Liquid path system for chemiluminescence analyzer

Abstract

The invention discloses a liquid path system for a chemiluminiscence analyzer. The liquid path system comprises a sample adding system, a cleaning liquid injection system, a magnetic bead cleaning system, a liquid pumping system, a substrate liquid injection system and a discharging system. The automatic detection requirement of high-flux samples can be effectively met, the magnetic bead cleaningsystem and the sample adding system both have a self-cleaning function, each pump body of the multi-channel plunger pump of the magnetic bead cleaning system corresponds to one liquid injection branchpipe and one liquid injection needle, independent control over each liquid injection needle is achieved, the inconsistent liquid injection amount caused by different pipe resistances is effectively prevented, so that the liquid injection precision and the uniformity of the liquid injection amount are improved; meanwhile, the state of the tenth electromagnetic valve can be selectively switched inthe BF washing liquid injection and cleaning process, then self-cleaning of the magnetic bead cleaning system is achieved, crystallization caused by residual crystallization washing liquid in a pipeline is avoided, the liquid injection precision and the uniformity of the liquid injection amount are further improved, and the BF washing liquid can be prevented from being injected into the reaction disc to form crystal substances.

Description

technical field [0001] The invention relates to a liquid circuit system, in particular to a liquid circuit system for a chemiluminescence analyzer. Background technique [0002] Chemiluminescence analysis has been recognized more and more for its characteristics of extremely high sensitivity, good selectivity, fast analysis speed, and wide linear range. Chemiluminescence analysis is one of the mainstream research directions in clinical testing at present. The application range of chemiluminescence assay analyzers based on chemiluminescence analysis is becoming wider and wider. The stability, consistency, accuracy and other performance indicators of the instrument system more and more important. [0003] Chemiluminescence labeling analyzer, also known as chemiluminescence analyzer (CLIA), is a medical testing instrument that analyzes the human body by detecting patient serum. At the time of detection, quantitative patient serum and horseradish peroxidase (HRP) are added to ...

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Problems solved by technology

[0005] According to statistics, at present, most of the detection failures of chemiluminescence analyzers are due to the failure of the liquid circuit. For example, the existing magnetic bead cleaning module cannot clean the pipeline, and because the BF washing liquid is easy to crystallize, the pipeline is blocked, which affects the BF washing. Quantitative liquid injection accuracy of the liquid, and instrument failure will occur after long-term operation; at the same time, the flow resistance of each branch of the magnetic bead cleaning pipeline is a non-fixed value, resulting in poor consistency of liquid injection and affecting the accuracy of liquid injection;

[0006] The waste liquid discharge system of the existing sampling needle uses a diaphragm pump to directly discharge the waste liquid in the cleaning pool. However, with the rapid development of high-throughput instruments, the time for pumping waste liquid is greatly shortened, and the pipeline resistance As a result, the power of the diaphragm pump attenuates with the prolongation of the use time, resulting in the waste liquid in the cleaning tank not being pumped away in time or remaining, which further leads to the phenomenon of wall hanging on the outer wall of the sampling needle, and the risk of sample cross-contamination. Affect the reliability of the test results, and the liquid is easy to drop on the surface of the instrument, which affects the cleanliness and further affects the competitiveness of the enterprise

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