丰陈思霈陈永轩伊雪
Owner XIAMEN MEDICAL COLLEGE
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