Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Breast cancer patient disease-free lifetime prediction model and construction method thereof

A prediction model and survival technology, applied in mammography, medical simulation, biological systems, etc., can solve problems such as poor prognosis, no unified diagnosis and treatment prediction standard for molecular classification of breast cancer, lack of prospective research support, etc., and achieve enhanced treatment Effects of intervention, reduction of recurrence risk, and optimization of treatment options

Active Publication Date: 2021-01-05
SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
View PDF3 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of these methods are limited to the prediction of specific populations, and lack the support of prospective studies with high levels of evidence
In addition, there is no unified diagnosis and treatment prediction standard for some important molecular types of breast cancer, such as other types of triple-negative breast cancer with poor prognosis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Breast cancer patient disease-free lifetime prediction model and construction method thereof
  • Breast cancer patient disease-free lifetime prediction model and construction method thereof
  • Breast cancer patient disease-free lifetime prediction model and construction method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0037] In order to better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0038] The construction process of a disease-free survival prediction model for patients with breast cancer of the present invention is as follows (technical route is as follows: figure 1 shown):

[0039] 1. Patient Screening

[0040] Inclusion criteria: (1) female patients, over 18 years old; (2) patients with early breast cancer (TNM stage I-III, according to the 8th edition of AJCC staging); (3) patients who have been diagnosed with unilateral breast cancer by histopathology. Breast cancer without distant organ metastasis; (4) The patient has undergone surgery or axillary lymph node dissection, and pathological biopsy has been performed to confirm the status of the axillary lymph nodes; Scan-enhanced sequence (T1+C), T2-weighted sequence...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a breast cancer patient disease-free lifetime prediction model and a construction method thereof. The method builds a breast cancer patient disease-free lifetime artificial intelligence prediction model by employing an artificial intelligence machine learning algorithm based on the magnetic resonance image data and clinical feature data of a breast cancer patient, and can make early breast cancer patients effectively divided into a high-risk group and a low-risk group. The prediction model has the advantages of accuracy, simplicity, convenience, noninvasiveness and thelike, can effectively evaluate the postoperative disease-free lifetime of early breast cancer patients, is helpful for assisting clinicians to optimize treatment schemes, strengthens treatment intervention on high-risk patients as soon as possible, reduces recurrence risks of the patients, and has important guiding significance for guiding clinical treatment strategies and enhancing clinical treatment intervention and subsequent individualized follow-up visits.

Description

technical field [0001] The invention belongs to the field of biomedicine, and relates to a prediction model of disease-free survival period of breast cancer patients and a construction method thereof. Background technique [0002] Breast cancer is a malignant tumor that seriously endangers women's health. It accounts for the first incidence rate of female malignant tumors and the fifth death rate. The incidence rate is also increasing year by year. About 30%-40% of breast cancer patients undergo recurrence and metastasis after surgery and postoperative adjuvant therapy, and eventually develop into advanced breast cancer, and the 5-year survival rate is less than 23%. Research on the risk of recurrence and metastasis of early breast cancer has shown that, in addition to age and tumor size, preoperative axillary lymph node (ALN) status, pathological complete response (pCR) after neoadjuvant chemotherapy, molecular typing and related gene expression, etc. It is also an importa...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G16H50/70G16H50/50G16H30/40G16B40/00G16B5/00A61B5/055A61B5/00
CPCG16H50/50G16H50/70G16H30/40G16B40/00G16B5/00A61B5/055A61B5/004A61B5/4312
Inventor 姚和瑞宋尔卫余运芳谭钰洁陈勇健何子凡
Owner SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products